Results 171 to 180 of about 3,620,454 (291)

t-gibbons/NEMO-Analysis: Updated Code: May 2024

<p>Code base updated and used for analysis as of May 2024.</p ...
t-gibbons
core   +1 more source

Three phosphatase families form a community: The phosphohydrolases that act upon inositol pyrophosphates

FEBS Letters, EarlyView.
Inositol pyrophosphates are energy‐rich signaling molecules that perform critical functions in cells. Three different families of phosphatases hydrolyze the β phosphate of the inositol pyrophosphate molecules: two have narrow specificities and one is promiscuous.
Ronda J. Rolfes
wiley   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Using Pattern Languages in Participatory Design

In this paper, we examine the contribution that pattern languages could make to user participation in the design of interactive systems, and we report on our experiences of using pattern languages in this way. In recent years, there has been a growing
Dearden, A, McManus, B, Finlay, J, Allgar, E   +3 more
core  

Recent developments in multivariate pattern analysis for functional MRI

, 2012
Multivariate pattern analysis (MVPA) is a recently-developed approach for functional magnetic resonance imaging (fMRI) data analyses. Compared with the traditional univariate methods, MVPA is more sensitive to subtle changes in multivariate patterns in ...
Fang, Fang, Weng, Xuchu, Yang, Z (reprint author), Chinese Acad Sci, Inst Psychol, Key Lab Behav Sci, Beijing 100101, Peoples R China., Yang, Zhi   +3 more
core  

C082 | T-CELL RECEPTOR-VΒ REPERTOIRE FLOW CYTOMETRY ANALYSIS SHOWED ABSOLUTE CONCORDANCE WITH MOLECULAR ANALYSIS OF TCR GENE REARRANGEMENT IN THE DIAGNOSIS OF T-CELL LYMPHOPROLIFERATIVE DISORDER: OBSERVATIONAL STUDY FROM A SINGLE CENTER EXPERIENCE.

Haematologica
Background: Clonality assessment is critical to differentiate between reactive and pathological T- cell lymphocytosis, and it usually relies on molecular analysis of T-Cell Receptor (TCR) gene rearrangement, which is considered the gold standard assay ...
M. Antonacci, J. Micozzi, A. Costa, A. Laganà, M.L. Milani, S. Intoppa, V. Bellomarino, M.G. Nardacci, M. Biglietto, S. Imperatore, M.L. Bisegna, M. Martelli, I. Della Starza, M.S. De Propris   +13 more
doaj  

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

FEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens, Brendan W. Chandler, Anna M. Schmoker, Jaye L. Weinert, Charlotte A. Kearns, Warren T. Yacawych, Amila Šemić, Alicia M. Ebert, Bryan A. Ballif   +8 more
wiley   +1 more source

Transcriptomic Analysis Reveals Molecular Mechanisms of Fleeing, Adhesion, and Thanatosis Patterns in Sea Cucumber <i>Apostichopus japonicus</i>. [PDF]

Biology (Basel)
Wu G, Wu H, Wang X, Gao Q, Zhao C.
europepmc   +1 more source

Mixed‐class J‐domain protein scaffolds promote expanded aggregate handling and multivalent Hsp70 engagement during functional disaggregase assembly

FEBS Letters, EarlyView.
Protein aggregates threaten proteostasis and cell health. In human cells, Hsp70–J‐domain protein‐based disaggregases remove aggregates, but how they assemble remains unclear. Our biochemical findings show that DNAJA2‐ and DNAJB1‐containing disaggregase scaffolds enhance luciferase aggregate targeting, and that Hsp70 recruitment by both J‐domain ...
Anna Szlachcic, Nadinath B. Nillegoda
wiley   +1 more source

Acceptability and impact on health-related markers of a sustainable dietary pattern: results from a pilot randomized controlled cross-over study. [PDF]

Eur J Nutr
Vinelli V, Tucci M, Martini D, Rendine M, Venturi S, Perna S, Gargari G, Mantegazza G, Gardana C, Battezzati A, Leone A, Sucato S, Fustinoni S, Guglielmetti S, Porrini M, Del Bo' C, Riso P.   +16 more
europepmc   +1 more source