Results 151 to 160 of about 33,656,568 (290)
Misses' coat-frock with sleeveless underblouse, 1919
, 1919 Pattern No. 4758: Underblouse with a shallow "modesty" trimmed with "narrow ruffles of organdie." Neckline and hem of blouse are trimmed with contrasting material. Narrow-collared waistcoat is finished along the back seams with buttons.
Vogue Pattern Service
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Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
Frock with set-in side sections, 1920
, 1920 Pattern No. 4691: Shirtwaist with bias-cut sleeves, frilling at the neckline, and set-in sections that are "cut sufficiently long to turn up, forming pockets with the skirt at either side." Belt is tied at the center back, and shirtwaist and skirt are ...
Vogue Pattern Service
core
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source
The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
wiley +1 more source
Coat with set-in waistcoat and simple skirt, 1919
, 1919 Pattern No. 4670-71: Double-collared coat trimmed in braid with shirred vest, set-in pockets, and bell sleeves gathered at the wrist. Hobble skirt trimmed with braid.
Vogue Pattern Service
core
FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
wiley +1 more source
Belted skirt with tunic and shirtwaist; and, frock with wrapped tunic, 1919
, 1919 Pattern No. 4538-39: Shirtwaist with decorative front panel and sleeves "slightly flared at the wrist." Hobble skirt with decorative belt and tunic that flows from the hips. Accessorized with a beret-like hat with a pompom. Pattern No.
Vogue Pattern Service
core
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source