Differential Binding of cAMP‐responsive‐element(CRE)‐binding Protein‐1 and Activating Transcription Factor‐2 to a CRE‐Like Element in the Human Tissue‐Type Plasminogen Activator (t‐PA) Gene Promoter Correlates with Opposite Regulation of t‐PA by Phorbol Ester in HT‐1080 and HeLa Cells [PDF]
, 1996 Magdaline Costa, Robert L. Medcalf
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Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss
iMetaMed, EarlyView.As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu +6 more
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Plasminogen activators play an essential role in extracellular-matrix invasion by lymphoblastic T cells [PDF]
, 1997 Lars S. Reiter +2 more
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A personal 360° view of applications of ‘biomimetic’ molecular recognition
Journal of Chemical Technology &Biotechnology, EarlyView.Abstract Molecular recognition between biological molecules has formed the basis for innumerable applications in biotechnology for the last seven decades or so. Techniques such as affinity chromatography, solid‐phase and aqueous two‐phase extraction, affinity precipitation, biomimetic catalytic systems, biosensors and molecular imprinting all exploit ...
Christopher R Lowe
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Lasers in Surgery and Medicine, EarlyView.ABSTRACT Background Postinflammatory hyperpigmentation (PIH) is the most common adverse effect following laser treatments, yet the relative efficacy of proposed prophylactic measures remains uncertain. Objectives To compare the effectiveness of available interventions for preventing laser‐induced PIH in randomized controlled trials (RCTs).
Supisara Wongdama +5 more
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Emergency nurses\' knowledge and adherence to tissue plasminogen activator guidelines for patients with stroke [PDF]
حیاتBackground & Aim: Stroke, as the primary and most critical cerebrovascular condition, is known as a leading cause of disability and mortality. Timely and appropriate care plays an important role in reducing death and associated complications. The purpose
Elnaz Asghari +4 more
doaj
Med Research, EarlyView.ABSTRACT Circadian rhythms orchestrate cardiovascular physiology by regulating immune and inflammatory pathways. Disruption of these rhythms profoundly alters vascular homeostasis, thereby promoting the onset and progression of cardiovascular diseases (CVD).
Tian Zhang +22 more
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Urokinase-type plasminogen activator inhibits α4β1 integrin-mediated T lymphocyte adhesion to fibronectin independently of its catalytic activity [PDF]
, 1999 Philippe Olivier +3 more
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Human Cyclophilins—An Emerging Class of Drug Targets
Medicinal Research Reviews, EarlyView.ABSTRACT Cyclophilins are a family of enzymes with peptidyl‐prolyl isomerase activity found in all cells of all organisms. To date, 17 cyclophilin isoforms have been identified in the human body, participating in diverse biological processes. Consequently, cyclophilins have emerged as promising targets for drug development to address a wide array of ...
Katarina Jurkova +3 more
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Tumor Cell Migration May Be an Inherent “Foraging” Behavior
Medicine Advances, EarlyView.Tumor cells gradually form pseudopodia, migrate to necrotic cells, make contact with them, and absorb necrotic cell debris. During this migration, small vesicles formed by dying tumor cells also gradually migrate toward living tumor cells. Once the nutrients from the necrotic cells have been completely absorbed, the living tumor cells will leave ...
Fuqian Zhao +4 more
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