Results 171 to 180 of about 681,261 (380)

Degradation of connective tissue matrices by macrophages. III. Morphological and biochemical studies on extracellular, pericellular, and intracellular events in matrix proteolysis by macrophages in culture. [PDF]

, 1980
We have shown that macrophages in culture degrade the glycoproteins and amorphous elastin of insoluble extracellular matrices. Ultrastructural observation of the macrophage-matrix interaction revealed that connective tissue macromolecules were ...
Bainton, DF, Jones, PA, Werb, Z
core  

Complication associated with intravitreal injection of tissue plasminogen activator for treatment of submacular hemorrhage due to rupture of retinal arterial macroaneurysm

American Journal of Ophthalmology Case Reports, 2019
Purpose: To report the possible complications of intravitreal injection of tissue plasminogen activator (t-PA) for the treatment of submacular hemorrhage associated with retinal arterial macroaneurysm (RAM).
Eiko Tsuiki, Mao Kusano, Takashi Kitaoka
doaj  

Interactions of plasminogen and tissue plasminogen activator (t-PA) with amphoterin. Enhancement of t-PA-catalyzed plasminogen activation by amphoterin.

, 1991
J Parkkinen, Heikki Rauvala
openalex   +1 more source

Differential Binding of cAMP‐responsive‐element(CRE)‐binding Protein‐1 and Activating Transcription Factor‐2 to a CRE‐Like Element in the Human Tissue‐Type Plasminogen Activator (t‐PA) Gene Promoter Correlates with Opposite Regulation of t‐PA by Phorbol Ester in HT‐1080 and HeLa Cells [PDF]

, 1996
Magdaline Costa, Robert L. Medcalf
openalex   +1 more source

Identification of Senomorphic miRNAs in Embryonic Progenitor and Adult Stem Cell‐Derived Extracellular Vesicles

Aging Cell, EarlyView.
A senomorphic miRNA cocktail (E5), consisting of miR‐181a‐5p, miR‐92a‐3p, miR‐21‐5p, and miR‐186‐5p, was identified from a pool of miRNAs enriched in extracellular vesicles (EVs) derived from multiple functional human stem cell types. E5 reduces senescence and SASP markers both in cell culture and in aged mice.
Tianpeng Zhang, Allancer D. C. Nunes, Jieun Lee, Dana Larocca, Giovanni Camussi, Sai Kiang Lim, Vicky U. Bascones, Luise Angelini, Ryan D. O'Kelly, Xiao Dong, Laura J. Niedernhofer, Paul D. Robbins   +11 more
wiley   +1 more source

Polyoma Middle T-induced Vascular Tumor Formation: The Role of the Plasminogen Activator/Plasmin System

, 1997
Kanaga Sabapathy, Michael S. Pepper, Friedemann Kiefer, Uta Möhle-Steinlein, Fabienne Tacchini‐Cottier, Ingrid Fetka, Georg Breier, Werner Risau, Peter Carmeliet, Roberto Montesano, Erwin F. Wagner   +10 more
openalex   +1 more source

Importance of GlcUAβ1-3GalNAc(4S,6S) in chondroitin sulfate E for t-PA- and u-PA-mediated Glu-plasminogen activation [PDF]

, 2000
Tokiko Sakai, Mamoru Kyogashima, Yutaka Kariya, Tetsumei Urano, Yumiko Takada, Akikazu Takada   +5 more
openalex   +1 more source

Tissue plasminogen activator-based nanothrombolysis for ischemic stroke

Expert Opinion on Drug Delivery, 2018
Shang-ji Liu, Xiaozhou Feng, R. Jin, Guohong Li   +3 more
semanticscholar   +1 more source

Reducing HuD Levels Alleviates Alzheimer's Disease Pathology in 5xFAD Mice

Aging Cell, EarlyView.
The effect of ablating expression of the RNA‐binding protein HuD (ELAVL4) in neurons was evaluated in the Alzheimer's mouse model 5xFAD. We found that conditional removal of HuD resulted in diminished Aβ plaque formation and reduced AD‐associated hyperactivity in 5xFAD/HuDcKO mice relative to 5xFAD mice.
Eunbyul Ji, Apala Pal, Quia C. Claybourne, Marc Michel, Rachel Munk, Ross A. McDevitt, Chang‐Yi Cui, Myriam Gorospe   +7 more
wiley   +1 more source

Quercetin Reduces Vascular Senescence and Inflammation in Symptomatic Male but Not Female Coronary Artery Disease Patients

Aging Cell, EarlyView.
In male patients undergoing CABG surgery, pretreatment with quercetin suppressed inflammaging and its associated inflammation, leading to improved endothelium‐dependent relaxation (measured ex vivo) and reducing new onset of post‐operative atrial fibrillation.
Pauline Mury, Olina Dagher, Annik Fortier, Ariel Diaz, Yoan Lamarche, Pierre‐Emmanuel Noly, Marina Ibrahim, Pierre Pagé, Philippe Demers, Denis Bouchard, Pierre‐Luc Bernier, Nancy Poirier, Emmanuel Moss, Nicolas Durrleman, Hughes Jeanmart, Michel Pellerin, Guillaume Lettre, Nathalie Thorin‐Trescases, Michel Carrier, Eric Thorin   +19 more
wiley   +1 more source