Results 11 to 20 of about 238,146 (360)
Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 542-549, December 2022., 2022 Schematic diagram showing RHAU can bind and unwind the G4 “knots” to modulate embryonic development and post‐natal organ function. Deficiency of RHAU gives rise to embryonic lethality, impaired organogenesis and organ dysfunction. RHAU modulates Nkx2‐5 mRNA and Yap1 mRNA at the post‐transcriptional level and facilitates the transcription of c‐Kit and ...
Chensi Yang +5 more
wiley +1 more source
BioFactors, Volume 48, Issue 6, Page 1226-1249, November/December 2022., 2022 Abstract Ocular allergies are becoming more prevalent as more airborne pollutants, irritants and microbes pervade our environment. Inflammatory and allergic mediators released by dendritic and mast cells within the conjunctiva cause allergic conjunctivitis (AC), a prevalent ocular surface disorder that affects >40% of the world's human population on a ...
Najam A. Sharif
wiley +1 more source
Brazilian Journal of Medical and Biological Research, 2000 The interaction of plasminogen, tissue plasminogen activator (t-PA) and urokinase with a clinical strain of Helicobacter pylori was studied. Plasminogen bound to the surface of H. pylori cells in a concentration-dependent manner and could be activated to
A. Yarzábal +5 more
doaj +1 more source
Roles of tissue plasminogen activator and its inhibitor in proliferative diabetic retinopathy [PDF]
International Journal of Ophthalmology, 2014 AIM:To investigate the role of tissue plasminogen activator (t-PA) and plasminogen activator inhibitor (PAI) in proliferative diabetic retinopathy (PDR) and to discuss the correlations among t-PA, PAI and vascular endothelial growth factor (VEGF ...
Shu-Ling Wu +3 more
doaj +1 more source
Oman Medical Journal, 2013 Objectives: This study was aimed to determine plasma levels of total (TFPI-T) and free (TFPI-F) tissue factor pathway inhibitor, plasminogen activator inhibitor-1 (PAI-1), and tissue plasminogen activator (t-PA) in a cohort of Saudi patients with chronic
Syed Shahid Habib
doaj +1 more source
Plasminogen activators and plasminogen activator inhibitors in endometriosis
Frontiers in Bioscience, 2005 Endometriosis is one of the most frequent benign gynecological diseases that affect women. Little is known about the pathogenesis and etiology of endometriosis, despite the numerous studies performed in this field. Although endometriosis is a benign disease, the endometrial tissue, after attachment to the peritoneum, has the ability to grow and invade ...
Luis A. Ramón +6 more
openaire +4 more sources
Expression in E. coli of finger-domain lacking tissue-type plasminogen activator with high fibrin affinity [PDF]
, 1985 Tissue-type plasminogen activator (t-PA) has a high affinity for fibrin and induces lysis of fibrin (fibrinolysis) on the surface of fibrin without degrading circulating fibrinogen.
Bando, Hiroshi +7 more
core +1 more source
Neuroimaging for differential diagnosis of transient neurological attacks
Brain and Behavior, Volume 12, Issue 12, December 2022., 2022 Abstract Background Rapid yet comprehensive neuroimaging protocols are required for patients with suspected acute stroke. However, stroke mimics can account for approximately one in five clinically diagnosed acute ischemic strokes and the rate of thrombolyzed mimics can be as high as 17%.
Ying Wang, Hao Zha
wiley +1 more source
Proteolytic enzyme and adiponectin receptors as potential targets for COVID-19 therapy
Кардиоваскулярная терапия и профилактика, 2021 The coronavirus disease 2019 (COVID-19) pandemic requires not only the creation of vaccines to prevent the spread of the disease, but also the development of novel drugs aimed at reducing viral load, suppressing an excessive immune response and ...
K. A. Rubina +5 more
doaj +1 more source
Rejuvenation and memory effects in active glasses induced by thermal and active cycling [PDF]
Phys. Rev. Research 6, 023257 (2024), 2023 It has recently been shown that thermal active glasses can display physical aging behavior comparable to that of passive glasses, although there are some notable distinctions due to the intrinsic non-equilibrium nature of active matter. The question whether active disordered materials can also exhibit rejuvenation and memory effects, akin to the ...
arxiv +1 more source