Development and application of global assays of hyper‐ and hypofibrinolysis
Research and Practice in Thrombosis and Haemostasis, 2020 Numerous methods for evaluation of global fibrinolytic activity in whole blood or plasma have been proposed, with the majority based on tissue‐type plasminogen activator (t‐PA) addition to initiate fibrinolysis. We propose that such an approach is useful
Anton Ilich +12 more
doaj +1 more source
Evaluation of coagulation activation after Rhinovirus infection in patients with asthma and healthy control subjects: an observational study [PDF]
, 2014 Background Asthma exacerbations are frequently triggered by rhinovirus infections. Both asthma and respiratory tract infection can activate haemostasis. Therefore we hypothesized that experimental rhinovirus-16 infection and asthmatic airway inflammation
Bel, EHD +12 more
core +4 more sources
Clinical Cardiology, Volume 45, Issue 12, Page 1143-1146, December 2022., 2022 Abstract Background The Clopidogrel and Acetylsalicylic Acid in Bypass Surgery for Peripheral Arterial Disease (CASPAR) trial is the only large, double‐blind, placebo‐controlled trial of dual antiplatelet therapy (DAPT) versus aspirin in patients with peripheral artery disease (PAD) after lower extremity revascularization (LER).
Marc P. Bonaca +9 more
wiley +1 more source
Coexistence of active and hydrodynamic turbulence in two dimensional active nematics [PDF]
, 2022 In active nematic liquid crystals activity is able to drive chaotic spatiotemporal flows referred to as active turbulence. Active turbulence has been characterized through theoretical and experimental work as a low Reynolds number phenomenon. We show that, in two-dimensions, the active forcing alone is able to trigger hydrodynamic turbulence leading to
arxiv +1 more source
Fibrinolysis regulation by platelets retaining plasminogen and tissue-type plasminogen activator on their surface [PDF]
The Ukrainian Biochemical Journal, 2019 Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood.
T. Grinenko +4 more
doaj +1 more source
Interaction of plasminogen and fibrin in plasminogen activation. [PDF]
Journal of Biological Chemistry, 1990 Glu1-, Lys77-, miniplasminogens, kringle 1-3, kringle 1-5A, and kringle 1-5R were able to bind with fibrin, while microplasminogen and kringle 4 did not bind significantly. Kringle 1-5A, but not kringle 1-3, effectively inhibited the binding of Glu1-, Lys77-, and miniplasminogens with fibrin.
Bi-Ing Chang +6 more
openaire +2 more sources
Unusual case of acute coronary syndrome: inferior wall myocardial infarction 19 years young male presented with fever and right ankle cellulites treated with tissue plasminogen activator and its out come [PDF]
, 2017 Unusual case of acute coronary syndrome: inferior wall myocardial infarction in 19yrs young male patient presented with fever and right ankle cellulites with fungal infection, thrombolysis was done with injection tenectaplase a newer tissue plasminogen ...
Das, V. K. +2 more
core +2 more sources
Gene expression of fibrinolytic markers in coronary thrombi
Thrombosis Journal, 2022 Background The fibrinolytic system plays an important role in coronary artery atherothrombosis, and especially circulating plasminogen-activator inhibitor (PAI) type 1 (PAI-1) associates with increased mortality, infarct size and heart failure in ...
Jostein Nordeng +9 more
doaj +1 more source
Active chiral molecules in activity gradients [PDF]
, 2022 While the behavior of active colloidal molecules is well studied by now for a constant activity, the effect of activity gradients is much less understood. Here we explore one of the simplest molecules in activity gradients, namely active chiral dimers composed of two particles with opposite active torques of the same magnitude.
arxiv +1 more source
Systemic effects of tissue plasminogen activator-associated fibrinolysis and its relation to thrombin generation in orthotopic liver transplantation [PDF]
, 1989 Orthotopic liver transplantation is frequently associated with hyperfibrinolysis, the origin and clinical relevance of which is largely unknown. In 20 orthotopic liver transplantations, we studied the occurrence and systemic effects of hyperfibrinolysis.
Bontempo, FA +5 more
core +1 more source