Results 311 to 320 of about 681,261 (380)

Permeable Lung Vasculature Creates Chemoresistant Endothelial Niche by Producing SERPINE1 at Breast Cancer Metastatic Sites

Cancer Science, Volume 116, Issue 6, Page 1604-1615, June 2025.
Vascular permeability is increased by lung metastasis, which correlates with YAP activation in ECs. Activated ECs provide SERPINE1 to neighboring cancer cells to promote chemoresistance and stemness. ABSTRACT Chemotherapy resistance remains a major obstacle for eradicating metastatic cancer cells in distant organs. We identified that endothelial cells (
Tsunaki Hongu, Sarenqiqige, Shandan, Hirokazu Kusunoki, Akihiko Ishimura, Takeshi Suzuki, Thordur Oskarsson, Noriko Gotoh   +7 more
wiley   +1 more source

Use of balloon angioplasty for patients with intracranial large atherosclerotic acute ischemic stroke and cerebral cavernous malformation: a case report. [PDF]

Front Neurol
Wang Y, Wang T, Liang J.
europepmc   +1 more source

Obesity‐related glomerulopathy: How it happens and future perspectives

Diabetic Medicine, Volume 42, Issue 6, June 2025.
Abstract Obesity‐related glomerulopathy (ORG) is an emerging complication of excess adiposity. Its incidence rises alongside the obesity pandemic. Up to 40% of individuals can be affected by ORG, irrespective of the status of glomerular filtration rate and albuminuria.
Jian‐Wen Samuel Lee‐Boey, Jia‐Kai Tan, Zhan‐Foong Lim, Francesco Zaccardi, Kamlesh Khunti, Majid Ezzati, Edward W. Gregg, Lee‐Ling Lim   +7 more
wiley   +1 more source

MiR-145-5p inhibits proliferation of hepatocellular carcinoma, acting through PAI-1. [PDF]

Am J Transl Res
Li J, Ma J.
europepmc   +1 more source

Metformin use in women with polycystic ovary syndrome (PCOS): Opportunities, benefits, and clinical challenges

Diabetes, Obesity and Metabolism, Volume 27, Issue S3, Page 31-47, June 2025.
Abstract Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is characterised by hormonal imbalances such as hyperandrogenism and anovulation, metabolic abnormalities including
Saeede Saadati, Taitum Mason, Rasoul Godini, Eszter Vanky, Helena Teede, Aya Mousa   +5 more
wiley   +1 more source

Identification of key genes and diagnostic biomarkers for peripheral atherosclerosis: A multi-omics approach. [PDF]

Medicine (Baltimore)
Huang L, Li H, Lin Q.
europepmc   +1 more source

Therapeutic options for human papillomavirus‐positive tonsil and base of tongue cancer

Journal of Internal Medicine, Volume 297, Issue 6, Page 608-629, June 2025.
Abstract The incidences of human papillomavirus‐positive (HPV+) tonsillar and base tongue squamous cell carcinomas (TSCC and BOTSCC) have increased in recent decades. Notably, HPV+ TSCC and BOTSCC have a significantly better prognosis than their HPV‐negative counterparts when treated with current surgical options, radiotherapy, or intensified ...
Mark Zupancic, Ourania N. Kostopoulou, Linda Marklund, Tina Dalianis   +3 more
wiley   +1 more source

Evaluation of six novel biomarkers for predicting recurrence of non-muscle invasive bladder cancer after endoscopic resection- a prospective observational study. [PDF]

World J Urol
Bardowska K, Krajewski W, Kołodziej A, Kościelska-Kasprzak K, Bartoszek D, Żabińska M, Chorbińska J, Kubacki F, Królicki T, Krajewska M, Szydełko T, Kamińska D.   +11 more
europepmc   +1 more source

Recombinant Plasminogen Activator of the Sandworm (Perinereis aibuhitensis) Expression in Escherichia coli. [PDF]

Bioengineering (Basel)
Song T, Diao X, Cheng J, Man Y, Chen B, Zhang H, Wu W.   +6 more
europepmc   +1 more source

Hyperperfusion Syndrome Following Tissue Plasminogen Activator Administration: A Case Report with Radiological Evidence. [PDF]

J Korean Soc Radiol
Koh NH, Kim SS, Oh HY, Kim S, Jang JW.
europepmc   +1 more source