Results 31 to 40 of about 238,146 (360)
European Journal of Immunology, Volume 53, Issue 1, January 2023., 2023 Neutrophils play a role in the immunopathology SARS‐CoV‐2 infection by triggering the formation of NETs, producing cytokines including interleukin‐8 (CXCL8), and mediating the recruitment of other immune cells to regulate inflammation, which can lead to ARDS.
Maria Candida Cesta +8 more
wiley +1 more source
Safety and efficacy of tissue-type plasminogen activator produced by recombinant DNA technology [PDF]
, 1987 Because of its enhanced activation of plasminogen in association with fibrin compared with free plasminogen, tissue-type plasminogen activator (t-PA) evoked excitement as a potentially useful pharmacologic activator of the fibrinolytic system.
Sobel, Burton E.
core +1 more source
Hepatology, EarlyView., 2022 KAT7‐acetylated and cytoplasm‐translocated G‐protein GαS enhances IL‐6 effect and drives HCC progenitor cell progression. Abstract Background and Aims Hepatocarcinogenesis goes through HCC progenitor cells (HcPCs) to fully established HCC, and the mechanisms driving the development of HcPCs are still largely unknown.
Ye Zhou +15 more
wiley +1 more source
Journal of Traditional and Complementary Medicine, 2016 Fagonia arabica (FA) possesses a thrombolytic property which has been earlier reported in our laboratory. Current study was undertaken to investigate the effect of aqueous extract of FA on thrombin-induced tissue plasminogen activator (t-PA) and ...
Prutha D. Aloni +8 more
doaj +1 more source
Activation Functions: Dive into an optimal activation function [PDF]
arXiv, 2022 Activation functions have come up as one of the essential components of neural networks. The choice of adequate activation function can impact the accuracy of these methods. In this study, we experiment for finding an optimal activation function by defining it as a weighted sum of existing activation functions and then further optimizing these weights ...
arxiv
Effect of dsRNA on Mesangial Cell Synthesis of Plasminogen Activator Inhibitor Type 1 and Tissue Plasminogen Activator [PDF]
, 2009 Background/Aims: Viral infections are a major problem worldwide and many of them are complicated by virally induced glomerulonephritides. Progression of kidney disease to renal failure is mainly attributed to the development of renal fibrosis ...
Merkle, Monika +4 more
core +1 more source
Journal of Functional Foods, 2022 Thrombosis is a severe health care issue and one of the leading causes of death globally. Since presently used drugs have a number of limitations, safe and effective thrombolytic agents are still needed.
Yiping Tang +9 more
doaj
Growth and fibrinolytic parameters of human umbilical vein endothelial cells seeded onto cardiovascular grafts [PDF]
, 1995 It was the aim of this study to investigate possible effects of biomaterials used to produce vascular grafts on the fibrinolytic system of endothelial cells.
Binder, Bernd R. +2 more
core +1 more source
Research in Pharmaceutical Sciences, 2019 Reteplase (recombinant plasminogen activator, r-PA) is a thrombolytic agent recombined from tissue-type plasminogen activator (t-PA), which has several prominent features such as strong thrombolytic ability and E. coli expressibility.
Hooria Seyedhosseini Ghaheh +4 more
doaj +1 more source
Life, 2023 (1) Background: Cancer treatment, including chemotherapy, endocrine therapy, targeted therapy and radiotherapy, has been identified as an important independent risk factor for venous thromboembolism in cancer patients.
Katarzyna Wrzeszcz +3 more
doaj +1 more source