Results 41 to 50 of about 238,146 (360)
The random first-order transition theory of active glass in the high-activity regime [PDF]
arXiv, 2021 Dense active matter, in the fluid or amorphous-solid form, has generated intense interest as a model for the dynamics inside living cells and multicellular systems. An extension of the random first-order transition theory (RFOT) to include activity was developed, whereby the activity of the individual particles was added to the free energy of the ...
arxiv
Journal of Clinical Apheresis, Volume 37, Issue 6, Page 534-543, December 2022., 2022 Abstract Introduction Therapeutic plasma exchange (TPE) is used for several chronic conditions with little evidence on the efficacy and safety of different choice of replacement fluid. Measurement of haemostasis, particularly in vitro thrombin generation, could play a role in determining the immediate efficacy of different fluid replacement.
Ruchika Kohli +6 more
wiley +1 more source
Activity gradients in two- and three-dimensional active nematics [PDF]
arXiv, 2022 We numerically investigate how spatial variations of extensile or contractile active stress affect bulk active nematic systems in two and three dimensions. In the absence of defects, activity gradients drive flows which re-orient the nematic director field and thus act as an effective anchoring force.
arxiv
Expression of a Novel Chimeric Truncated t-PA in CHO Cells Based on in Silico Experiments [PDF]
, 2010 Tissue plasminogen activator (t-PA) is one of the fibrin-specific serine proteases that play a crucial role in the fibrinolytic system. The rapid clearance of the drug from the circulation, caused by its active uptake in the liver, has lead to ...
Adeli, Ahmad +9 more
core +3 more sources
The Journal of Clinical Pharmacology, Volume 63, Issue 2, Page 197-209, February 2023., 2023 Abstract The pharmacokinetics (PK) of tenecteplase in patients with acute ischemic stroke has not been extensively studied. This study aimed to describe PK characteristics of tenecteplase in patients with acute myocardial infarction (AMI) using a population PK approach and to assess applicability of the findings to patients with acute ischemic stroke ...
Fei Tang +7 more
wiley +1 more source
Pathogen activators of plasminogen [PDF]
Journal of Thrombosis and Haemostasis, 2015 Group A streptococci (GAS) express soluble and surface-bound virulence factors. Secreted streptokinase (SK) allelic variants exhibit varying abilities to activate host plasminogen (Pg), and GAS pathogenicity is associated with Pg activation and localization of the resulting plasmin (Pm) on the bacterial surface to promote dissemination.
Paul E. Bock +2 more
openaire +3 more sources
Low‐field MRI: Clinical promise and challenges
Journal of Magnetic Resonance Imaging, Volume 57, Issue 1, Page 25-44, January 2023., 2023 Modern MRI scanners have trended toward higher field strengths to maximize signal and resolution while minimizing scan time. However, high‐field devices remain expensive to install and operate, making them scarce outside of high‐income countries and major population centers.
Thomas Campbell Arnold +3 more
wiley +1 more source
Histone deacetylase inhibition enhances tissue plasminogen activator release capacity in atherosclerotic man. [PDF]
PLoS ONE, 2015 The expression of the tissue plasminogen activator (t-PA) gene appears to be under epigenetic control and can be affected by histone deacetylation inhibition.
Kristina Svennerholm +8 more
doaj +1 more source
The Association of the Metabolic Syndrome with PAI-1 and t-PA Levels [PDF]
, 2011 Background. We used a random sample (n = 2, 495) from the population-based Prevention of Renal and Vascular End-stage Disease (PREVEND) study population to examine the association of the metabolic syndrome (Met S) with plasminogen activator inhibitor ...
Asselbergs, Folkert W. +6 more
core +4 more sources
Secretory activity of the coronary artery endothelial cells in conditions of the peritoneal dialysis
Renal Failure, 2022 Introduction Endothelial dysfunction is frequent in patients treated with peritoneal dialysis and may lead to cardiac complications. We evaluated the effect of effluent dialysates and serum on the function of coronary artery endothelial cells (CAEC ...
Monika Misian +2 more
doaj +1 more source