Results 71 to 80 of about 1,692,892 (304)

Mapping the evolution of mitochondrial complex I through structural variation

open access: yesFEBS Letters, EarlyView.
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin   +2 more
wiley   +1 more source

REDD1 Is Essential for Optimal T Cell Proliferation and Survival. [PDF]

open access: yesPLoS ONE, 2015
REDD1 is a highly conserved stress response protein that is upregulated following many types of cellular stress, including hypoxia, DNA damage, energy stress, ER stress, and nutrient deprivation.
Emma L Reuschel   +6 more
doaj   +1 more source

T-stress evaluation for slightly curved crack using perturbation method

open access: yesInternational Journal of Solids and Structures, 2008
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
Chen, Y.Z., Lin, X.Y., Wang, Z.X.
openaire   +1 more source

Trends to determine fracture intiation and propagation of a pipe under service pressure [PDF]

open access: yes, 2015
A fracture toughness transferability curve has been established for the X52 pipe steels described by a linear relationship between the notch critical stress intensity factor and the average value of T stress over the opening stress distribution.
Azari, Z., Ben, M., Capelle, J.
core  

The 1/r singularity in weakly nonlinear fracture mechanics

open access: yes, 2009
Material failure by crack propagation essentially involves a concentration of large displacement-gradients near a crack's tip, even at scales where no irreversible deformation and energy dissipation occurs. This physical situation provides the motivation
Ariel Livne   +25 more
core   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

open access: yesFEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Evaluation of multiaxial low cycle fatigue life under non-proportional loading considering effect of mean strain (Loading simulated thermal fatigue due to temperature fluctuation in junction piping)

open access: yesNihon Kikai Gakkai ronbunshu, 2020
In a pressure vessel, a heat exchanger and a junction piping where cold and hot water are mixed, temperature fluctuation yields multiaxial stress and random amplitude loading conditions.
Takahiro MORISHITA   +2 more
doaj   +1 more source

T -stress effects on crack deflection: Straight vs. curved crack advance

open access: yesEuropean Journal of Mechanics - A/Solids, 2016
zbMATH Open Web Interface contents unavailable due to conflicting licenses.
SAPORA, ALBERTO GIUSEPPE   +2 more
openaire   +3 more sources

A numerical analysis of the relation between CTOD and fatigue crack growth [PDF]

open access: yes, 2016
El cálculo de la vida a fatiga durante la etapa de propagación de la grieta se suele realizar relacionando da/dN con ΔK. Sin embargo, la influencia que en estos análisis tiene el parámetro ΔK debe recaer en algún otro parámetro no lineal cercano al ...
Antunes, F.V.   +2 more
core  

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