β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Different roles of T-type calcium channel isoforms in hypnosis induced by an endogenous neurosteroid epipregnanolone. [PDF]
Coulter I +8 more
europepmc +1 more source
Electrophysiological Characterization of T-Type Calcium Channels in Central Medial Nucleus of the Rat Thalamus [PDF]
Tamara Timić Stamenić +1 more
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The effect of temperature controllers that are commonly used in freeze‐casting is investigated in this work. Temperature controllers are observed to generate a voltage in the slurry. Microstructural alignment and ultimate compressive strength data show this voltage to interfere with the ability to align the microstructure using magnetic fields ...
Maddie A. Schmitz, Steven E. Naleway
wiley +1 more source
Cyclic Peptides as T-Type Calcium Channel Blockers: Characterization and Molecular Mapping of the Binding Site. [PDF]
Depuydt AS +8 more
europepmc +1 more source
A Recurrent Mutation in CACNA1G Alters Cav3.1 T-Type Calcium-Channel Conduction and Causes Autosomal-Dominant Cerebellar Ataxia [PDF]
Marie Coutelier +14 more
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T-type channel interactions with calcium activated potassium channels
In this thesis we investigate the relationship between calcium activated potassium channels (KCa1.1, KCa3.1) and low voltage activated calcium channels (Cav3). KCa1.1 are known to participate in neuronal excitability through their contribution to action potential repolarization and generation of fast afterhyperpolarizing potentials (AHPs) whereas KCa3 ...
openaire +2 more sources
This article describes the preparation and characterization of poly(ε‐caprolactone) electrospun composite fibers incorporating sol‐gel‐derived bioactive glass particles doped with B and Cu. Scanning electron microscopy, energy‐dispersive X‐ray spectroscopy, Fourier‐transform infrared spectroscopy, contact angle, acellular bioactivity, mechanical and ...
Elisa Piatti +5 more
wiley +1 more source
Nickel Block of Three Cloned T-Type Calcium Channels: Low Concentrations Selectively Block α1H [PDF]
Jung‐Ha Lee +3 more
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An idea of designing novel sensors is proposed by creating appropriate Schottky barriers and vacancies between isomorphous Core‐CuOii/ Shell‐CuOi secondary microspheres and enhancing catalytic and spill‐over effects, and electronegativity via spontaneous biphasic separation, self‐assembly, and trace‐Ni‐doping.
Bala Ismail Adamu +8 more
wiley +1 more source

