Results 201 to 210 of about 434,844 (347)

Inhibition of T-Type calcium channels in mEC layer II stellate neurons reduces neuronal hyperexcitability associated with epilepsy

, 2019
Aradhya Nigam, Nicholas J. Hargus, Bryan S. Barker, Matteo Ottolini, James A. Hounshell, Edward H. Bertram, Edward Perez‐Reyes, Manoj K. Patel   +7 more
openalex   +2 more sources

Lipid Nanoparticles for the Delivery of CRISPR/Cas9 Machinery to Enable Site‐Specific Integration of CFTR and Mutation‐Agnostic Disease Rescue

Advanced Functional Materials, EarlyView.
Lipid nanoparticles (LNPs) are optimized to co‐deliver Cas9‐encoding messenger RNA (mRNA), a single guide RNA (sgRNA) targeting the endogenous cystic fibrosis transmembrane conductance regulator (CFTR) gene, and homologous linear double‐stranded donor DNA (ldsDNA) templates encoding CFTR.
Ruth A. Foley, Paul G. Ayoub, Vrishti Sinha, Colin Juett, Alicia Sanoyca, Emily C. Duggan, Lindsay E. Lathrop, Priyanka Bhatt, Kevin Coote, Beate Illek, Brigitte N. Gomperts, Donald B. Kohn, Steven J. Jonas   +12 more
wiley   +1 more source

Norepinephrine Upregulates T-Type Calcium Channels in Rat Pinealocytes [PDF]

, 2015
Haijie Yu, Jong Bae Seo, Seung‐Ryoung Jung, Duk‐Su Koh, Bertil Hille   +4 more
openalex   +1 more source

T-Type Calcium Channels: A Potential Novel Target in Melanoma [PDF]

, 2020
Carla Barceló, Pol Sisó, Óscar Maiques, Inés de la Rosa, Manuel Martín González, Anna Macià   +5 more
openalex   +1 more source

Copper‐based Materials for Photo and Electrocatalytic Process: Advancing Renewable Energy and Environmental Applications

Advanced Functional Materials, EarlyView.
Cu‐based catalysts as a cornerstone in advancing sustainable energy technologies are fully reviewed in this manuscript, highlighting their potential in photo‐ and electrocatalysis. It includes metallic copper, copper oxides, copper sulfides, copper halide perovskites, copper‐based metal–organic frameworks (MOFs), and covalent organic frameworks (COFs),
Jéssica C. de Almeida, Yanjie Wang, Thais A. Rodrigues, Paulo H. H. Nunes, Vagner R. de Mendonça, Paulo H. E. Falsetti, Leticia V. Savazi, Tao He, Alexandra V. Bardakova, Aida V. Rudakova, Jie Tian, Alexei V. Emeline, Osmando F. Lopes, Antonio Otavio T. Patrocínio, Jia Hong Pan, Caue Ribeiro, Detlef W. Bahnemann   +16 more
wiley   +1 more source

Application, Development History, and Current Status of T-Type Calcium Channel Inhibitors in Pain Treatment [PDF]

Fu‐I Lu, Wanbin Huang, Chunping Xu, Yanjie Zhou, Haoye Qin, Zheman Xiao   +5 more
openalex   +1 more source

Prospects of Electric Field Control in Perpendicular Magnetic Tunnel Junctions and Emerging 2D Spintronics for Ultralow Energy Memory and Logic Devices

Advanced Functional Materials, EarlyView.
Electric control of magnetic tunnel junctions offers a path to drastically reduce the energy requirements of the device. Electric field control of magnetization can be realized in a multitude of ways. These mechanisms can be integrated into existing spintronic devices to further reduce the operational energy.
Will Echtenkamp, Brahmdutta Dixit, Yifei Yang, Deyuan Lyu, Thomas Peterson, Qi Jia, Yu‐Chia Chen, Jian‐Ping Wang   +7 more
wiley   +1 more source

Automated gait analysis indicates efficacy of T-type calcium channel inhibition for mitigation of disrupted calcium signalling in an SCA5 mouse model. [PDF]

Sci Rep
Suminaite D, Talib NF, Pettegree SJ, Tan HCG, Odey YL, Perkins EM, Lyndon AR, Skehel PA, Jackson M.   +8 more
europepmc   +1 more source

Synthesis and biological evaluation of 1-(2-hydroxy-3-phenyloxypropyl)piperazine derivatives as T-type calcium channel blockers

, 2013
Jung‐Eun Park, Wan Keun Ji, Jae Wan Jang, Ae Nim Pae, Kee-Hyun Choi, Ki Hang Choi, Jahyo Kang, Eun Joo Roh   +7 more
openalex   +1 more source

T-type calcium channel Cav3.2 deficient mice show elevated anxiety, impaired memory and reduced sensitivity to psychostimulants [PDF]

, 2014
Giuseppe Gangarossa, Sophie Laffray, Emmanuel Bourinet, Emmanuel Valjent   +3 more
openalex   +1 more source