Chronic Trypanosoma cruzi infection potentiates adipose tissue macrophage polarization toward an anti-inflammatory M2 phenotype and contributes to diabetes progression in a diet-induced obesity model [PDF]
, 2016 Chronic obesity and Chagas disease (caused by the protozoan Trypanosoma cruzi) represent serious public health concerns. The interrelation between parasite infection, adipose tissue, immune system and metabolism in an obesogenic context, has not been ...
Andrada, Marta Cecilia +8 more
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Sylvatic focus of American Trypanosomiasis in the State of Morelos, Mexico
Revista de Biología Tropical, 2001 Wild vectors and reservoir hosts of Trypanosoma cruzi were surveyed from February 1993 to June 1994 in Ticumán (18°46’N, 99°07’W), Mexico (Deciduous Tropical Forest). Direct faeces examination showed that 87% of Triatoma pallidipennis hosted the parasite;
Juan Carlos Villegas-García +1 more
doaj
New compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites:an open resource [PDF]
, 2015 Using whole-cell phenotypic assays, the GlaxoSmithKline high-throughput screening (HTS) diversity set of 1.8 million compounds was screened against the three kinetoplastids most relevant to human disease, i.e.
Alonso-Padilla, Julio +20 more
core +3 more sources
Alteration of Migration and Maturation of Dendritic Cells and T-Cell Depletion in the Course of Experimental Trypanosoma cruzi Infection [PDF]
, 2003 Damien Chaussabel +8 more
openalex +1 more source
Journal of Parasitology Research, 2009 Phylogenetic studies of Trypanosoma cruzi have identified the existence of two groups: T. cruzi I and T. cruzi II. There are aspects that still remain unknown about the genetic variability within the T. cruzi I group. Given its epidemiological importance,
Claudia Herrera +6 more
doaj +1 more source
Inserção de DNA de Trypanosoma cruzi no genoma de célula hospedeira de mamífero por meio de infecção
Revista da Sociedade Brasileira de Medicina Tropical, 1991 Observamos a cromatina deformas amastigotas de T. cruzi associada a cromossomos de macrófagos metafásicos obtidos em diversos períodos da infecção aguda.
Antonio R.L. Teixeira +3 more
doaj
Trypanosoma cruzi infection in mammals in Florida: New insight into the transmission of T. cruzi in the southeastern United States. [PDF]
Int J Parasitol Parasites Wildl, 2023 Torhorst CW +6 more
europepmc +1 more source
The Trypanosoma cruzi Flagellum Is Discarded via Asymmetric Cell Division following Invasion and Provides Early Targets for Protective CD8+ T Cells [PDF]
, 2014 Samarchith P. Kurup, Rick L. Tarleton
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Review of Chagas Disease and Treatment Obstacles to Eradication [PDF]
, 2019 The World Health Organization and the Center for Disease Control reports Chagas disease, or American trypanosomiasis, as a major neglected tropical disease prevalent in 21 endemic Latin American countries.
Sherman, Emily
core +1 more source
Impact of Laboratory-Adapted Intracellular Trypanosoma cruzi Strains on the Activity Profiles of Compounds with Anti-T. cruzi Activity. [PDF]
Microorganisms, 2023 Sykes ML, Kennedy EK, Avery VM.
europepmc +1 more source