Results 131 to 140 of about 12,032,280 (304)
Journal of Veterinary Internal MedicineTrypanosoma cruzi infection in dogs can cause heart failure and sudden death with few treatment options available. A litter of 4 dogs living in a T cruzi endemic area were randomized to prophylaxis and nonprophylaxis groups as part of a study evaluating ...
Sukjung Lim +4 more
doaj +1 more source
Natural selection and genetic variation in a promising Chagas disease drug target: Trypanosoma cruzi trans-sialidase [PDF]
, 2017 Rational drug design is a powerful method in which new and innovative therapeutics can be designed based on knowledge of the biological target aiming to provide more efficacious and responsible therapeutics.
Gallant, Joseph P.
core +1 more source
Identification of Trypanosoma cruzi Polyamine Transport Inhibitors by Computational Drug Repurposing [PDF]
, 2019 Trypanosoma cruzi is the causative agent of Chagas disease, a parasitic infection endemic in Latin America. In T. cruzi the transport of polyamines is essential because this organism is unable to synthesize these compounds de novo.
Martínez Sayé, Melisa Soledad +5 more
core +1 more source
Meiotic sex in Chagas disease parasite Trypanosoma cruzi
Nature Communications, 2019 Genetic exchange enables parasites to rapidly transform disease phenotypes and exploit new host populations. Trypanosoma cruzi, the parasitic agent of Chagas disease and a public health concern throughout Latin America, has for decades been presumed to ...
P. Schwabl +8 more
semanticscholar +1 more source
Effects of the alarm pheromone on Triatoma pallidipennis behaviour
Physiological Entomology, EarlyView.T. pallidipennis performs behavioural acts in response to volatiles emitted by mechanically disturbed conspecifics. T. pallidipennis shows a repellent response when exposed to volatiles emitted by mechanically disturbed conspecifics. Isobutyric and propanoic acids can be used as repellents of T. pallidipennis. Abstract Adults of some Triatomine species,
Claudia I. Albores‐Flores +5 more
wiley +1 more source
Detection of Trypanosoma cruzi in white-eared opossums (Didelphis albiventris) from Canoinhas, Santa Catarina State, Brazil [PDF]
Revista Brasileira de Parasitologia VeterináriaOpossums are synanthropic animals that participate in the zoonotic transmission cycles. Chagas disease, a neglected tropical disease caused by Trypanosoma cruzi, affects many domestic and wild animals and humans worldwide.
Giane Helenita Pontarolo +10 more
doaj +1 more source
The burden of congenital Chagas disease and implementation of molecular diagnostic tools in Latin America [PDF]
, 2018 It is estimated that between 8000 and 15 000 Trypanosoma cruzi infected babies are born every year to infected mothers in Chagas disease endemic countries. Currently, poor access to and performance of the current diagnostic algorithm, based on microscopy
Cruz, Israel +7 more
core +1 more source
Scientific Reports, 2018 Trypanosoma cruzi is the agent of Chagas disease, transmitted by hematophagous triatomine vectors. Establishing transmission cycles is key to understand the epidemiology of the disease, but integrative assessments of ecological interactions shaping ...
Eric Dumonteil +6 more
semanticscholar +1 more source
Transfusion Medicine, EarlyView.Abstract Background The COVID‐19 pandemic posed a worldwide challenge for blood services. We aimed to evaluate the impact of the COVID‐19 pandemic on blood donations and blood discards resulting from screening tests for transfused‐transmitted infections (TTIs) in a Brazilian metropolitan.
Laiane da Silva Santos +5 more
wiley +1 more source
Tropical Medicine &International Health, EarlyView.ABSTRACT Background Chagas disease, caused by Trypanosoma cruzi, remains a significant public health challenge in Latin America, with diagnostic limitations hindering control efforts. Aim Our study aimed to assess the diagnostic performance of four chimeric recombinant T.
Ângelo Antônio Oliveira Silva +12 more
wiley +1 more source