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1980
Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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Publisher Summary Trypanosoma cruzi (T. cruzi), the causative agent of Chagas disease, is a digenetic trypanosomatid, which circulates in the bloodstream of the vertebrate host as trypomastigotes and has an obligatory intracellular phase in which the parasite multiplies as amastigotes, which differentiate into trypomastigotes.
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Experimental Parasitology, 1989
Chromosome-sized DNA molecules from Trypanosoma cruzi clone Dm 28c were analyzed and compared with other T. cruzi strains and monogenetic trypanosomatids by orthogonal field alteration gel electrophoresis. The results showed that T. cruzi Dm 28c displays at least 18 chromosomes ranging from 550 to more than 1500 kb and that in general the ...
Aymerich, Stephane, S., Goldenberg, S.
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Chromosome-sized DNA molecules from Trypanosoma cruzi clone Dm 28c were analyzed and compared with other T. cruzi strains and monogenetic trypanosomatids by orthogonal field alteration gel electrophoresis. The results showed that T. cruzi Dm 28c displays at least 18 chromosomes ranging from 550 to more than 1500 kb and that in general the ...
Aymerich, Stephane, S., Goldenberg, S.
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The Cytostome of Trypanosoma cruzi and T. conorhini*
The Journal of Protozoology, 1969SYNOPSIS. A cytostome is described in culture forms and in intracellular stages of Trypanosoma cruzi and in culture forms of T. conorhini. The organelle opens into the flagellar pocket or close to it and runs deeply into the cell.
Regina Vugman Milder, Maria P. Deane
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On the chromatin structure of Trypanosoma cruzi
Molecular and Biochemical Parasitology, 1980The chromatin structure of Trypanosoma cruzi was investigated. It was found that, as in other eukaryotes, the chromatin is organized in repeating units, the nucleosomes containing about 200 base pairs of DNA associated with histones. While there is no difference in the DNA size in nucleosomes from T.
Cezar Martins de Sá +2 more
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Chapter 7 Glycobiology of Trypanosoma cruzi
2009Abstract The glycobiology of Trypanosoma cruzi, the causative agent of Chagas' disease, has contributed significantly to the identification of target enzymes responsible for the construction of unique cell‐surface molecules. The authors discuss the structure of glycoinositolphospholipids, both free and as protein anchors in T. cruzi.
Rosalía Agusti, Rosa M. de Lederkremer
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The Development of Trypanosoma cruzi in Triatominae
Parasitology Today, 2000Trypanosoma cruzi multiplies and differentiates in the digestive tract of triatomine insects. These insects ingest an enormous amount of blood, with ingestion followed very rapidly by a strong diuresis, slow digestion and occasionally long periods of starvation.
Günter A. Schaub, Astrid H. Kollien
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The γ-glutamyltranspeptidase of Trypanosoma cruzi
Comparative Biochemistry and Physiology Part B: Comparative Biochemistry, 1987Trypanosoma cruzi epimastigotes show gamma-glutamyltranspeptidase activity which has characteristics significantly different than the mammalian enzyme. The protozoan enzyme is localized in the cytosolic fraction, it has a Km of 1.6 mM and a Vmax of 17.4 nmol/min/mg protein with L-gamma-glutamyl-p-nitroanilide as gamma-glutamyl donor, and an optimun pH ...
Yolanda Repetto +3 more
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Acta tropica, 1986
Anti-T. dionisii and anti-T. vespertilionis monoclonal antibodies secreted by 17 hybridoma clones were tested against various strains of T. dionisii, T. vespertilionis, T. cruzi and T. cruzi marinkellei. Strain and species specific antigens were detected for the homologous immunizing strains.
K, Petry, T, Baltz, J, Schottelius
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Anti-T. dionisii and anti-T. vespertilionis monoclonal antibodies secreted by 17 hybridoma clones were tested against various strains of T. dionisii, T. vespertilionis, T. cruzi and T. cruzi marinkellei. Strain and species specific antigens were detected for the homologous immunizing strains.
K, Petry, T, Baltz, J, Schottelius
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Characterization of Trypanosoma cruzi telomerase
Acta Tropica, 2011High telomerase activity is always associated with actively dividing cells, however the detection of this activity in dividing Leishmania and Trypanosoma cruzi cells has always been disappointingly low. Recently, we have found that Leishmania major telomerase activity can be activated by heat, which combined with dilutions of the nuclear extracts ...
Riward Campelo +2 more
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Molecular diagnosis of Trypanosoma cruzi
Acta Tropica, 2018Chagas disease, caused by the kinetoplastid protozoan Trypanosoma cruzi, affects millions of people, most of them neglected populations. The different phases of the disease, the transmission mode and the high genetic variability of the parasite determine that molecular detection methods display different degree of success.
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