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Distribution of Trichinella spiralis, Trichinella britovi, and Trichinella pseudospiralis in the Diaphragms and T. spiralis and T. britovi in the Tongues of Experimentally Infected Pigs. [PDF]

Front Vet Sci, 2021
There is little or even no data in the global literature on the distribution of different species of Trichinella in the individual parts of the diaphragms and tongues in infected pigs. This is of particular importance from the food safety point of view and for the conduct of routine testing of pig carcasses for Trichinella as well as epidemiological ...
Gondek M, Knysz P, Pyz-Łukasik R, Łukomska A, Kuriga A, Pomorska-Mól M.   +5 more
europepmc   +5 more sources

The neuroprotective potential of curcumin on T. Spiralis infected mice. [PDF]

BMC Complement Med Ther
Abstract Background Trichinella spiralis can affect the brain by inducing inflammatory and vascular changes. Drug management with the antiparasitic drug albendazole can be enhanced by natural compounds such as curcumin.
Abdeltawab MS, Abdel-Shafi IR, Aboulhoda BE, Mahfoz AM, Hamed AM.   +4 more
europepmc   +4 more sources

Trichinella spiralis infection remodels intestinal neurotransmitter metabolism during LPS-induced systemic inflammation [PDF]

Food and Waterborne Parasitology
Parasitic helminths can modulate host inflammatory responses, but whether this regulation involves remodeling of the intestinal neurochemical environment remains unclear.
Ruohang Sun, Yi Liu, Qingbo Lv, Kaimeng Shang, Nuo Xu, Mingfei Sun, Mingyuan Liu, Zhuangzhi Zhang, Xiaolei Liu, Xuemin Jin   +9 more
doaj   +2 more sources

First report of T. spiralis in a wolf in Italy: An increasing health concern? [PDF]

Food Waterborne Parasitol
Trichinella spiralis is a zoonotic nematode parasite of worldwide distribution. It is present in Europe with important foci, particularly in Eastern countries and Spain. This species is generally associated with a domestic cycle that involves primarily pigs.
Marucci G, Raso C, Borgogni E, Celani F, Tartarelli I, Cherchi S, Di Giambattista A, Calderini P, Casulli A.   +8 more
europepmc   +4 more sources

S100a4 mediated peritoneal B1 lymphocytes play a critical role in host protection against helminth infection [PDF]

Cell Communication and Signaling
Background Trichinellosis is a globally prevalent parasitic disease caused by infection of Trichinella spiralis. B1 cells are critically involved in immune defense against multiple parasitic infections, yet their functional role in trichinellosis remains
Fei Guan, Xi Luo, Yanmei Huang, Jiang Chang, Ju Liu, Wenwen Zheng, Jinyuan Zhang, Yiyan Gong, Heng Gu, Yi Wang, Yonggui Wu, Wenqi Liu, Jiahui Lei, Chaohong Liu   +13 more
doaj   +2 more sources

Extracellular vesicles derived from Trichinella Spiralis larvae promote the polarization of macrophages to M2b type and inhibit the activation of fibroblasts

Frontiers in Immunology, 2022
Trichinella spiralis (T. spiralis) is a globally distributed food-borne parasite that can coexist with the host for a long time after infection. Trichinella-derived secretions can regulate the immune response and fibroblasts of the host, but the specific
Ji Wu, Yao Liao, Yao Liao, Yao Liao, Dinghao Li, Dinghao Li, Dinghao Li, Zifeng Zhu, Zifeng Zhu, Zifeng Zhu, Lichao Zhang, Lichao Zhang, Lichao Zhang, Zhongdao Wu, Zhongdao Wu, Zhongdao Wu, Ping He, Lifu Wang   +17 more
doaj   +1 more source

Effects of Trichinella spiralis and its excretory/secretory products on autophagy of host muscle cells in vivo and in vitro.

PLoS Neglected Tropical Diseases, 2021
Trichinella spiralis (T. spiralis) is a widely distributed pathogenic microorganism that causes trichinellosis, a disease that has the potential of causing severe harm to their host.
Xiaoxiang Hu, Xiaolei Liu, Xue Bai, Li Yang, Jing Ding, Xuemin Jin, Chen Li, Yulu Zhang, Yanfeng Li, Yong Yang, Mingyuan Liu   +10 more
doaj   +1 more source

RNAi-mediated silencing of Trichinella spiralis glutaminase results in reduced muscle larval infectivity

Veterinary Research, 2021
Trichinella spiralis is an important foodborne parasitic nematode distributed worldwide that infects humans and animals. Glutaminase (GLS) is an important gene in the glutamine-dependent acid resistance (AR) system; however, its role in T.
Yuan Gao, Xiaoqing Meng, Xiao Yang, Shi Meng, Caixia Han, Xiaoyun Li, Shuang Wang, Wei Li, Mingxin Song   +8 more
doaj   +1 more source

Vaccines as a Strategy to Control Trichinellosis

Frontiers in Microbiology, 2022
Trichinellosis caused by Trichinella spiralis is a worldwide food-borne parasitic zoonosis. Several approaches have been performed to control T. spiralis infection, including veterinary vaccines, which contribute to improving animal health and increasing
Bin Tang, Jian Li, Tingting Li, Tingting Li, Tingting Li, Yiting Xie, Wei Guan, Yanqing Zhao, Shuguo Yang, Mingyuan Liu, Daoxiu Xu   +10 more
doaj   +1 more source

Preexisting Trichinella spiralis infection attenuates the severity of Pseudomonas aeruginosa-induced pneumonia.

PLoS Neglected Tropical Diseases, 2022
BackgroundA range of helminth species involve the migration of developing larvae through the lung and establish chronic infections in the host that include potent immune regulatory effects.
Shao Rong Long, Wen Xuan Shang, Miao Jiang, Jing Fei Li, Ruo Dan Liu, Zhong Quan Wang, Hualei Sun, Jing Cui   +7 more
doaj   +1 more source