Results 91 to 100 of about 10,181,390 (213)

HO and PD98059 alleviated intestinal inflammation caused by T. spiralis infection.

open access: yes
A and B: HO and PD98059 inhibited and abrogated the elevated transcription level of pro-inflammatory cytokines (TNF-α and IL-1β) caused by T. spiralis infection.
Xi Zhang (83736)   +9 more
core   +1 more source

Large-scale proteomic analysis of T. spiralis muscle-stage ESPs identifies a novel upstream motif for in silico prediction of secreted products. [PDF]

open access: yesFront Parasitol, 2023
Nash B   +7 more
europepmc   +1 more source

Fase intestinal de trichinella spiralis en modelo murino [PDF]

open access: yes, 2009
RESUMEN Trichinella spiralis se encuentra principalmente en el hombre, rata, cerdo, perro; puede infectar a cualquier carnívoro u omnívoro. Cuando la carne o sus derivados están contaminados con larvas infectantes (LI) de T.
Moreno García, María Alejandra   +4 more
core  

Nachweise von Trichinella spiralis bei Hausschweinen

open access: yes, 2009
Nachweise von Trichinella spiralis bei Hausschweinen sowie von Trichinella spiralis / pseudospiralis bei Wildschweinen und Marderhunden 2005 - 2008 in Ostvorpommern2008 wurde in einer individuellen Tierhaltung im Landkreis Ostvorpommern (OVP) in ...
Kerlikowsky, H.   +4 more
core  

Trichinella spiralis, T-britovi, and T-nativa: infectivity, larval distribution in muscle, and antibody response after experimental infection of pigs

open access: yes, 1998
The infectivity of Trichinella spiralis, T. nativa, and T. britovi was experimentally compared in pigs. Blood sampling was performed weekly, and muscle juices were obtained at slaughter 10 weeks after inoculation.
Lind, Peter   +10 more
core   +1 more source

Trichinella spiralis excretory-secretory proteins induced autophagy via activating AMPK/mTOR pathway and protected gut epithelial barrier.

open access: yesPLoS Neglected Tropical Diseases
BackgroundTrichinella spiralis is an intestine- and tissue-dwelled parasitic nematode, the adult worms (AW) and muscle larvae parasitize in intracellular niche of intestinal epithelium and skeletal muscles of the same host, respectively.
Xin Zhuo Zhang   +8 more
doaj   +1 more source

Characterization of a novel pyruvate kinase from Trichinella spiralis and its participation in sugar metabolism, larval molting and development

open access: yesPLoS Neglected Tropical Diseases, 2022
Background Pyruvate kinase widely exists in many parasites and plays an important role in the energy production for the parasites. Pyruvate kinase might be a potential drug target for killing the parasites.
Wen Wen Yue   +8 more
doaj  

Virtual Screening Docking and ADMET Analysis of Small Molecules Targeting Thymidylate Synthase from Trichinella spiralis

open access: yes
<p>Trichinella spiralis (T. spiralis), a parasitic nematode responsible for human trichinellosis, poses<br>a significant global health threat.
Ummukulsu T S, Lakshminarayanan Karthik
core   +1 more source

Plancitoxin-1 mediates extracellular trap evasion by the parasitic helminth Trichinella spiralis

open access: yesBMC Biology
Background Trichinella spiralis (T. spiralis) is a parasitic helminth that causes a globally prevalent neglected zoonotic disease, and worms at different developmental stages (muscle larvae, adult worms, newborn larvae) induce immune attack at different ...
Jing Ding   +6 more
doaj   +1 more source

Uncommon and parallel developmental patterns of thymidylate synthase expression and localization in Trichinella spiralis and Caenorhabditis elegans

open access: yesPteridines, 2013
Trichinella spiralis is a parasitic nematode causing trichinellosis, a serious disease, and Caenorhabditis elegans is a free-living nematode, which is used as a model in parasitological studies. High levels of thymidylate synthase (EC 2.1.1.45; ThyA) and
Dąbrowska Magdalena   +7 more
doaj   +1 more source

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