Results 81 to 90 of about 1,773,732 (261)

First joint oscillation analysis of Super-Kamiokande atmospheric and T2K accelerator neutrino data [PDF]

open access: yes
International audienceThe Super-Kamiokande and T2K collaborations present a joint measurement of neutrino oscillation parameters from their atmospheric and beam neutrino data.
Tashiro, T   +999 more
core   +1 more source

Cerebral blood flow based on 3D-ASL technology in the early detection of mild cognitive impairment in type 2 diabetic patients: a pilot study

open access: yesFrontiers in Endocrinology
ContextType 2 diabetes mellitus (T2DM) significantly increases the risk of mild cognitive impairment (MCI), and earlier recognition is crucial for timely intervention and improving patients’ quality of life.ObjectiveThe aim of this study was to ...
Tingzhou Hou   +6 more
doaj   +1 more source

Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens

open access: yesFEBS Open Bio, EarlyView.
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee   +3 more
wiley   +1 more source

Search for light sterile neutrinos with the T2K far detector Super-Kamiokande at a baseline of 295 km [PDF]

open access: yes, 2019
International audienceWe perform a search for light sterile neutrinos using the data from the T2K far detector at a baseline of 295 km, with an exposure of 14.7(7.6)×1020 protons on target in neutrino (antineutrino) mode.
Morrison J.   +999 more
core   +1 more source

Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study and crowdsourcing opportunity

open access: yes, 2017
Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice.
G. P. Fadini   +19 more
core   +3 more sources

Refinement of Trend-to-Trend Cross-Calibration Total Uncertainties Utilizing Extended Pseudo Invariant Calibration Sites (EPICS) Global Temporally Stable Target

open access: yesRemote Sensing
Cross-calibration is an essential technique for calibrating Earth observation satellite sensors, which involves taking nearly simultaneous images of a ground target to compare an uncalibrated sensor to a well-calibrated reference sensor.
Minura Samaranayake   +3 more
doaj   +1 more source

From energy provision to protein synthesis: Tunnelling nanotubes as mediators of intercellular metabolic cooperation in cancer

open access: yesFEBS Open Bio, EarlyView.
The cytoskeleton‐mediated transport of mitochondria via tunnelling nanotubes restores respiration, increases ATP production, rescues cells from apoptosis, activates the AKT/mTOR signalling pathway, promotes cell migration and invasiveness, contributes to cancer progression and treatment resistance.
Stanislava Martínková, Jan Trnka
wiley   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

open access: yesFEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty   +13 more
wiley   +1 more source

Measurement of coherent $\pi^{+}$ production in low energy neutrino-Carbon scattering [PDF]

open access: yes, 2016
International audienceWe report the first measurement of the flux-averaged cross section for charged current coherent π+ production on carbon for neutrino energies less than 1.5 GeV to a restricted final state phase space region in the T2K near detector,
Poutissou J   +999 more
core   +1 more source

Is the Presence of a Depressive Disorder a Risk Factor for Worse Metabolic Outcomes Among Patients with Type 2 Diabetes Treated with GLP-1 Analogs?

open access: yesDiabetology
Background/Objectives: Type 2 diabetes mellitus (T2DM) is frequently associated with depressive disorder (DD), which negatively impacts glycemic control and overall metabolic outcomes.
Joana Nicolau   +6 more
doaj   +1 more source

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