ABSTRACT Glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) are widely used for managing Type 2 diabetes and obesity, with well‐documented and significant cardiometabolic benefits. Recent observational reports and pharmacovigilance data have raised concerns about a possible association between GLP‐1RAs‐particularly semaglutide‐ and non‐arteritic ...
Helen V. Danesh‐Meyer +1 more
wiley +1 more source
Fibre morphology, intramyocellular lipid content and 3D capillary architecture in human postural, respiratory and locomotor muscles in type 2 diabetes mellitus. [PDF]
Pollak N +11 more
europepmc +1 more source
Summary This study examined the change in weight at 6 months of naltrexone/bupropion (NB), a combination pharmacological therapy for weight management, in real‐world practice in Canada. The study was conducted through an observational, retrospective, single‐arm chart review of adult patients who attended the Wharton Medical Clinic in Ontario, Canada ...
Sean Wharton +4 more
wiley +1 more source
Dairy Intake and Type 2 Diabetes Mellitus in Iranian Older Adults: Insights From the Baseline Phase of the Birjand Longitudinal Aging Study. [PDF]
Darabi M +9 more
europepmc +1 more source
SCD2 Alleviates Diabetes‐Associated Cognitive Dysfunction by Improving Microglial Lipid Metabolism
This study reveals a novel mechanism of microglial metabolic dysfunction in diabetic cognitive impairment. Defective SCD2 disrupts monounsaturated fatty acid (MUFA) metabolism, triggering mitochondrial oxidative phosphorylation dysfunction and leading to abnormal lipid droplet accumulation (marked by PLIN2).
Yang Yang +5 more
wiley +1 more source
Application of diffusion tensor imaging analysis along perivascular spaces in evaluating glymphatic system function in type 2 diabetes mellitus. [PDF]
Wang Y +7 more
europepmc +1 more source
Testing the feasibility of an intermittent low‐energy diet in women with gestational diabetes
Abstract Aims The study aimed to assess feasibility, acceptability and safety of an ILED in a randomised controlled trial of ILED vs. best NHS care healthy diet and exercise advice in women with Gestational Diabetes Mellitus (GDM) with body mass index ≥27.5 kg/m2 (≥25 kg/m2 in high‐risk minority ethnic groups) in the last trimester of pregnancy ...
Elizabeth Dapre +11 more
wiley +1 more source
Modulatory role of blackberry fruit standardized extract on brain redox status and insulin signaling in type 2 diabetic rats. [PDF]
Ahmad I +10 more
europepmc +1 more source
Abstract Aims Fixed‐ratio combinations such as iGlarLixi are recommended over premixed insulin as first‐line injectable therapy for type 2 diabetes mellitus (T2DM), yet real‐world evidence on transitions from premix to iGlarLixi remains limited. This study aimed to evaluate the efficacy and safety of switching from premixed insulin to iGlarLixi in a ...
Chun‐Jui Huang +5 more
wiley +1 more source

