Results 221 to 230 of about 137,868 (314)

Inflammatory Cytokines Impair Glucagon Expression and Secretion in Pancreatic α‐Cells

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Insulin resistance and obesity‐associated inflammation are key drivers in the pathogenesis of Type 2 diabetes mellitus (T2DM). Whilst inflammatory cytokines are well known to impair β‐cell function, their impact on pancreatic α‐cells and glucagon (GCG) regulation remains poorly understood. In this study, we investigated the effects of the
Caroline Bickelmann   +5 more
wiley   +1 more source

Type 2 diabetes morbidity, mortality and its associated risk factors across Brazilian regions: findings from the Global Burden of Disease Study 2021. [PDF]

open access: yesArch Endocrinol Metab
Teixeira PP   +11 more
europepmc   +1 more source

Blood-pressure control and T2DM [PDF]

open access: yesNature Reviews Endocrinology, 2009
openaire   +1 more source

Investigating the Incremental Cost and Utilization Burden of Obstructive Sleep Apnea in Overweight to Severely Obese Patients

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims To quantify the incremental economic and utilization burden of comorbid obstructive sleep apnea (OSA) within an overweight to severely obese adult population. Material and Methods This retrospective cohort study utilized 2016–2025 IQVIA PharMetrics Plus Closed Health Plan commercial claims data to identify overweight to severely obese ...
Hyung Seok John Kim   +3 more
wiley   +1 more source

Multi‐Parametric Magnetic Resonance Imaging to Assess Empagliflozin Effect on the Kidneys in People With Type 2 Diabetes Mellitus: A Pilot Clinical Trial

open access: yesDiabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Empagliflozin is renoprotective in Type 2 diabetes mellitus (T2DM). Our primary aim was to assess empagliflozin's effect on glomerular filtration rate and renal vascular resistance using multiparametric MRI (MpMRI). Our secondary aim was to assess the impact of empagliflozin on additional MpMRI‐derived metrics including markers of tissue ...
Ruth P. Lim   +9 more
wiley   +1 more source

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