Results 121 to 130 of about 17,578 (215)

Image_1_Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa.tif

, 2019
The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-
Birgit Habenstein (530820), Charlotte Lombardi (446265), Luca Signor (461960), Jean-Marie Teulon (6526820), David Liebl (634602), Viviana Job (170783), Jean-Luc Pellequer (71225), Caroline Gebus (6526817), Eric Faudry (187704), Juliane Brock (457964), James Tolchard (4717461), Daphna Fenel (283080), Ina Attrée (4386568), Stephanie Bouillot (6526814), Antoine Loquet (232358), Andréa Dessen (55465)   +15 more
core   +1 more source

Image_2_Structural and Functional Characterization of the Type Three Secretion System (T3SS) Needle of Pseudomonas aeruginosa.tif

, 2019
The type three secretion system (T3SS) is a macromolecular protein nano-syringe used by different bacterial pathogens to inject effectors into host cells. The extracellular part of the syringe is a needle-like filament formed by the polymerization of a 9-
Birgit Habenstein (530820), Charlotte Lombardi (446265), Luca Signor (461960), Jean-Marie Teulon (6526820), David Liebl (634602), Viviana Job (170783), Jean-Luc Pellequer (71225), Caroline Gebus (6526817), Eric Faudry (187704), Juliane Brock (457964), James Tolchard (4717461), Daphna Fenel (283080), Ina Attrée (4386568), Stephanie Bouillot (6526814), Antoine Loquet (232358), Andréa Dessen (55465)   +15 more
core   +1 more source

T3SS-1 independent permissive cell model to decipher a new intracellular behavior of Salmonella.

, 2017
International audienceSalmonella Typhimurium remains a constant concern in breeding by its financial impact: loss of yield, animal death, persistence in farms. In human health, it remains the second most deadly foodborne infectious agent.
Wiedemann, Agnès, Burlaud Gaillard, Julien, Velge, Philippe, Trotereau, Jérôme, Sonia, Georgeault, Roche S.M., Sylvie, Le Vern, Yves, Virlogeux-Payant, Isabelle, Holbert, Sébastien   +8 more
core   +1 more source

Type III Secretion System in Intestinal Pathogens and Metabolic Diseases

Journal of Diabetes Research
Modern lifestyle changes, especially the consumption of a diet high in salt, sugar, and fat, have contributed to the increasing incidence and prevalence of chronic metabolic diseases such as diabetes, obesity, and gout.
Le Zhou, Yaoyuan Zhang, Shiqi Wu, Yiyu Kuang, Pengfei Jiang, Xiao Zhu, Kai Yin   +6 more
doaj   +1 more source

The human NAIP-NLRC4-inflammasome senses the Pseudomonas aeruginosa T3SS inner-rod protein

, 2017
International audienceWhile NLRC4-dependent sensing of intracellular Gram-negative pathogens such as Salmonella enterica serovar typhimurium is a beneficial host response, NLRC4-dependent sensing of the Pseudomonas aeruginosa type 3 secretion system ...
Guery, B., Kipnis, Eric, Teddy Grandjean, Eric Kipnis, Anne Boucher, Benoit Guery, Thepaut, M., Eric Faudry, Guery, Benoit, Boucher, Anne, Faudry, E., Laura Monlezun, Faudry, Eric, Thepaut, Marion, Dessein, Rodrigue, Rodrigue Dessein, Monlezun, Laura, Monlezun, L., Marion Thepaut, Dessein, R., Grandjean, Teddy, Grandjean, T., Boucher, A., Kipnis, E.   +23 more
core   +1 more source

DC3000 T3SS substrates and their scores after analysis by the TEREE algorithm.

, 2012
aExperimentally validated T3SS substrates that were not included in the positive training set are denoted by asterisks.
David J. Schneider (167932), Eric Sakk (167941), Alan Collmer (167937), Lisa M. Schechter (167923), Joy C. Valenta (167928)   +4 more
core   +1 more source

ssaN encodes for a protein with the conserved sequence of other T3SS ATPases.

, 2014
(A) Genetic organization of the T3SS-2 genes involved in S. Typhimurium virulence. Genes encoding for proteins for apparatus (yellow), effectors and translocators (red), chaperones (purple), and regulators (green) are shown. The ssaN gene is indicated by
Nobuhiko Okada (482513), Sayaka Ono (550020), Yukie Yoshida (550019), Tsuyoshi Miki (438827), Takeshi Haneda (550021), Masahiro Ito (134554)   +5 more
core   +1 more source

T3SS translocon induces pyroptosis by direct interaction with NLRC4/NAIP inflammasome

eLife
Abstract Type III secretion system (T3SS) is a virulence apparatus existing in many bacterial pathogens. Structurally, T3SS consists of the base, needle, tip, and translocon. The NLRC4 inflammasome is the major receptor for T3SS needle and basal rod proteins. Whether other T3SS components are recognized by NLRC4 is unclear.
Yan Zhao, Hanshuo Zhu, Jinqian Li, Hang Xu, Li Sun   +4 more
openaire   +3 more sources

Rooting the history of T3SS.

, 2012
(A) Representation of the three possible scenarios for the relative emergence of the flagellum and of the NF-T3SS. The numbers represent the percentage of each scenario in the bootstrap analysis of the ATPase family (out of 997 bootstrap trees where ...
Eduardo P. C. Rocha (7388), Sophie S. Abby (131993)   +1 more
core   +1 more source

Structural characterization and membrane localization of ExsB from the type III secretion system (T3SS) of Pseudomonas aeruginosa.

, 2011
International audiencePseudomonas aeruginosa is an opportunistic human pathogen that employs a finely tuned type III secretion system (T3SS) to inject toxins directly into the cytoplasm of target cells.
Caroline Perdu, Andréa Dessen, Job, Viviana, Ina Attree, Faudry, Eric, Thierry Izoré, Perdu, Caroline, Dessen, Andréa, Izoré, Thierry, Viviana Job, Attree, Ina, Eric Faudry   +11 more
core   +1 more source