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Population structure and phylogenetic analysis of Vibrio cholerae non-O1/O139 by whole genome sequencing. [PDF]

open access: yesPLoS One
Wells T   +6 more
europepmc   +1 more source
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Identification of chlamydial T3SS inhibitors through virtual screening against T3SS ATPase

Chemical Biology & Drug Design, 2017
Chlamydia trachomatis is a widespread sexually transmitted pathogen that resides within a special vacuole inside host cells. Although acute infection can be treated with antibiotics, chlamydia can enter persistent state, leading to chronic infection that is difficult to cure. Thus, novel anti‐chlamydial compounds active against persistent chlamydia are
Alexander V. Grishin   +6 more
openaire   +2 more sources

Host Cell Targeting by Enteropathogenic Bacteria T3SS Effectors

Trends in Microbiology, 2018
Microbial pathogens possess a diversity of weapons that disrupt host homeostasis and immune defenses, thus resulting in the establishment of infection. The best-characterized system mediating bacterial protein delivery into target eukaryotic cells is the type III secretion system (T3SS) expressed by Gram-negative bacteria, including the human enteric ...
Pinaud, Laurie   +2 more
openaire   +3 more sources

Polynucleotide Phosphorylase and the T3SS

2007
Low temperatures as well as encounters with host phagocytes are two stresses that have been relatively well studied in many species of bacteria. The exoribonuclease polynucleotide phosphorylase (PNPase) has previously been shown to be required by several species of bacteria, including Yersinia, for low-temperature growth. We have shown that PNPase also
Jason A, Rosenzweig, Kurt, Schesser
openaire   +2 more sources

Pore Formation by T3SS Translocators: Liposome Leakage Assay

2012
Gram-negative bacteria utilize a dedicated membrane-embedded apparatus, the type III secretion system (T3SS), to inject proteins into host cells. The passage of the proteins across the target membrane is accomplished by a proteinaceous pore-the translocon-formed within the host-cell cytoplasmic membrane.
Faudry, Eric   +2 more
openaire   +2 more sources

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