Results 181 to 190 of about 17,578 (215)

Spermidine targets GGA-rich small RNAs for virulence regulation. [PDF]

open access: yesiScience
Wang C   +7 more
europepmc   +1 more source

Regulation of T3SS Synthesis, Assembly and Secretion in Pseudomonas aeruginosa

open access: yesArchives of Microbiology, 2022
AbstractT3SS is an important virulence factor of Pseudomonas aeruginosa and has a central role in the infection process. However, the functional regulation of the T3SS by environmental signals is poorly understood. In our lab, we use fluorescence microscopy to study protein kinetics in real-time in live cells. In P.
H. M. Selim   +2 more
exaly   +3 more sources

The T3SS Effector Protease NleC Is Active Within Citrobacter rodentium [PDF]

open access: yesPathogens, 2021
Whether type III secretion system (T3SS) effector proteins encoded by Gram-negative bacterial pathogens have intra-bacterial activities is an important and emerging area of investigation. Gram-negative bacteria interact with their mammalian hosts by using secretion systems to inject virulence proteins directly into infected host cells.
Philip R Hardwidge   +2 more
exaly   +4 more sources

The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape [PDF]

open access: yesMicroorganisms, 2020
Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are Escherichia coli pathovars that are characterized by the harboring of a large plasmid that encodes most virulence genes, including a type III secretion system (T3SS).
Francois-xavier Campbell-valois   +2 more
exaly   +4 more sources

Identification of chlamydial T3SS inhibitors through virtual screening against T3SS ATPase

Chemical Biology & Drug Design, 2017
Chlamydia trachomatis is a widespread sexually transmitted pathogen that resides within a special vacuole inside host cells. Although acute infection can be treated with antibiotics, chlamydia can enter persistent state, leading to chronic infection that is difficult to cure. Thus, novel anti‐chlamydial compounds active against persistent chlamydia are
Alexander V. Grishin   +6 more
openaire   +2 more sources

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