Enzymatic versatility of the salmonella effector SopB enables manipulation of host phosphoinositide signalling. [PDF]
Jensen RC, Fairn GD.
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Lithocholic acid induces T3SS-dependent formation of invasion-competent <i>Shigella flexneri</i> aggregates. [PDF]
Lanier J +3 more
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Spermidine targets GGA-rich small RNAs for virulence regulation. [PDF]
Wang C +7 more
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Genomic insights into <i>Aeromonas</i> infections in diarrheal patients: high diversity, emerging resistance, and potential outbreak in Beijing. [PDF]
Yan A +9 more
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Regulation of T3SS Synthesis, Assembly and Secretion in Pseudomonas aeruginosa
AbstractT3SS is an important virulence factor of Pseudomonas aeruginosa and has a central role in the infection process. However, the functional regulation of the T3SS by environmental signals is poorly understood. In our lab, we use fluorescence microscopy to study protein kinetics in real-time in live cells. In P.
H. M. Selim +2 more
exaly +3 more sources
The T3SS Effector Protease NleC Is Active Within Citrobacter rodentium [PDF]
Whether type III secretion system (T3SS) effector proteins encoded by Gram-negative bacterial pathogens have intra-bacterial activities is an important and emerging area of investigation. Gram-negative bacteria interact with their mammalian hosts by using secretion systems to inject virulence proteins directly into infected host cells.
Philip R Hardwidge +2 more
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The T3SS of Shigella: Expression, Structure, Function, and Role in Vacuole Escape [PDF]
Shigella spp. are one of the leading causes of infectious diarrheal diseases. They are Escherichia coli pathovars that are characterized by the harboring of a large plasmid that encodes most virulence genes, including a type III secretion system (T3SS).
Francois-xavier Campbell-valois +2 more
exaly +4 more sources
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Identification of chlamydial T3SS inhibitors through virtual screening against T3SS ATPase
Chemical Biology & Drug Design, 2017Chlamydia trachomatis is a widespread sexually transmitted pathogen that resides within a special vacuole inside host cells. Although acute infection can be treated with antibiotics, chlamydia can enter persistent state, leading to chronic infection that is difficult to cure. Thus, novel anti‐chlamydial compounds active against persistent chlamydia are
Alexander V. Grishin +6 more
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