Results 151 to 160 of about 8,261,953 (362)

CORELATIONS BETWEEN THE CLINICAL AND MORFOLOGICAL ASPECTS AND THE MOLECULAR MARKERS IN THE MALIGNANT TRANSFORMATION OF THE ORAL LEUKOPLAKIAS

Romanian Journal of Oral Rehabilitation, 2016
The leukoplakia injuries represent the most frequent premalignant oral injuries. Their clinical and histopathological features are not always significant for the malignant transformation and, implicitly, for their diagnosis.
Doinița Olinici, Laura Gheucă-Solovăstru, Tatiana Țăranu, L. Bădescu, Laura Stoica, Emanuela Ana Botez, Carmen Elena Cotrutz   +6 more
doaj  

The Poisson Rain Tessellation Under Spatial Expansion and Temporal Transformation [PDF]

arXiv, 2012
For cell-division processes in a window, Cowan introduced four selection rules and two division rules each of which stands for one cell-division model. One of these is the area-weighted in-cell model. In this model, each cell is selected for division with a probability that corresponds to the ratio between its area and the area of the whole window ...
arxiv  

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Proliferation-driven mechanical feedback regulates cell dynamics in growing tissues [PDF]

arXiv
Local stresses in a tissue, a collective property, regulate cell division and apoptosis. In turn, cell growth and division induce active stresses in the tissue. As a consequence, there is a feedback between cell growth and local stresses. However, how the cell dynamics depend on local stress-dependent cell division and the feedback strength is not ...
arxiv  

The thioredoxin‐like and one glutaredoxin domain are required to rescue the iron‐starvation phenotype of HeLa GLRX3 knock out cells

FEBS Letters, EarlyView.
Glutaredoxin (Grx) 3 proteins contain a thioredoxin domain and one to three class II Grx domains. These proteins play a crucial role in iron homeostasis in eukaryotic cells. In human Grx3, at least one of the two Grx domains, together with the thioredoxin domain, is essential for its function in iron metabolism.
Laura Magdalena Jordt, Manuela Gellert, Finja Zelms, Sander Bekeschus, Christopher Horst Lillig   +4 more
wiley   +1 more source

Dose Effects of Recombinant Adenovirus Immunization in Rodents

Vaccines, 2019
Recombinant adenovirus type 5 (rAd) has been used as a vaccine platform against many infectious diseases and has been shown to be an effective vaccine vector.
Eric A. Weaver
doaj   +1 more source

VIRUS-SPECIFIC NUCLEIC ACIDS IN SV40-EXPOSED HAMSTER EMBRYO CELL LINES: CORRELATION WITH S AND T ANTIGENS [PDF]

, 1969
Myron J. Levin, Michael N. Oxman, George Th. Diamandopoulos, Arthur S. Levine, Patrick H. Henry, John F. Enders   +5 more
openalex   +1 more source

In vivo evidence for glycyl radical insertion into a catalytically inactive variant of pyruvate formate‐lyase

FEBS Letters, EarlyView.
Dimeric pyruvate formate‐lyase cleaves pyruvate using a radical‐based mechanism. G734 serves as a radical storage location, and the radical is transferred to the catalytic C419 residue. Mutation of the C418‐C419 pair causes loss of enzyme activity, but does not impede radical introduction onto G734. Therefore, cis‐ but not trans‐radical transfer occurs
Michelle Kammel, A. F. Volker Wagner, R. Gary Sawers   +2 more
wiley   +1 more source

Flow‐based immunomagnetic enrichment of circulating tumor cells from diagnostic leukapheresis product

Molecular Oncology, EarlyView.
The number of circulating tumor cells obtained from prostate cancer patients was increased approximately 5‐fold compared to regular CellSearch when processing 2 mL diagnostic leukapheresis material aliquots and increased by 44‐fold when processing 20 mL DLA aliquots using the flow enrichment target capture Halbach‐array.
Michiel Stevens, Anouk Mentink, Frank A. W. Coumans, Eshwari Dathathri, Khrystany T. Isebia, Jaco Kraan, Ronald de Wit, John W. M. Martens, Leon W. M. M. Terstappen   +8 more
wiley   +1 more source

Illuminating T cell-dendritic cell interactions in vivo by FlAsHing antigens

eLife
Delineating the complex network of interactions between antigen-specific T cells and antigen presenting cells (APCs) is crucial for effective precision therapies against cancer, chronic infections, and autoimmunity.
Munir Akkaya, Jafar Al Souz, Daniel Williams, Rahul Kamdar, Olena Kamenyeva, Juraj Kabat, Ethan Shevach, Billur Akkaya   +7 more
doaj   +1 more source