Results 261 to 270 of about 4,652,143 (319)

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Protein-dependent CD4⁺ T cell specialization and CD8⁺ T cell-driven IL-2 production in HIV. [PDF]

iScience
Pušnik J, Heinemann FM, Heinold A, Richter E, Esser S, Streeck H.   +5 more
europepmc   +1 more source

Alternatively activated neutrophils limit T cell-driven neuroinflammation. [PDF]

J Neuroinflammation
Atkinson JR, Bellinger C, Jerome AD, Gardner AM, Groover HK, Chen S, Moffatt AM, Sepeda JA, Dokiburra A, Hammond LA, Liu T, Webb A, Sas AR, Segal BM.   +13 more
europepmc   +1 more source

CAR-T cell immunotherapy in rhabdomyosarcoma. [PDF]

J Transl Med
Safarzadeh Kozani P, Dashti Shokoohi S, Safarzadeh Kozani P.   +2 more
europepmc   +1 more source

Mechanistic basis and therapeutic modulation of T cell fitness to enhance CAR-T cell efficacy in hematological malignancies. [PDF]

Front Immunol
Makni-Maalej K, Alotaibi SM, Fernandes Q, Ahmed SO, Mestiri S, Bougarn S, Amir W, Farhatullah S, Kharfan-Dabaja M, Merhi M, Fakih RE, Aljurf M, Dermime S.   +12 more
europepmc   +1 more source

Enable CAR T cell immunotherapy in glioblastoma by modifying its microenvironment via oncolytic adenovirus encoding bispecific T cell engager. [PDF]

Mol Ther Oncol
Choi MJ, So EY, Akosman B, Lee YE, Raufi AG, Reginato AM, Chen CC, Lawler SE, Wong ET, Liang OD.   +9 more
europepmc   +1 more source