Results 201 to 210 of about 14,398,598 (290)

A cell line development vector strategy for improved expression of a trispecific T-cell engager in CHO. [PDF]

MAbs
Mistry RK, Nui C, Lambiase G, Ray D, Kearsey L, Hitchcock N, Grassi L, Elgendy R, Fleming J, Broughton AC, Zhao P, Chiang CI, Shah P, Cyr M, Walseng E, Mazor Y, Hatton D, Dunn S.   +17 more
europepmc   +1 more source

Protein‐Nanoarchitectures for Low‐Field Intracellular Electro‐Immunomodulation

Advanced Functional Materials, EarlyView.
DHQ‐SDH‐mediated binding of AuNPs drives the formation of interconnected, chain‐like nanoarchitectures with enhanced electrical conductivity. These conductive assemblies undergo macrophage uptake and enable low‐field electrical stimulation, promoting M1‐to‐M2 phenotypic switching with decreased iNOS and increased CD206 expression. Such protein‐mediated
Viktoriya Pakharenko, Djanira Rodrigues Negrão, Tanmay Gupta, Robert Jeng, Otavio Augusto Titton Dias, Maia Jaffer‐Diaz, Dinesh Christendat, Mohini Sain   +7 more
wiley   +1 more source

Author Correction: MAGE-A4/MAGE-A8-targeted TCR-based bispecific T cell engager in recurrent and/or refractory solid tumors: a phase 1 trial. [PDF]

Nat Med
Wermke M, Ochsenreither S, Jaeger D, Becker H, Bleckmann A, Bozorgmehr F, Chatterjee M, Groepper S, Haenel M, Hecker JS, Häring MF, Heudobler D, Hilf N, Hofmann M, Hutt M, Mayer-Mokler A, Missel S, Ruh M, Schuster H, Veremchuk O, Kleemiss M, Knop S, Laban S, Sebastian M, Spoerl S, Britten CM, Reinhardt C.   +26 more
europepmc   +1 more source

Sacrificial‐Layer‐Assisted Heat‐Affected‐Zone Suppression in Laser Patterning of PET for High‐Performance Flexible Devices

Advanced Functional Materials, EarlyView.
A removable sacrificial polymer layer engineers the thermal boundary condition during nanosecond laser ablation of PET, suppressing heat‐affected‐zone formation without relying on costly ultrafast lasers. This strategy enables deep, high‐aspect‐ratio trenches with no detectable heat‐affected zone, templating silver‐filled mesh electrodes with record ...
Mehdi Zarei, Mirza Sahaluddin, Mostafa Bedewy, Paul W. Leu   +3 more
wiley   +1 more source

Fully human anti-FOLR1 T-cell engager demonstrates potent activity in CBFA2T3::GLIS2 acute megakaryoblastic leukemia. [PDF]

Blood Neoplasia
Morris SM, Pilat K, Girard EJ, Noll A, Ang LS, Price J, Mhyre AJ, Correnti CE, Bandaranayake AD, Mehlin C, Clarke M, Brasel K, Muthuraman P, Crook ZR, Cole B, Hylkema TA, Le Q, Meshinchi S, Olson JM.   +18 more
europepmc   +1 more source

Nano Borophene as a Programmable 2D Scaffold for Organized DNA Assembly and Long‐Range Energy Transfer

Advanced Functional Materials, EarlyView.
Borophene is introduced as a programmable 2D bio‐interface that organizes DNA through dual boron–sulfur and nucleobase interactions. This molecular architecture enables efficient long‐range nanosurface energy transfer, establishing new design principles for functional nano–bio interfaces and amplification‐free optical biosensing.
Teresa Aditya, Pranay Saha, John M. Sansalone, Shraddha Krishnakumar, Matthew Molinaro, André J. van der Vlies, Nada Maher, Adrienne Griffiths, Zakhro Zakirova, Ketan Dighe, Narayana R. Aluru, Dipanjan Pan   +11 more
wiley   +1 more source

Erratum: A KRAS^G12V-targeted bispecific T cell engager promotes immunity against colorectal solid tumor. [PDF]

Mol Ther Oncol
Huynh N, Thi Nguyen TM, Bui NT, Nguyen HN, Nguyen CT.   +4 more
europepmc   +1 more source

Full‐Field Damage Monitoring in Architected Lattices Using In situ Electrical Impedance Tomography

Advanced Functional Materials, EarlyView.
In situ electrical impedance tomography (EIT) turns 3D‐printed, CNT‐infused architected lattices into full‐field damage‐imaging systems. Tunable Voronoi‐based geometries act as active sensing architectures, enabling conductivity maps to detect early‐stage damage and localise sequential ligament fracture before catastrophic failure.
Akash Deep, Andrea Samore, Alistair McEwan, Andrew McBride, Shanmugam Kumar   +4 more
wiley   +1 more source

A phase 1 study of PF-07260437, a B7-H4 × CD3 bispecific T-cell engager, in patients with advanced or metastatic breast, ovarian, and endometrial cancer. [PDF]

Invest New Drugs
Yan F, Cruz-Correa M, Specht J, Wang EW, Lu J, Soliman H, Jackson-Fisher A, Tang SY, Jiang S, Le Corre C, Li M, Sommerhalder D.   +11 more
europepmc   +1 more source

Mechanics of Telson Ridges in Mantis Shrimp for Impact Analysis and Implications for Bioinspired Elastic Shell Designs

Advanced Functional Materials, EarlyView.
The mantis shrimp telson reveals how ridged biological shields control deformation under impact. Inspired by this architecture, telson‐inspired ridged curved shells transform ridge geometry and macroscopic curvature into bidirectional snap‐through, tunable stiffness, and enhanced hysteretic energy dissipation for multifunctional architected materials ...
Phani Saketh Dasika, Adwait Trikanad, Wei Huang, Taige Hao, David Kisailus, Pablo D. Zavattieri   +5 more
wiley   +1 more source