Results 181 to 190 of about 1,632,256 (263)

Predicting the conformational flexibility of antibody and T cell receptor complementarity-determining regions. [PDF]

Nat Mach Intell
Spoendlin FC, Fernández-Quintero ML, Raghavan SSR, Turner HL, Gharpure A, Loeffler JR, Wong WK, Bujotzek A, Georges G, Ward AB, Deane CM.   +10 more
europepmc   +1 more source

Involvement of Prep1 in the αβ T-Cell Receptor T-Lymphocytic Potential of Hematopoietic Precursors

, 2005
Dmitri Penkov, Patrizia Rosa, Luis C. Fernández, Veronica Basso, Elisabetta Ferretti, Fabio Grassi, Anna Mondino, Francesco Blasi   +7 more
openalex   +1 more source

Detection of circulating tumor DNA in colorectal cancer patients using a methylation‐specific droplet digital PCR multiplex

Molecular Oncology, EarlyView.
We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto, Louise Raunkilde, Jan Lindebjerg, Mads Malik Aagaard, Christina Therkildsen, Jakob Kleif, Lars Henrik Jensen, Torben Frøstrup Hansen, Rikke Fredslund Andersen   +8 more
wiley   +1 more source

Distinct characteristics of T cell receptor repertoire associated with the SARS-CoV-2 reinfection. [PDF]

Front Immunol
Zeng L, Liu L, Ren B, Feng B, Lai X, Lai X, Chen Z, Huang Y, Hong W.   +8 more
europepmc   +1 more source

Mineralocorticoid receptor signaling reduces numbers of circulating human naïve T cells and increases their CD62L, CCR7, and CXCR4 expression [PDF]

, 2014
Luciana Besedovsky, Barbara Linz, Jan Born, Tanja Lange   +3 more
openalex   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Conditional generation of real antigen-specific T cell receptor sequences. [PDF]

Nat Mach Intell
Karthikeyan D, Bennett SN, Reynolds AG, Vincent BG, Rubinsteyn A.   +4 more
europepmc   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

Molecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj, Clara Frick, Ben Schöttker, Bernd Holleczek, Hermann Brenner   +4 more
wiley   +1 more source

SatTCR: a pipeline for performing saturation analysis of the T cell receptor repertoire and a case study of a healthy canine. [PDF]

MethodsX
Welch Schwartz R, Zuleger CL, Newton MA, Vail DM, Albertini MR, Ong IM.   +5 more
europepmc   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source