Results 321 to 330 of about 27,916,234 (409)

An intra-tumoral niche maintains and differentiates stem-like CD8 T cells

Nature, 2019
Caroline S. Jansen, Nataliya Prokhnevska, V. Master, M. Sanda, J. Carlisle, M. Bilen, M. Cardenas, S. Wilkinson, Ross Lake, A. Sowalsky, R. Valanparambil, W. Hudson, D. McGuire, K. Melnick, A. I. Khan, K. Kim, Y. Chang, Alice Kim, C. Filson, M. Alemozaffar, A. Osunkoya, Patrick Mullane, C. Ellis, Rama S. Akondy, S. Im, A. Kamphorst, A. Reyes, Yuan Liu, H. Kissick   +28 more
semanticscholar   +1 more source

Advances and challenges in identifying precursors of memory CD4⁺ T cells. [PDF]

Front Immunol
Liu J, Song W, Tang H.
europepmc   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Circulating IL6 is involved in the infiltration of M2 macrophages and CD8+ T cells. [PDF]

Sci Rep
Huang J, Xiao R, Shi S, Li Q, Li M, Xiao M, Wang Y, Yang Y, Li W, Tang Y.   +9 more
europepmc   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

The ammonia-Slc4a11 axis in T cells alleviates LPS-induced mastitis. [PDF]

Front Immunol
Wu Y, Li Z, Xi P, Wang Y, Guo H, Yin H, Zhu L.   +6 more
europepmc   +1 more source

Cell to cell transfer of RNA into transformed cells [PDF]

Journal of Cellular Physiology, 1972
openaire   +3 more sources

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Chimeric antigen receptor T cells persist and induce sustained remissions in relapsed refractory chronic lymphocytic leukemia

Science Translational Medicine, 2015
D. Porter, W. Hwang, N. Frey, S. Lacey, P. Shaw, A. Loren, A. Bagg, K. Marcucci, A. Shen, V. Gonzalez, David E. Ambrose, S. Grupp, A. Chew, Zhaohui Zheng, M. Milone, B. Levine, J. Melenhorst, C. June   +17 more
semanticscholar   +1 more source