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Cell-to-Cell Heterogeneity in Trypanosomes
Annual Review of Microbiology, 2021Recent developments in single-cell and single-molecule techniques have revealed surprising levels of heterogeneity among isogenic cells. These advances have transformed the study of cell-to-cell heterogeneity into a major area of biomedical research, revealing that it can confer essential advantages, such as priming populations of unicellular organisms
Luzak, Vanessa +3 more
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Pan-cancer single-cell landscape of tumor-infiltrating T cells
Science, 2021Description An atlas of cancer-associated T cells The tumor microenvironment contains many different kinds of immune cells, the composition, function, and roles of which are unclear.
Liangtao Zheng +18 more
semanticscholar +1 more source
The Myeloid Cell Compartment—Cell by Cell
Annual Review of Immunology, 2019Myeloid cells are a major cellular compartment of the immune system comprising monocytes, dendritic cells, tissue macrophages, and granulocytes. Models of cellular ontogeny, activation, differentiation, and tissue-specific functions of myeloid cells have been revisited during the last years with surprising results; for example, most tissue macrophages ...
Joachim L. Schultze +6 more
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Nursing Standard, 2012
This article, which forms part of the life sciences series, aims to promote understanding of the basic structure and function of cells. It assists healthcare professionals to appreciate the complex anatomy and physiology underpinning the functioning of the human body. Several introductory chemical concepts and terms are outlined.
Farley, Alistair +2 more
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This article, which forms part of the life sciences series, aims to promote understanding of the basic structure and function of cells. It assists healthcare professionals to appreciate the complex anatomy and physiology underpinning the functioning of the human body. Several introductory chemical concepts and terms are outlined.
Farley, Alistair +2 more
openaire +3 more sources
VIRUS-CELL AND CELL-CELL FUSION
Annual Review of Cell and Developmental Biology, 1996▪ Abstract Significant progress has been made in elucidating the mechanisms of viral membrane fusion proteins; both those that function at low, as well as those that function at neutral, pH. For many viral fusion proteins evidence now suggests that a triggered conformational change that exposes a previously cryptic fusion peptide, along with a ...
Tyra G. Wolfsberg +3 more
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The cell biology of cell-in-cell structures
Nature Reviews Molecular Cell Biology, 2008For decades, authors have described unusual cell structures, referred to as cell-in-cell structures, in which whole cells are found in the cytoplasm of other cells. One well-characterized process that results in the transient appearance of such structures is the engulfment of apoptotic cells by phagocytosis.
Michael Overholtzer, Joan S. Brugge
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Cell-to-cell communication in cultured Sertoli cells
Pfl�gers Archiv European Journal of Physiology, 1985Junctional transfer of ions in monolayer primary cultures of Sertoli cells has been studied by using conventional techniques. Cells were extensively electrically coupled. Membrane voltage displacements caused by the injected current pulses were measured at variable interelectrode distance. Data analyses were based on a thin-sheet model for current flow
Fabrizio Eusebi +5 more
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CELL INJURY AND CELL DEATH [PDF]
, 2011 WHEN CELLS are damaged, as often occurs during trauma and metabolic stress, the organism has to choose whether to repair the damage by promoting cell survival or remove irreparably injured cells. Cell injury occurs when an adverse stimulus reversibly disrupts the normal, complex homeostatic balance of the cellular metabolism. In this case, after injury
BARONI, Adone +3 more
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Regulatory T Cells and Human Disease.
Annual Review of Immunology, 2020Naturally occurring CD4+ regulatory T (Treg) cells, which specifically express the transcription factor FoxP3 in the nucleus and CD25 and CTLA-4 on the cell surface, are a functionally distinct T cell subpopulation actively engaged in the maintenance of ...
S. Sakaguchi +5 more
semanticscholar +1 more source
2011
Gene therapy based on the use of viral vectors is entirely dependent on the use of animal cell lines, mainly of mammalian origin, but also of insect origin. As for any biotechnology product for clinical use, viral -vectors have to be produced with cells derived from an extensively characterized cell bank to maintain the appropriate standard for ...
Stacey, G. N., Merten, O. W.
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Gene therapy based on the use of viral vectors is entirely dependent on the use of animal cell lines, mainly of mammalian origin, but also of insect origin. As for any biotechnology product for clinical use, viral -vectors have to be produced with cells derived from an extensively characterized cell bank to maintain the appropriate standard for ...
Stacey, G. N., Merten, O. W.
openaire +7 more sources