Results 141 to 150 of about 469,115 (308)

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

open access: yesMolecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain   +10 more
wiley   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

open access: yesMolecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner   +14 more
wiley   +1 more source

The Construction of Minimal (b,t)-Blocking Sets Containing Conics in PG(2,5) with the Complete Arcs and Projective Codes Related with Them

open access: yesIbn Al-Haitham Journal for Pure and Applied Sciences, 2017
A (b,t)-blocking set B in PG(2,q) is set of b points such that every line of PG(2,q) intersects B in at least t points and there is a line intersecting B in exactly t points.
Amal Shihab Al-Mukhtar   +1 more
doaj  

Systematic redundant residue number system codes: analytical upper bound and iterative decoding performance over AWGN and Rayleigh channels

open access: yes, 2006
The novel family of redundant residue number system (RRNS) codes is studied. RRNS codes constitute maximum–minimum distance block codes, exhibiting identical distance properties to Reed–Solomon codes.
Liew, T.H., Yang, L-L., Hanzo, L.
core  

A Decoding Algorithm for LDPC Codes Over Erasure Channels with Sporadic Errors

open access: yes, 2010
An efficient decoding algorithm for low-density parity-check (LDPC) codes on erasure channels with sporadic errors (i.e., binary error-and-erasure channels with error probability much smaller than the erasure probability) is proposed and its performance ...
Paolini, Enrico   +9 more
core   +1 more source

Adaptor protein CIN85 potentiates the motility of osteosarcoma cells via the Akt/mTOR and MMP2‐COL3A1 axis

open access: yesMolecular Oncology, EarlyView.
CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak   +10 more
wiley   +1 more source

Enhancing the shopping experience through QR codes: the perspective of the Romanian users

open access: yesAmfiteatru Economic, 2015
The progress registered in the field of information and communication technologies has induced significant changes in the purchasing behaviour of the consumers who nowadays want simultaneous use of online and offline channels within the same shopping ...
Irina Albăstroiu , Mihai Felea
doaj  

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

RS + LDPC-Staircase Codes for the Erasure Channel: Standards, Usage and Performance [PDF]

open access: yes, 2013
Application-Level Forward Erasure Correction (AL-FEC) codes are a key element of telecommunication systems. They are used to recover from packet losses when retransmission are not feasible and to optimize the large scale distribution of contents. In this
Detchart, Jonathan   +4 more
core  

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Home - About - Disclaimer - Privacy