Results 131 to 140 of about 469,115 (308)

Concatenated Turbo/LDPC codes for deep space communications: performance and implementation [PDF]

, 2013
Deep space communications require error correction codes able to reach extremely low bit-error-rates, possibly with a steep waterfall region and without error floor. Several schemes have been proposed in the literature to achieve these goals.
Condo, Carlo
core  

Somatic mutational landscape in von Hippel–Lindau familial hemangioblastoma

Molecular Oncology, EarlyView.
The causes of central nervous system (CNS) hemangioblastoma in Von Hippel–Lindau (vHL) disease are unclear. We used Whole Exome Sequencing (WES) on familial hemangioblastoma to investigate events that underlie tumor development. Our findings suggest that VHL loss creates a permissive environment for tumor formation, while additional alterations ...
Maja Dembic, Anne Nørremølle, Lilian Bomme Ousager, Lars van Brakel Andersen, Marie Louise Mølgaard Binderup, Mads Thomassen   +5 more
wiley   +1 more source

Experimental Study on Shear Failure of 30 m Pre-Tensioned Concrete T-Beams Under Small Shear Span Ratio

Buildings
Pre-tensioned concrete T-beams with draped strands have been gradually promoted and used in bridge construction in recent years due to their advantages such as simple structure, efficient force distribution, and few defects.
Qianyi Zhang, Hai Yan, Chunlei Zhang, Ding-Hao Yu, Jiaolei Zhang, Gang Li, Mingguang Wei, Jinglin Tao, Huiteng Pei   +8 more
doaj   +1 more source

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Shear Strength of RC T-Beams Without Shear Reinforcement Based on Crack Sliding Model

Buildings
Considering the effect of the flange on the shear capacity of reinforced concrete (RC) beams without stirrups, a shear capacity calculation formula based on the crack sliding model is proposed for RC beams without stirrups in this paper. Test data of 444
Penggang Tian, Yufei Han, Kai Wang, Jiajia Wang, Zhiheng Tian, Ergang Xiong   +5 more
doaj   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Iterative Soft-Decision Decoding of Binary Cyclic Codes

Journal of Communications Software and Systems, 2008
Binary cyclic codes achieve good error correction performance and allow the implementation of very simpleencoder and decoder circuits. Among them, BCH codesrepresent a very important class of t-error correcting codes, with known structural properties and
Marco Baldi, Giovanni Cancellieri, Franco Chiaraluce   +2 more
doaj  

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Constructing DNA Codes with Larger Distance from Quaternary Words

Jambura Journal of Mathematics
In this work, we propose a novel method to construct DNA codes from quaternary words. The method uses permutation groups that act in the set {1, 2, …, 4n}, representing the coordinate and coordinate value of quaternary words.
Benediktus Panji Pradipta, Nikken Prima Puspita   +1 more
doaj   +1 more source