Results 11 to 20 of about 12,899,769 (365)
Functional exhaustion of antiviral lymphocytes in COVID-19 patients
In December 2019, a novel coronavirus was first reported in Wuhan, China. It was named by the World Health Organization as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and is responsible for coronavirus disease 2019 (COVID-19).
M. Zheng +7 more
semanticscholar +1 more source
Reprogrammed CD8+ T-Lymphocytes Isolated from Bone Marrow Have Anticancer Potential in Lung Cancer
CD8+ T-lymphocytes play a key role in antitumor immune response. Patients with lung cancer often suffer from T-lymphocyte dysfunction and low T-cell counts. The exhaustion of effector T-lymphocytes largely limits the effectiveness of therapy.
Evgenii G. Skurikhin +12 more
doaj +1 more source
Lymphocytes in atherosclerosis [PDF]
It is well established that atherosclerosis is caused by an inflammatory process in the arterial intima. However, it is only in recent years that it has become clear that this inflammation is modulated by immune responses against plaque antigens. These antigens are primarily believed to be modified self-antigens such as oxidized LDL.
Wigren, Maria +2 more
openaire +5 more sources
NFAT2 regulates generation of innate-like CD8+ T lymphocytes and CD8+ T lymphocytes responses
NFAT2 null mutant mice die in utero of cardiac failure, precluding analysis of the role of NFAT2 in lymphocyte responses. Only the NFAT2-/-/Rag-1-/- chimeric mice model gave insight into the role of NFAT2 transcription factor in T lymphocyte development,
Emilia Pachulec +2 more
doaj +1 more source
Organic basis of gastrointestinal symptoms is in the scope of many specialists. In this article lymphocytic gastritis, relatively newly described and not widely-known entity is presented. The lesion is characterized by presence of numerous mature lymphocytes in the surface and foveolar epithelium, as well as lymphocytic infiltration of the lamina ...
Michał Puderecki +3 more
openaire +4 more sources
"Proliferation of cytotoxic and activated T cells during acute Epstein-Barr virus induced Infectious Mononucleosis " [PDF]
The immune responses that develop following Epstien-Barr Virus (EBV) infection are complex and involve both humoral and to a greater extent cell-mediated immune mechanisms. To evaluate the immune response, flow cytometric analysis of the peripheral blood
Mansoori SD +1 more
doaj +1 more source
Capturing T Lymphocytes’ Dynamic Interactions With Human Neural Cells Using Time-Lapse Microscopy
To fully perform their functions, T lymphocytes migrate within organs’ parenchyma and interact with local cells. Infiltration of T lymphocytes within the central nervous system (CNS) is associated with numerous neurodegenerative disorders.
Florent Lemaître +13 more
doaj +1 more source
Near-infrared imaging of adoptive immune cell therapy in breast cancer model using cell membrane labeling. [PDF]
The overall objective of this study is to non-invasively image and assess tumor targeting and retention of directly labeled T-lymphocytes following their adoptive transfer in mice.
Fatma M Youniss +8 more
doaj +1 more source
Activated microglia and infiltrating lymphocytes are neuropathological hallmarks of amyotrophic lateral sclerosis (ALS), a fatal motoneuron disease.
Weihua Zhao +4 more
doaj +1 more source
Significance None of the single-cell RNA sequencing (scRNA-seq) studies published so far convincingly identified human γδ T lymphocytes despite their anticancer functions.
Gabriele Pizzolato +18 more
semanticscholar +1 more source

