Results 281 to 290 of about 1,267,388 (382)

Differential regulation of calcium-NFAT signaling pathway by Akt isoforms: unraveling effector dynamics and exhaustion of cytotoxic T lymphocytes in tumor microenvironment. [PDF]

J Immunother Cancer
Chen WL, Chang YL, Lin SF, Protzer U, Isogawa M, Yang HC, Huang LR.   +6 more
europepmc   +1 more source

A Porphyrin Nanomaterial for Photoimmunotherapy for Treatment of Melanoma

Advanced Science, EarlyView.
The TPC@OVA NPs are developed as dual‐functional nanomaterials combining phototherapy and immunotherapy for melanoma treatment. This system effectively ablates primary tumors, induces immunogenic cell death, promotes dendritic cell maturation, and enhances T cell activation.
Zhuang Fan, Qing Pei, Haojie Sun, Haiyan Zhang, Zhigang Xie, Tao Zhang, Chong Ma   +6 more
wiley   +1 more source

A pooled CRISPR screen identifies the Tα2 enhancer element as a driver of <i>TRA</i> expression in a subset of mature human T lymphocytes. [PDF]

Front Immunol
Schönberg PY, Muñoz-Ovalle Á, Paszkowski-Rogacz M, Crespo E, Sürün D, Feldmann A, Buchholz F.   +6 more
europepmc   +1 more source

Engineering the Immune Response to Biomaterials

Advanced Science, EarlyView.
This paper reviews immune responses to biomaterials, stages of evolution in relation to managing these responses ranging from preventing to modulating them. It also discusses state‐of‐the‐art strategies to modulate these responses and modes of their delivery.
Abolfazl Salehi Moghaddam, Mehran Bahrami, Einollah Sarikhani, Rumeysa Tutar, Yavuz Nuri Ertas, Faleh Tamimi, Ali Hedayatnia, Clotilde Jugie, Houman Savoji, Asma Talib Qureshi, Muhammad Rizwan, Chima V. Maduka, Nureddin Ashammakhi   +12 more
wiley   +1 more source

Alternative splicing of modulatory immune receptors in T lymphocytes: a newly identified and targetable mechanism for anticancer immunotherapy. [PDF]

Front Immunol
Tzaban S, Stern O, Zisman E, Eisenberg G, Klein S, Frankenburg S, Lotem M.   +6 more
europepmc   +1 more source

Cell Interactions Between Histoincompatible T and B Lymphocytes. The H-2 Gene Complex Determines Successful Physiologic Lymphocyte Interactions

, 1973
David H. Katz, Toshiyuki Hamaoka, Martin E. Dorf, Baruj Benacerraf   +3 more
openalex   +1 more source

Tumor Microenvironment Triggered In Situ Coagulation of Supramolecularly Engineered Platelets for Precise Tumor Embolization

Advanced Science, EarlyView.
Occlusion of tumor blood vessels represents a promising yet challenging approach in cancer treatment. Herein, supramolecularly engineered platelets conjugated with morphology‐transformable nanoparticles is developed for precise tumor embolization. The engineered platelets actively accumulate at tumor sites following induced blood vessel injury.
Junyan Li, Ziyi Wang, Ruifeng Luo, Xingping Quan, Hong U Fong, Qian Cheng, Jianwen Wei, Leo Wang, Yonghua Zhao, Ruibing Wang   +9 more
wiley   +1 more source

Transcriptomic signatures in peripheral CD4⁺T-lymphocytes may reflect melanoma staging and immunotherapy responsiveness prior to ICI initiation. [PDF]

Front Immunol
Palli E, Lavigne M, Verginis P, Alissafi T, Anastasopoulou A, Lyrarakis G, Kirkwood JM, Gogas H, Ziogas DC.   +8 more
europepmc   +1 more source

Transcriptome Landscape of Cancer‐Associated Fibroblasts in Human PDAC

Advanced Science, EarlyView.
AP‐1 family members FOS and JUN regulate the malignant phenotype conversion of normal fibroblasts (NFs) to normal‐like cancer‐associated fibroblasts (nCAFs), while transforming growth factor‐β (TGFβ) and interferon‐γ (IFNγ) signals triggers the interconversion between classic myofibroblastic CAFs (myCAFs) and inflammatory CAFs (iCAFs), respectively ...
Mengyu Tao, Wenting Liu, Jianhua Chen, Rujiao Liu, Jianling Zou, Bo Yu, Chenchen Wang, Mingzhu Huang, Qingjian Chen, Zhe Zhang, Zhiyu Chen, Haoyu Sun, Cheng Zhou, Shuguang Tan, Yuxuan Zheng, Hongxia Wang   +15 more
wiley   +1 more source

The endocannabinoid anandamide prevents TH17 programming of activated T lymphocytes while preserving TH1 responses. [PDF]

Front Pharmacol
Kiprina A, Teichmann T, Martín Giménez VM, Xu W, Sailer F, Windbergs M, Manucha W, Weigert A, Brandes RP.   +8 more
europepmc   +1 more source