Results 281 to 290 of about 1,131,184 (349)

Effector-Memory γδ T Lymphocytes Predict CMV Disease After the Withdrawal of Prophylaxis in Kidney Transplant Recipients. [PDF]

Transpl Int
Abadie Y, Visentin J, Wojciechowski E, Charrier M, Déchanet-Merville J, Garrigue I, Blanco P, Merville P, Kaminski H, Couzi L.   +9 more
europepmc   +1 more source

CDK4/6 Inhibition Induces CD8+ T Cell Antitumor Immunity via MIF‐Induced Functional Orchestration of Tumor‐Associated Macrophages

Advanced Science, EarlyView.
CDK4/6 inhibition promotes CD8+ T cell expansion through tumor‐macrophage crosstalk by activating HIF‐1α and enhancing MIF‐CD44/CD74 signaling. This reprograms TAMs to boost MHC‐I antigen presentation, and CDK4/6 inhibitor‐trained M1 TAM supernatant therapy synergizes with low‐dose PD‐1 blockade to restore antitumor immunity.
Lin He, Yuzhong Peng, Lat‐lun Leong, Jingbo Zhou, Dongyang Tang, Weilu Wang, Xiaoran Wu, Josh haipeng Lei, Yongqin Ye, Yangyang Feng, Yunfeng Qiao, Xiangpeng Chu, Di Mu, Qi Zhao, Tzuming Liu, Yan Chen, Paul Kwonghang Tam, Chu‐Xia Deng   +17 more
wiley   +1 more source

Nasal Mucosa‐Derived Extracellular Vesicles as a Systemic Antiaging Intervention

Advanced Science, EarlyView.
This study shows that nasal mucosa‐derived extracellular vesicles (nmEVs) exert systemic anti‐ageing effects in mice by restoring circadian rhythm, suppressing cellular senescence, and improving cognitive function. In aged human bone marrow mesenchymal stem cells, nmEVs reverse senescence‐associated phenotypes and reactivate core clock gene expression.
Wentao Shi, Lu Bian, Mengyuan Yu, Jun Wang, Mingzhu Gao, Liping Shen, Xiao Zhang, Zhiliang Huang, Hong Tang, Long Lv, Yunduan Que, Zengli Miao, Xuechao Wu, Qing Wang, Xiaojie Lu   +14 more
wiley   +1 more source

HLA-DR expression in cytotoxic T lymphocytes: a key to boost the therapeutic potential of T cell-based strategies for breast cancer. [PDF]

Front Immunol
Salvador R, Correia BF, Grosa D, Martins T, Soares Baal SC, Saraiva DP, Cristóvão-Ferreira S, Pereira IL, Rebelo de Almeida C, Fior R, Jacinto A, Mathias C, Braga S, Cabral MG.   +13 more
europepmc   +1 more source

Red Blood Cells Internalize Extracellular DNA via Apoptotic Bodies with Clinical Relevance to Cancer Patients

Advanced Science, EarlyView.
Mature red blood cells (RBCs) can capture extracellular DNA, with short fragments homologous to cfDNA. This uptake is mediated by apoptotic bodies, which induce RBC oxidative stress, deformation, and accelerated in vivo clearance. The rbcDNA abundance correlates with tumor burden and therapeutic response, highlighting its potential as a liquid biopsy ...
Zihang Zeng, Zongbi Yi, Jing Hu, Jiali Li, Yu Xu, Xiuli Guo, Qian Ji, Kaixiang Feng, Ying Zhang, Sirui Bai, Yushuang Tan, Yufei Yan, Linzhi Han, Jing Jiang, Tengfei Wang, Xiang Wang, Ziqing Zhan, Ruiying Huang, Jinfang Zhang, Conghua Xie, Binghe Xu   +20 more
wiley   +1 more source

Novel Experimental Approach to Investigate Immune Control of Vascular Function: Co-culture of Murine Aortas With T Lymphocytes or Macrophages. [PDF]

Bio Protoc
Kress TC, Barris CT, Kennard S, Belin de Chantemèle EJ.   +3 more
europepmc   +1 more source

Cytotoxic Responses Mediated by NK Cells and Cytotoxic T Lymphocytes in Xenotransplantation. [PDF]

Transpl Int
Galdina V, Puga Yung GL, Seebach JD.
europepmc   +1 more source

T-lymphocytes suppression by CD14⁺ monocytes with high expression of ULK2 in patients with multiple myeloma. [PDF]

J Transl Med
Peng F, Liu Z, Jiang F, Li N, Wang H, Meng N, Liu H, Ding K, Fu R.   +8 more
europepmc   +1 more source

Erratum to "Global Trends in Research of Amino Acid Metabolism in T Lymphocytes in Recent 15 Years: A Bibliometric Analysis". [PDF]

J Immunol Res
europepmc   +1 more source

Infiltration characteristics and regulatory mechanisms of CD8⁺ T lymphocytes in solid tumors: spatial distribution, biological functions, and interactions with the immune microenvironment. [PDF]

Front Immunol
Ouyang P, Zhang J, He X, Yang C, Zeng D, Xu D.   +5 more
europepmc   +1 more source