Results 301 to 310 of about 1,131,184 (349)
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Annual Review of Immunology, 1983
observations and their interpretation becomes blurred with time. A re-evaluation of the data on CTL may become important at a time when the emphasis of the questions asked about these cells changes. We think the discovery of T-cell growth factor and the design of methods that have allowed the maintenance of CTL clones in permanent culture have ushered ...
M, Nabholz, H R, MacDonald
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observations and their interpretation becomes blurred with time. A re-evaluation of the data on CTL may become important at a time when the emphasis of the questions asked about these cells changes. We think the discovery of T-cell growth factor and the design of methods that have allowed the maintenance of CTL clones in permanent culture have ushered ...
M, Nabholz, H R, MacDonald
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Gut intraepithelial T lymphocytes
Current Opinion in Immunology, 1993The gut mucosa, given its length, contains a very large number of T lymphocytes in the Peyer's patches and disseminated all along the mucosa. The most conspicuous element of this last compartment, the gut intraepithelial lymphocytes, represents a population of CD8+ T lymphocytes as large as that found in the largest lymphoid organ, the spleen. In spite
D, Guy-Grand, P, Vassalli
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T Lymphocytes Degrade Fibronectin
Scandinavian Journal of Immunology, 1991Mononuclear cells cause disappearance of fibronectin synthesized and released by fibroblasts. This disappearance of extracellular fibroblast fibronectin is accompanied by the appearance of components of “lower” molecular weight indicating that a fibronectin‐degrading enzymatic activity is responsible for the effect. Additional support for the existence
S E, Bergström +2 more
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Early T Lymphocyte Progenitors
Annual Review of Immunology, 1996The earliest steps along the pathway leading to T cells in mice and humans are reviewed. These are the steps between the multipotent hemopoietic stem cell (HSC) and the fully committed precursors undergoing T cell receptor (TCR) gene rearrangement. At this level significant differences between adult and fetal lymphopoiesis have been demonstrated.
K, Shortman, L, Wu
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Extrathymic T-lymphocyte development
Experimental Hematology, 2003Chronic exposure to oncostatin M (OM) induces massive thymus-independent extrathymic T-cell development, which takes place solely in the lymph nodes (LN), probably because of the high density of OM receptor on LN postcapillary venules. In contrast to what is observed in other models of extrathymic T-cell development, the proportions of doublenegative ...
Marie-Eve, Blais +5 more
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T-Lymphocyte-fibroblast interactions
Biochemical Society Transactions, 1997At the end of the immune response, activated T-cells are cleared by apoptosis. T-cell apoptosis induced by cytokine deprivation can be inhibited by the addition of exogenous cytokines or by a fibroblast-derived survival factor. Under normal circumstances, fibroblast-mediated T-cell survival may allow persistence of a small number of primed T-cells in ...
J G, Crowston +3 more
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International Archives of Allergy and Immunology, 1995
Some of the key features of aging effects on T lymphocytes have been illuminated in the last few years from new angles. Experimental evidence indicates a profound increase in the proportion of memory versus naive types of T cells, a decline in the response to activation and in the capacity to enter the cycle, and decline in levels of IL-2, yet an ...
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Some of the key features of aging effects on T lymphocytes have been illuminated in the last few years from new angles. Experimental evidence indicates a profound increase in the proportion of memory versus naive types of T cells, a decline in the response to activation and in the capacity to enter the cycle, and decline in levels of IL-2, yet an ...
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T Lymphocytes and Autoimmunity
2018T lymphocytes play a central role in regulation of the immune system. Both effector and regulatory T cells work in equilibrium to provide optimal immune response against foreign pathogens. Normally, T cells do not react against self-antigens because of the presence of central and peripheral immunogenic tolerance.
Uqba, Khan, Hareem, Ghazanfar
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