Results 141 to 150 of about 2,240 (251)

Comparative Assessment of Methanol Production Pathways From Steel Mill Gases

Chemie Ingenieur Technik, EarlyView.
This publication reviews the process concepts and assessments for converting steel mill gases into sustainable methanol, focusing on energy efficiency, and the regulatory framework. From an energy perspective, the production of methanol from BOFG and H2 separated from coke oven gas is of particular interest.
Nils Tenhumberg, Stefan Schlüter, Matthias Krüger   +2 more
wiley   +1 more source

Adaptive Closed-Loop Control System for the Optimization of Tablet Manufacturing Processes. [PDF]

Pharmaceutics
Luo X, Zhong Z, Deng P, Fei Y, Cui P, Zhu W, Xiao Z, Wang T, Li L.   +8 more
europepmc   +1 more source

TutorBots im Chemieunterricht: Nutzung, Akzeptanz und Hürden aus Sicht von Lehrkräften

CHEMKON, EarlyView.
Der Einsatz von Künstlicher Intelligenz (KI) bietet großes Potenzial für einen adaptiven Naturwissenschaftsunterricht. In einer explorativen Studie wurde untersucht, wie Chemielehrkräfte zum Einsatz von TutorBots im Unterricht eingestellt sind. Dabei wurde sowohl die aktuelle Nutzungserfahrung im Bereich der Erstellung und Anwendung von TutorBots ...
Mathea Brückner, Christoph Thyssen, Johannes Huwer   +2 more
wiley   +1 more source

A Formulation-Process-Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route. [PDF]

Pharmaceutics
Liang Z, Tang X, Chen L, Liu Y, Zhao S, Ma X, Luo G, Xu B.   +7 more
europepmc   +1 more source

The Influence of Drosophila Spire and Myosin V During Mid‐Oogenesis Is Independent of Their Direct Interaction

Cytoskeleton, EarlyView.
ABSTRACT Cooperativity between cytoskeletal proteins is crucial for spatiotemporal coordination in biological processes, like oogenesis. In mammalian and Drosophila oogenesis, proper assembly and function of actin networks require coordination between actin assembly factors Spire and formins, as well as actin‐associated proteins like myosins and Rab ...
Joseph Y. Ong, Hannah M. Bailey, Emma Carley, Michelle Panzica, Merin Rixen, Neil Billington, Rong Liu, Margot E. Quinlan   +7 more
wiley   +1 more source

Polymorphism engineering of mefenamic acid for enhanced pharmacokinetic performance. [PDF]

EXCLI J
Prasher P, Sharma M.
europepmc   +1 more source

Transcranial Magnetic Stimulation as a Translational Biomarker in Early‐Phase Anti‐Seizure Medication Development: A Randomized, Double‐Blind, Placebo‐Controlled Study in Generalized Epilepsy

Clinical Pharmacology &Therapeutics, EarlyView.
One‐third of epilepsy patients remain treatment‐resistant, underscoring the need for novel anti‐seizure medications (ASMs) and reliable biomarkers of central target engagement. Cortical hyperexcitability is a hallmark of epilepsy, making excitability a valuable pharmacodynamic biomarker for early‐phase drug development supporting go/no‐go decision ...
Catherine M. E. de Cuba, Titia Q. Ruijs, Annika A. de Goede, Robert J. Doll, Maria Juachon, Michel J. A. M. van Putten, Geert Jan Groeneveld, Jules A. A. C. Heuberger   +7 more
wiley   +1 more source

Chewable Tablets for Precise Unit Dosing of Animals. [PDF]

J Pharm Innov
Landes RE, Valekar P, Abbas M, DeLoatch KA, Schreiber JB, Buckner IS, Leak RK.   +6 more
europepmc   +1 more source

Identification of a Functional CYP2C8 Variant Allele that Alters Splicing, Reduces Protein Expression, and Increases Drug Exposure

Clinical Pharmacology &Therapeutics, EarlyView.
This study investigated genetic determinants of the pharmacokinetics of the CYP2C8 index drugs repaglinide and gemfibrozil, and their interaction in healthy participants. Sequencing data from a study with montelukast revealed a novel functional CYP2C8 allele (rs2071426, CYP2C8*19), predicted to create an intronic splice donor site.
Anssi J. H. Mykkänen, Päivi Hirvensalo, Kathrin Klein, Dorota Kaminska, Markus Grube, Tuija Tapaninen, Johanna I. Kiiski, Mikko Neuvonen, Ville T. Männistö, Jussi Pihlajamäki, Mladen Tzvetkov, Matthias Schwab, Aleksi Tornio, Janne T. Backman, Mikko Niemi   +14 more
wiley   +1 more source

Oral Tablet Formulations with Lactoferrin, a Cohesive Biomacromolecule. [PDF]

Pharmaceutics
Rogers TL, Horton AJ, Watson T, Robart S, DeFrancesco B, Bishop H, Tocce E.   +6 more
europepmc   +1 more source