Biotechnology and Applied Biochemistry, EarlyView.ABSTRACT Neurodegenerative diseases, including Alzheimer's disease (AD) and Parkinson's disease (PD), are characterized by the pathological aggregation of specific proteins such as amyloid beta (Aβ) and α‐synuclein, respectively. Early detection of these protein aggregates in biological fluids could facilitate timely diagnosis and therapeutic ...
Alexandra Dybala +4 more
wiley +1 more source
Modeling of physical-mechanical and microbiological properties of tablets made of complex fluidized bed granules containing living yeast cells using common mixing rules. [PDF]
Int J Pharm XVorländer K +4 more
europepmc +1 more source
Biofuels, Bioproducts and Biorefining, EarlyView.Abstract The development of renewable energy sources is important in order to achieve the United Nations Sustainable Development Goals (SDGs). Waste cooking oil (WCO) is a promising feedstock for biodiesel production through transesterification. Heterogeneous bifunctional catalysts offer a sustainable alternative to conventional homogeneous bases such ...
Frederick Jit Fook Phang +9 more
wiley +1 more source
Prescribing competence: The pros and cons of different methods for assessment
British Journal of Clinical Pharmacology, EarlyView.Evaluating a medical graduate’s competence in rational prescribing is challenging. With the aim to guide and inspire teachers, this narrative review explores different methods that can be used to assess prescribing competence. Each method has its own advantages and disadvantages, and thus a mix of different assessment methods is needed throughout the ...
David J. Brinkman +3 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Cannabidiol (CBD), the main non‐intoxicating compound from the cannabis plant, is regularly used by patients with chronic pain who also take analgesics. CBD has previously been shown to inhibit CYP‐mediated drug metabolism. This study aimed to characterize the potential pharmacokinetic interaction of CBD with amitriptyline and tramadol ...
Andriy A. Gorbenko +9 more
wiley +1 more source
Design, Development and Evaluation of Orally Disintegrating Mini-tablets (ODMTs) Containing Cefixime for Paediatric Use: A Novel Approach. [PDF]
Turk J Pharm SciSetty V, Joshi VG, Chandrasekar SB.
europepmc +1 more source
Paediatric development of radiopharmaceutical imaging agents and radioligand therapeutics
British Journal of Clinical Pharmacology, EarlyView.Abstract This review focuses on the development of radiopharmaceutical imaging agents and radioligand therapeutics for paediatric use. Nuclear medicine plays an important role in the diagnosis and treatment of various childhood conditions, including cancers, infections and brain disorders.
Justin L. Hay +5 more
wiley +1 more source
Adaptive Closed-Loop Control System for the Optimization of Tablet Manufacturing Processes. [PDF]
PharmaceuticsLuo X +8 more
europepmc +1 more source
A Formulation-Process-Product Integrated Design Method for Accelerating Pharmaceutical Tablet Development via the High-Shear Wet Granulation and Tableting Route. [PDF]
PharmaceuticsLiang Z +7 more
europepmc +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Aims Chemical Adherence Testing (CAT) is gaining prominence as a reliable and valid clinical method to detect whether antihypertensive agents are being taken as prescribed. This study aimed to explore clinicians' attitudes and perspectives on the clinical use of CAT.
Roshan Shahab +2 more
wiley +1 more source