Results 221 to 230 of about 7,179 (272)

Implementation of OMOP and ConcePTION Common Data Models in CPRD GOLD: Risk of Bleeding and Cardiovascular Outcomes From Anticoagulant Use

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
The impact of the choice of common data model (CDM) approach on the study results in a real‐world evidence (RWE) study is unknown. We aimed to determine potential differences in the results of an RWE study when data were mapped to two different CDMs, ConcePTION and OMOP. With the same instance of CPRD GOLD, data were mapped to both CDMs. Using the same
Nicholas B. Hunt   +8 more
wiley   +1 more source

Advances in Human Mass Balance Studies: An IQ Consortium Perspective on Current Practices and Emerging Trends

open access: yesClinical Pharmacology &Therapeutics, EarlyView.
Human radiolabeled mass balance studies are crucial for comprehensively characterizing the absorption, distribution, metabolism, and excretion (ADME) of investigational drugs, providing essential data for drug development, regulatory evaluation, and product labeling.
Jason Boer   +24 more
wiley   +1 more source

Development of Orally Disintegrating Tablets of Standardized <i>Rhodiola rosea</i> Extract. [PDF]

open access: yesPharmaceuticals (Basel)
Brante O   +6 more
europepmc   +1 more source

Digital Transformation in Work Integration Social Enterprises: Leadership Strategies and the Role of Internal Stakeholders

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Digital transformation is increasingly reshaping how social enterprises organize work, engage stakeholders, and pursue social value. While prior research has examined digitalization in hybrid organizations, limited attention has been paid to how responsibility for inclusive digital transformation is enacted internally.
Riccardo Maiolini   +2 more
wiley   +1 more source

Journey of a pill. [PDF]

open access: yesCan Fam Physician
Kaur H   +7 more
europepmc   +1 more source

Secondary schools' preparation for roll‐out of Curriculum for Wales: Case studies of approaches to health and well‐being in the context of national education system reform

open access: yesThe Curriculum Journal, EarlyView.
Abstract Schools are increasingly positioned as key settings for promoting health behaviours and well‐being. Curriculum for Wales (CfW) represents major national reform of the Welsh education system, placing unprecedented focus on health and well‐being for learners in compulsory education (aged 3–16).
Rochelle Embling   +3 more
wiley   +1 more source

Innovative Galenic Formulation of Prussian Blue Tablets: Advancing Pharmaceutical Applications. [PDF]

open access: yesPharmaceuticals (Basel)
Martínez-Alonso B   +3 more
europepmc   +1 more source

Patterns of Uptake, Engagement, and Attrition in Randomized Controlled Trials of Digital Interventions for Eating Disorders: A Systematic Review and Meta‐Analysis

open access: yesInternational Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This review aimed to quantify rates of uptake (treatment initiation), adherence (program completion), and attrition (study dropout) in randomized trials of digital eating disorder (ED) interventions, and to synthesize engagement reporting practices, their consistency, and associations with clinical outcomes. Methods Randomized trials
Claudia Liu   +4 more
wiley   +1 more source

Spatial and Temporal Visualization of Polymorphic Transformations in Pharmaceutical Tablets. [PDF]

open access: yesAngew Chem Int Ed Engl
Gasol-Cardona J   +9 more
europepmc   +1 more source

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