Results 1 to 10 of about 30,871 (339)

Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation [PDF]

Frontiers in Chemistry, 2023
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Wenbo Zou, Wenbo Zou, Wanhui Liu, Changqin Hu   +3 more
doaj   +3 more sources

Formulation study of duloxetine hydrochloride enteric-coated tablets

SN Applied Sciences, 2023
During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
Jiang Guowei, Cao Zhihui, Zhang Yuhan, Meng Yongjun, Yi Qingqing   +4 more
doaj   +3 more sources

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy

International Journal of Analytical Chemistry, 2021
Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti-inflammatory and analgesic drugs. The purpose of the present study was to formulate and evaluate enteric-coated tablets for SRP and investigate their stability ...
Vijay Kumar Panthi, Saurav Kumar Jha, Raghvendra Chaubey, Rudra Pangeni   +3 more
doaj   +2 more sources

Pharmacokinetic Study of Enteric-Coated Sustained-Release Aspirin Tablets in Healthy Chinese Participants

Drug Design, Development and Therapy, 2023
Duanduan Cong,1 Wenyuan Qi,1 Xiaohui Liu,1 Xiaoyu Xu,1 Lingyun Dong,2 Wei Xue,1,* Kexin Li1,* 1Clinical Trial Center, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences, Beijing ...
Cong D, Qi W, Liu X, Xu X, Dong L, Xue W, Li K   +6 more
doaj   +2 more sources

Development of a particle swarm optimization-backpropagation artificial neural network model and effects of age and gender on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population

BMC Pharmacology and Toxicology, 2022
Background The effects of age and gender were explored on pharmacokinetics study of omeprazole enteric-coated tablets in Chinese population and a plasma concentration prediction model was developed.
Yichao Xu, Jinliang Chen, Dandan Yang, Yin Hu, Bo Jiang, Zourong Ruan, Honggang Lou   +6 more
doaj   +2 more sources

Enteric-Coated Cologrit Tablet Exhibit Robust Anti-Inflammatory Response in Ulcerative Colitis-like In-Vitro Models by Attuning NFκB-Centric Signaling Axis

Pharmaceuticals, 2022
Ulcerative colitis (UC) is an inflammatory bowel disease that affects the patients’ colorectal area culminating in an inflamed ‘leaky gut.’ The majority of UC treatments only provide temporary respite leading to its relapse.
Acharya Balkrishna, Rani Singh, Vivek Gohel, Sagar Arora, Rishabh Dev, Kunal Bhattacharya, Anurag Varshney   +6 more
doaj   +2 more sources

Evaluation of pharmacokinetics and relative bioavailability of pentoxifylline and its metabolite in beagle dogs following different formulations [PDF]

Frontiers in Pharmacology
A single-oral-dose, two-period cross-over study with a 5-day washout period under fed condition was conducted in six beagle dogs to explore the pharmacokinetic characteristics and relative bioavailability between sustained-release (SR) tablets and ...
Yuxiang Xu, Hongxin Qie, Haopeng Zhao, Wenlin Gong, Peiyuan Wang, Xiaonan Gao, Jinglin Gao, Zhangying Feng, Mingxia Wang   +8 more
doaj   +2 more sources

In Silico Evaluation of the Biopharmaceutical and Pharmacokinetic Behavior of Metronidazole from Coated Colonic Release Matrix Tablets [PDF]

Pharmaceutics
Background: Physiologically based biopharmaceutics modeling (PBBM) models can help to predict drug release and in vivo absorption behaviors. Colon drug delivery systems have gained interest over the past few years due to the advantages they provide in ...
Roberto Arévalo-Pérez, Cristina Maderuelo, José M. Lanao   +2 more
doaj   +2 more sources

Case report: Alectinib-associated intestinal ulceration and colitis in a patient with non-small cell lung cancer and effective treatment with Mesalazine [PDF]

Pathology and Oncology Research
BackgroundAlectinib is effective in extending the survival of patients with anaplastic lymphoma kinase (ALK)-positive non-small cell lung cancer (NSCLC) and generally has manageable side effects.
Zijian Qiu, Fei Ke, Xiaoping Zhu
doaj   +2 more sources

Preformulation Studies for Generic Omeprazole Magnesium Enteric Coated Tablets

BioMed Research International, 2015
Preformulation is an important step in the rational formulation of an active pharmaceutical ingredient (API). Micromeritics properties: bulk density (BD) and tapped density (TD), compressibility index (Carr's index), Hauser's ratio (H), and sieve ...
C. Migoha, M. Ratansi, Elingiringa Amos Kaale, G. Kagashe   +3 more
semanticscholar   +4 more sources