Results 1 to 10 of about 718 (123)

Formulation study of duloxetine hydrochloride enteric-coated tablets

SN Applied Sciences, 2023
During storage, duloxetine hydrochloride may have an unexpected cross reaction with enteric coated acrylic resin, which may affect the product quality.
Jiang Guowei, Cao Zhihui, Zhang Yuhan, Meng Yongjun, Yi Qingqing   +4 more
doaj   +2 more sources

Development of Enteric-coated Tablets of Sodium 4,4'-(propnadiamido)dibenzoate

Разработка и регистрация лекарственных средств, 2022
Introduction. Enteric coat have a wide range of functions: from protecting the API from the adverse effects of the acidic environment of the stomach to targeted delivery to certain parts of the intestine in order to increase the effectiveness of the drug.
Ju. M. Kotsur, E. V. Flisyuk, I. A. Narcevich   +2 more
doaj   +1 more source

Development of Duloxetine Hydrochloride Tablets for Delayed and Complete Release Using Eudragit L 100

International Journal of Polymer Science, 2021
The purpose of the research was to optimize the preparation of duloxetine hydrochloride (duloxetine HCl) delayed release tablets. Duloxetine HCl produces a toxic substance called alpha-naphthol when duloxetine HCl is in contact with gastric fluid.
M. Yasmin Begum, Ali Alqahtani, Mohammed Ghazwani, Noura Abdullah Alhamood, Umme Hani, Avanthi Jajala, Mohamed Rahamathulla   +6 more
doaj   +1 more source

Characterization of enteric-coated erythromycin tablets by Raman mapping and its pharmaceutical evaluation

Frontiers in Chemistry, 2023
Enteric tablet coating thickness is a critical quality attribute of the coating process that can affect dissolution behavior in vitro as well as release in vivo.
Wenbo Zou, Wenbo Zou, Wanhui Liu, Changqin Hu   +3 more
doaj   +1 more source

Oral Delivery of Niclosamide as an Amorphous Solid Dispersion That Generates Amorphous Nanoparticles during Dissolution

Pharmaceutics, 2022
Niclosamide is an FDA-approved anthelmintic that is being studied in clinical trials as a chemotherapeutic and broad-spectrum antiviral. Additionally, several other applications are currently in the preclinical stage.
Miguel O. Jara, Zachary N. Warnken, Sawittree Sahakijpijarn, Rishi Thakkar, Vineet R. Kulkarni, Dale J. Christensen, John J. Koleng, Robert O. Williams   +7 more
doaj   +1 more source

Formulation and development of Serratiopeptidase enteric coated tablets and analytical method validation by UV Spectroscopy

International Journal of Analytical Chemistry, 2021
Serratiopeptidase (SRP) is a proteolytic enzyme that emerged as one of the most potent anti-inflammatory and analgesic drugs. The purpose of the present study was to formulate and evaluate enteric-coated tablets for SRP and investigate their stability ...
Vijay Kumar Panthi, Saurav Kumar Jha, Raghvendra Chaubey, Rudra Pangeni   +3 more
doaj   +1 more source

Systems Biology and Peptide Engineering to Overcome Absorption Barriers for Oral Peptide Delivery: Dosage Form Optimization Case Study Preceding Clinical Translation

Pharmaceutics, 2023
Oral delivery of peptides and biological molecules promises significant benefits to patients as an alternative to daily injections, but the development of these formulations is challenging due to their low bioavailability and high pharmacokinetic ...
Puneet Tyagi, Chandresh Patel, Kimberly Gibson, Fiona MacDougall, Sergei Y. Pechenov, Sarah Will, Jefferson Revell, Yue Huang, Anton I. Rosenbaum, Kemal Balic, Umar Maharoof, Joseph Grimsby, J. Anand Subramony   +12 more
doaj   +1 more source

In Vitro Release Study on Capsules and Tablets Containing Enteric - Coated Granules Prepared by Wet Granulation

Iraqi Journal of Pharmaceutical Sciences, 2017
Wet granulation method was used instead of conventional pan coating  or fluidized –bed coating technique to prepare enteric-coated diclofenac sodium granules, using ethanolic solution of EudragitTM L100 as coating, binding and granulating agent ...
Eman B. H. Al-Khedairy
doaj   +3 more sources

Comparison of Upper Gastrointestinal Toxicity of Enteric-Coated Prednisolone Versus Non-EntericCoated Prednisolone Among Patients Managed at the Rheumatology Department

Pakistan Armed Forces Medical Journal, 2023
Objective: To compare the upper gastrointestinal toxicity of enteric-coated Prednisolone versus non-enteric-coated Prednisolone among patients managed at the rheumatology department. Study Design: Cross-sectional study. Place and Duration of Study:
Mohsin Shakoor Malik, Amer Fakhr, Farzana Hakim, Ahsan Amer   +3 more
doaj   +1 more source

3D Printing for a novel Enteric Coated Ibuprofen Tablets

British Journal of Pharmacy, 2023
3D printing has the potential to play a significant role in pharmaceutical research by optimizing medication usage and minimizing adverse effects through the creation of personalised dosage forms. However, various obstacles hinder the full utilisation of
Ahmed Nassar, Yasir Karkar, Ahmed M Faheem   +2 more
doaj   +1 more source