Results 51 to 60 of about 4,527 (242)

Preformulation Studies for Generic Omeprazole Magnesium Enteric Coated Tablets

BioMed Research International, 2015
Preformulation is an important step in the rational formulation of an active pharmaceutical ingredient (API). Micromeritics properties: bulk density (BD) and tapped density (TD), compressibility index (Carr’s index), Hauser’s ratio (H), and sieve analysis were performed in order to determine the best excipients to be used in the formulation development
Migoha, C. O., Ratansi, M., Kaale, E., Kagashe, G.   +3 more
openaire   +2 more sources

Skin‐Interfaced Therapeutic Patches for Wound Fluid Management and Transdermal Drug Delivery

Advanced Healthcare Materials, EarlyView.
This study presents an integrated skin‐interfaced device combining microfluidics, hydrogel film technology, flexible electronics, and iontophoresis‐based transdermal delivery of PDRN to enhance wound healing. The device effectively manages wound fluid, maintains optimal moisture, and non‐invasively delivers therapeutic drugs.
Dongjun Han, Donghyun Kim, Haram Lee, Dong‐Wook Park, Sung Soo Kwak, Joohee Kim   +5 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

Advanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba, Abdessalem Rekiki, Cécile Loubière, Sabine Kuchler‐Bopp, Lauriane Petit, Cynthia Calligaro, Derry Mercer, Aurore Gaudin, Naomi Canourgues, Emilie Adicéam, Benoit Beitz, Jeremy Welsch, Annabelle Vigué, Markus j. Kettel, Michael Karl, Chloé Guilbaud‐Chéreau, Philippe Lavalle, Nihal Engin Vrana, Skander Hathroubi   +18 more
wiley   +1 more source

A New 3D Colon on a Chip to Decipher the Influence of Mechanical Forces on the Physiological Cellular Ecosystem

Advanced Healthcare Materials, EarlyView.
To dissect how mechanical forces influence intestinal physiology, we developed a stretchable 3D colon‐on‐chip that integrates tunable topography, stiffness and peristalsis‐like motion within a physiologically relevant microenvironment. We showed that stretching is a dominant factor governing epithelial behavior, markedly enhancing proliferation and ...
Moencopi Bernheim‐Dennery, Lauriane Gérémie, Julie Brun, Lucas Chassatte, Giacomo Gropplero, Réda Bouras, Jieun Choo, Bertrand Cinquin, Alba Marcellan, Danijela Matic Vignjevic, Stéphanie Descroix   +10 more
wiley   +1 more source

Enteric coating of ibuprofen tablets (200 mg) using an aqueous dispersion system

Brazilian Journal of Pharmaceutical Sciences, 2010
Ibuprofen is a propionic acid derivative that belongs to the class NSAIDs. Major adverse reactions associated with Ibuprofen are related to GIT and include peptic and mucosal ulcers, dyspepsia, severe gastric pain and bleeding, that results in excessive ...
Rabia Bushra, Muhammad Harris Shoaib, Nousheen Aslam, Zafar Alam Mehmood, Durriya Hashmat   +4 more
doaj   +1 more source

Nateglinide Controlled Release Tablet Containing Compressionable Enteric Coated Granules

CHEMICAL & PHARMACEUTICAL BULLETIN, 2010
We designed a single unit type controlled release tablet containing nateglinide to decrease both postprandial blood glucose level (PBG) and fasting blood glucose level (FBG) in normal beagle dogs. The tablet contains 60 mg of nateglinide in an immediate release portion, and 90 mg of nateglinide in a controlled release portion.
Chisato, Makino, Hidetoshi, Sakai, Akira, Yabuki   +2 more
openaire   +3 more sources

Spatially‐Controlled Planar Guided Crystallization of Low‐Loss Phase Change Materials for Programmable Photonics

Advanced Materials, EarlyView.
The concept of spatially‐controlled planar guided crystallization is a novel method for programming the growth of optically homogeneous low‐loss Sb2S3 phase‐change material (PCM), leveraging the directional crystallization within confined channels.
Fouad Bentata, Arnaud Taute, Capucine Laprais, Régis Orobtchouk, Eva Kempf, Alban Gassenq, Yves Pipon, Michele Calvo, Valérie Martinez, Stéphane Monfray, Guillaume Saint‐Girons, Nicolas Baboux, Hai Son Nguyen, Xavier Letartre, Lotfi Berguiga, Patrice Genevet, Sébastien Cueff   +16 more
wiley   +1 more source

Atomistic Mechanisms Triggered by Joule Heating Effects in Metallic Cu‐Bi Nanowires for Spintronics

Advanced Materials, EarlyView.
Bi doped metallic Cu nanowires are promising for spintronics thanks to the stabilization of a giant spin Hall effect. However, heat resulting from current injection forces Bi to leave solution, forcing segregation into monoatomic decorations which evolve into coherent crystalline aggregates.
Alejandra Guedeja‐Marrón, Juan Ignacio Beltrán, Matilde Saura‐Múzquiz, Paolo Perna, M. Carmen Muñoz, Lucas Pérez, Maria Varela   +6 more
wiley   +1 more source

Multiphysics‐Driven Assembly of Biomimetic Vesicles

Advanced Materials, EarlyView.
Artificial extracellular vesicles, derived from cell membranes, are manufactured using a multiphysics‐integrated microfluidic platform that combines nanoknife membrane rupture, herringbone chaotic mixing, and acoustothermal modulation. This standardizable workflow enables the predictable control of vesicle formation and therapeutic loading, while ...
Timofei Solodko, Ian Gimino, Aastha Chandiwala, Bayan Alkotoub, Ali Bashiri Dezfouli, Heiko Reith, Asjad Bakhtiar, Rojda Hicsanmaz, Johann Brenner, Christoph J. O. Kaiser, Elena Belli, Shilpi Pandey, Samuel D. Rabkin, Kornelius Nielsch, Gabriele Multhoff, Oliver Hayden, Morteza Hasanzadeh Kafshgari   +16 more
wiley   +1 more source

Treatment with Plasma Activated (Salt) Water Sterilizes Macromolecular Coatings While Maintaining Their Integrity and Functionality

Advanced Materials Interfaces, EarlyView.
PDMS samples were covalently coated with mucin glycoproteins and then treated with either plasma activated water (PAW) or saline (PAS) as a means of disinfection. The samples could be successfully sterilized without compromising the structural integrity or functionality of those coatings.
Bernardo Miller Naranjo, Markus Ahrens, Ádám Nemes, Petra Mela, Oliver Lieleg   +4 more
wiley   +1 more source