Results 41 to 50 of about 320,993 (294)
Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Design of experiments methodology in studying near-infrared spectral information of model intact tablets : simultaneous determination of metoprolol tartrate and hydrochlorothiazide in solid dosage forms and powder compressibility assessment using near-infrared spectroscopy [PDF]
, 2015 Near-infrared spectroscopy (NIRS) is applied in pharmaceutical industry for monitoring drug content during tablet manufacturing process. NIRS method, once developed and validated, is used over years and it is of critical importance to insure method ...
Vranic, Branko Z.
core +1 more source
Improving Learning Outcomes: The iPad and Preschool Children with Disabilities
Frontiers in Psychology, 2017 The digital age has reached early childhood, and the use of touch screens by young children is common place. Research on the use of touch screen tablets with young children is becoming more prevalent; however, less information is available on the use of ...
Linda Chmiliar
doaj +1 more source
Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Especial para tablets do caderno Donna DC [PDF]
, 2014 TCC (graduação) - Universidade Federal de Santa Catarina. Centro de Comunicação e Expressão. Jornalismo.A indústria têxtil e a moda são segmentos importantes na economia de Santa Catarina, com marcas de relevância no âmbito nacional como Colcci ...
Andrade, Bruna Gonçalves
core
Reprogramming tumor cells with LCOR mRNA nanotherapy to enhance immunotherapy
Molecular Oncology, EarlyView.LCOR (Ligand‐dependent corepressor) mRNA encapsulated in polymeric nanoparticles restores LCOR activity in tumor cells, constraining aggressive tumor cell states and increasing tumor immunogenicity. This reprogramming makes tumor cells more vulnerable to T‐cell attack and enhances their response to immune‐checkpoint immunotherapy.
Gabriel Serra‐Mir +9 more
wiley +1 more source
From compressibility to structural investigation of sodium dodecyl sulphate — Part 1: Powder and tablet physico-chemical characteristics [PDF]
, 2007 As a part of a study on detergent tablets, investigations were carried out to elucidate the compression behavior of a powdered surfactant, sodium dodecyl sulphate (SDS), based on a comparison with the main component of the formulation, i.e.
Pouget, Christelle +8 more
core +1 more source
Tecnología, Ciencia y Educación, 2021 Esta propuesta de investigación tiene como principal objetivo profundizar en la repercusión que tiene el uso de las tablets como herramienta en el aprendizaje del alumnado desde la perspectiva docente y familiar del centro concertado Vivaldi.
Lara Alcántara González +3 more
doaj +1 more source
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
Investigation of Formulation and Process of Lyophilised Orally Disintegrating Tablet (ODT) Using Novel Amino Acid Combination [PDF]
, 2010 Lyophilised orally disintegrating tablets (ODTs)have achieved a great success in overcoming dysphagia associated with conventional solid dosage forms.
Mohammed, Afzal-Ur-Rahman +19 more
core +1 more source