Results 41 to 50 of about 697,298 (306)
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
Image and interpretation using artificial intelligence to read ancient Roman texts [PDF]
, 2005 The ink and stylus tablets discovered at the Roman Fort of Vindolanda are a unique resource for scholars of ancient history. However, the stylus tablets have proved particularly difficult to read.
Robertson, P, Terras, M
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Writing medium’ s impact on memory: A comparison of paper vs. tablet
Technology in Language Teaching & Learning, 2021 Studies comparing writing media typically compare different modes of writing (e.g., keyboard typing vs. writing, smartphone tapping vs. writing, etc.).
Bradford J. Lee
doaj +1 more source
Theoretical characterization of a model of aragonite crystal orientation in red abalone nacre
, 2009 Nacre, commonly known as mother-of-pearl, is a remarkable biomineral that in red abalone consists of layers of 400-nm thick aragonite crystalline tablets confined by organic matrix sheets, with the $(001)$ crystal axes of the aragonite tablets oriented ...
Chandler David +11 more
core +1 more source
Molecular Oncology, EarlyView.We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Tablet Splitting: Influence of Technique and Tablet Format
, 2022 Tablet splitting is a commonly used technique to obtain half of the dose or to facilitate tablet intake. However, there is a risk of not obtaining the correct dose and the efficacy depends on factors such as splitting method and tablet characteristics.
Alexandre, Ana +2 more
openaire +2 more sources
Single‐molecule DNA flow‐stretch assays for high‐throughput DNA–protein interaction studies
FEBS Open Bio, EarlyView.We describe an optimised single‐molecule DNA flow‐stretch assay that visualises DNA–protein interactions in real time. Linear DNA fragments are tethered to a surface and stretched by buffer flow for fluorescence imaging. Using λ and φX174 DNA, this protocol enhances reproducibility and accessibility, providing a versatile approach for studying diverse ...
Ayush Kumar Ganguli +8 more
wiley +1 more source
The application of povidone in the preparation of modified release tablets
Current Issues in Pharmacy and Medical Sciences, 2016 The aim of the study was to investigate the modified release of a model substance, of tablets containing different types of Kollidon and particular additives.
Kasperek Regina +5 more
doaj +1 more source
Improving Learning Outcomes: The iPad and Preschool Children with Disabilities
Frontiers in Psychology, 2017 The digital age has reached early childhood, and the use of touch screens by young children is common place. Research on the use of touch screen tablets with young children is becoming more prevalent; however, less information is available on the use of ...
Linda Chmiliar
doaj +1 more source