Results 61 to 70 of about 509,994 (339)

De la generación del pulgar a la generación del índice From thumb's generation to forefinger's generation

open access: yesRevista Teknokultura, 2012
La aparición en 2010 de las tablets y el uso espontáneo que los niños desde primera infancia hacen de ellos, nos lleva a replantearnos si no estaremos delante de una nueva generación, la Generación del índice, frente a la llamada, hace unos años ...
Henar León Barroso
doaj  

IoT/Sensor-Based Infrastructures Promoting a Sense of Home, Independent Living, Comfort and Wellness

open access: yesSensors, 2019
This paper presents the results of three interrelated studies concerning the specification and implementation of ambient assisted living (AAL)/Internet of Things (IoT)/sensor-based infrastructures, to support resident wellness and person-centered care ...
Joan Cahill   +5 more
doaj   +1 more source

3D Printed Polyvinyl Alcohol Tablets with Multiple Release Profiles

open access: yesScientific Reports, 2019
The aim of this study was to explore the feasibility of using different 3D printed internal geometries as tablet formulations to obtain controlled release profiles. In order to obtain controllable release profiles, three types of tablet models (Cylinder,
Xiaowen Xu   +4 more
semanticscholar   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Development of Dihydroquercetin-based Oral tablets and Evalution of the General Toxic Effect

open access: yesРазработка и регистрация лекарственных средств, 2022
Introduction. Dihydroquercetin is a flavonoid from the group of flavanonols with a wide spectrum of pharmacological activity. Its positive therapeutic profile was established for chronic venous insufficiency, chronic obstructive pulmonary disease and ...
S. A. Abdulrazzak   +10 more
doaj   +1 more source

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

open access: yesMolecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma   +9 more
wiley   +1 more source

Material Considerations for Fused-Filament Fabrication of Solid Dosage Forms

open access: yesPharmaceutics, 2018
Material choice is a fundamental consideration when it comes to designing a solid dosage form. The matrix material will ultimately determine the rate of drug release since the physical properties (solubility, viscosity, and more) of the material control ...
Evert Fuenmayor   +6 more
doaj   +1 more source

Development of the Tablet Dosage Form Composition for the Inductor of Hepatocytes Monooxygenase System Based on 6,8-dimethyl-2-piperidinomethyl-2,3-dihydrothiazolo[2,3-F]xanthine

open access: yesРазработка и регистрация лекарственных средств, 2023
Introduction. Cytochromes P450 depression is the reason for the low effectiveness of etiotropic and pathogenetic therapy of hepatitis. Recent experimental and clinical studies demonstrated the need for use of inducers of hepatocytes monooxygenase system ...
A. I. Petrakov   +5 more
doaj   +1 more source

Loss of primary cilia promotes EphA2‐mediated endothelial‐to‐mesenchymal transition in the ovarian tumor microenvironment

open access: yesMolecular Oncology, EarlyView.
Loss of primary cilia in endothelial cells promotes EndMT and vascular abnormalities in the ovarian tumor microenvironment through EphA2 activation. Using human samples, in vitro models, and endothelial‐specific Kif3a‐knockout mice, we show that primary cilia loss drives the acquisition of cancer‐associated fibroblast‐like phenotypes, thereby ...
Jin Gu Cho   +11 more
wiley   +1 more source

Quality Assessment of Seven Brands of Albendazole Tablets Marketed in Yemen

open access: yesYemeni Journal for Medical Sciences, 2018
Objective: To assess certain quality control parameters for seven brands of albendazole tablets obtained from different retail pharmacies. Methods: The physicochemical properties and active ingredientsofseven randomly selectedbrands of albendazole ...
Gamil Q. Othman
doaj   +1 more source

Home - About - Disclaimer - Privacy