Results 31 to 40 of about 116,048 (260)

La aplicación OpEdu como método de integración de las tecnologías en las formas organizativas del proceso de enseñanza – aprendizaje

Modelling in Science Education and Learning
Lograr transformaciones cualitativas en el proceso de enseñanza - aprendizaje como consecuencia de un amplio y generalizado empleo de las TIC ha sido una de las premisas en la actual transformación curricular llevada a cabo en la Educación Superior ...
M. Pérez Martínez, J. Ramos Guardarrama   +1 more
doaj   +1 more source

Fundamentals of Thermal Transport and Energy Conversion in Ultra‐High Temperature Ceramics: From Microscale Mechanisms to Macroscopic Properties

Advanced Science, EarlyView.
This review critically examines thermal transport and radiative properties of ultra‐high temperature ceramics for hypersonic flight, advanced nuclear systems, and next‐generation energy conversion devices. It explores phonon–photon–electron interactions, microstructural engineering, thermoelectric conversion, and machine learning‐accelerated multiscale
Zhipeng Pei, Yue Li, Jiayu Xing, Yue Zhu, Ru Zhang, Huan Wu, Zihao Qin, Gang Pei, Man Li   +8 more
wiley   +1 more source

Association of Total Airway Count on Computed Tomography with Pulmonary Function Decline in Early-Stage COPD: A Population-Based Prospective Cohort Study

International Journal of COPD, 2021
Fan Wu,1,2,* Changbin Jiang,1,* Yumin Zhou,1,2,* Youlan Zheng,1,* Heshen Tian,1 Haiqing Li,1 Zhishan Deng,1 Ningning Zhao,1 Huai Chen,3 Pixin Ran1,2 1National Center for Respiratory Medicine, State Key Laboratory of Respiratory Disease ...
Wu F, Jiang C, Zhou Y, Zheng Y, Tian H, Li H, Deng Z, Zhao N, Chen H, Ran P   +9 more
doaj  

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

Advanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu, Chao Xu, Jun Jiang, Limin He, Yike Zhou, Zhengxuan Li, Yu Li, Keying Zhang, Fa Yang, Tong Lu, Hongtao Song, Hai Zhu, Zhihao Hu, Xiaolong Zhao, Kai Gan, Hongji Li, Bo Yang, Rui Zhang, Weihong Wen, Donghui Han, Weijun Qin   +20 more
wiley   +1 more source

Comparative Study of the Effects of Atypical Antipsychotic Drugs on Plasma and Urine Biomarkers of Oxidative Stress in Schizophrenic Patients

Neuropsychiatric Disease and Treatment, 2021
Anna Dietrich-Muszalska,1 Joanna Kolodziejczyk-Czepas,2 Pawel Nowak2 1Medical University of Lodz, Department of Biological Psychiatry and Neurophysiology, Lodz, Poland; 2University of Lodz, Department of General Biochemistry, Lodz, PolandCorrespondence ...
Dietrich-Muszalska A, Kolodziejczyk-Czepas J, Nowak P   +2 more
doaj  

Intrinsically Mitochondria‐Targeting Nanozyme via Coordination‐Assembly of Natural Quercetin for Cascade Antioxidant Therapy of Cerebral Ischemia‐Reperfusion Injury

Advanced Science, EarlyView.
This study uncovers that quercetin naturally targets mitochondria. By coordinating quercetin with Fe3+, we engineer an ultrasmall cascade nanozyme (MCN) with superoxide dismutase‐catalase activities. MCN crosses the damaged blood–brain barrier, scavenges mitochondrial ROS, prevents mitochondrial DNA leakage, and blocks the cGAS‐STING pathway, thereby ...
Wenxuan Zheng, Zhicheng Wang, Xin Zhou, Shuya Wang, Xiaojing Shi, Tingli Xiong, Ruishi Li, Yuting Lin, Zhen Chen, Jiawen Wei, Fei Li, Jinwen Ge, Kelong Ai, Chong Liu, Guiming Deng   +14 more
wiley   +1 more source

The E3 Ligase RNF115 Aggravates Pathological Cardiac Hypertrophy via Ubiquitin‐Mediated Degradation of SPTBN1

Advanced Science, EarlyView.
In response to hypertrophic stimuli, increased c‑JUN phosphorylation upregulates RNF115, leading to SPTBN1 ubiquitination and degradation. which promotes F‑actin depolymerization and YAP activation, driving cardiac hypertrophy. The RNF115 inhibitor DTD effectively suppresses SPTBN1 ubiquitination and cardiac hypertrophy.
Yan Zu, Shiqing Chen, Ji Chen, Liuliu Ruan, Bowen Li, Weijian Chu, Shichen Huang, Dian Yu, Jing Tian, Yuhan Zhao, Yi Han, Xin Tang, Yong Ji   +12 more
wiley   +1 more source

Brain‐Computer Interface Training Fosters Perceptual Skills to Detect Errors

Advanced Science, EarlyView.
Accurate perception of visuomotor errors underpins motor precision and learning, yet conventional behavioral training fails to improve sensitivity to subtle errors. Real‐time EEG‐based brain‐computer interface feedback targeting the error positivity component enhances perceptual learning of small errors.
Deland H. Liu, Fumiaki Iwane, Minsu Zhang, Leonardo G. Cohen, José del R. Millán   +4 more
wiley   +1 more source

The Relationship of Neoadjuvant Taxanes, Anthracyclines, Cyclophosphamide Chemotherapy on Nutritional Status Based on Body Mass Index (BMI) and Albumin Measurements in Locally Advanced Stage Breast Cancer Patients in Bahteramas Hospital Kendari

Indonesian Journal of Cancer
Background: Breast cancer is a disease caused by cancer cells in breast tissue. The most frequently found is locally advanced. The locally advanced stage refers to stages IIIA, IIIB, and IIIC. Neoadjuvant is the treatment for locally advanced. The Taxane,
Afirah Khairunnisa S Limba, Ida Royani, Achmad Harun Muchsin, Irna Diyana Kartika Kamaluddin, Febie Irsandy   +4 more
doaj   +1 more source

Implementación de una estrategia webquest por medio de las tecnologías del aprendizaje y el conocimiento [tac] para el fortalecimiento de la lecto-escritura en la educación media

AiBi Revista de Investigación, Administración e Ingeniería, 2020
Las Tecnologías del Aprendizaje y Conocimiento [TAC] promueven cambios en los procesos de enseñanza y aprendizaje, ya que potencian las competencias digitales por medio del uso de las Tecnologías de la Información y Comunicación [TIC] y generan ...
Maria Isabel Osorio-Pita, Paulina Ermelinda Cabas-Gómez, Eleana Córdoba-Buenaños   +2 more
doaj   +1 more source