Results 61 to 70 of about 3,856 (257)

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Relevant factors for tacit knowledge transfer within organizations: an exploratory study Fatores relevantes à transferência de conhecimento tácito em organizações: um estudo exploratório

Gestão & Produção, 2012
Knowledge and management of such knowledge have been studied for some time now in the field of Management. However, in the 1990s, with the growth in the economy based on intangible assets, companies needed more than an unstructured approach to corporate ...
Bernardo Lemos, Luiz Antonio Joia
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source

A conceptual model of tacit knowledge transfer in steganography

International Journal of Engineering & Technology, 2018
Steganography is a technique that involves a secret hidden message concealed inside the media cover using formats such as text, images, video or audio. Secret messages sent from the sender to the receiver are considered as knowledge being transferred from the expert to the novice. However, previous studies related to the knowledge transfer from experts
Noor Hasnita Abdul Talib, Mazida Ahmad, Roshidi Din   +2 more
openaire   +2 more sources

Unique circulating miRNAome signatures captured with distinct molecular states in Lynch syndrome and sporadic colorectal cancer

Molecular Oncology, EarlyView.
Circulating microRNA profiles distinguish nonmalignant Lynch syndrome from cancer‐associated Lynch syndrome, sporadic colorectal cancer, and healthy controls. Age‐stratified analysis reveals disease‐specific regulatory states, and a six‐miRNA panel shows concordant separation in an independent colorectal tissue cohort.
Ramadhani Salum Chambuso, Md Shohel Ul Islam, Rosa M Xicola, Raj Ramesar, Xavier Llor, Sinclair Steele   +5 more
wiley   +1 more source

Geographies of tacit knowledge transfer: Evidence from the European co-authorship network

Moravian Geographical Reports, 2020
The patterns of scientific cooperation between the 28 European Union (EU) member countries, Switzerland and Norway, from 1993 and 2017, are evaluated in this article.
Jeck Tomáš, Baláž Vladimír
doaj   +1 more source

Targeting the EpCAM‐AXL axis to overcome drug resistance in lung cancer

Molecular Oncology, EarlyView.
Lung cancer cells often evade therapy by hijacking signaling pathways. We reveal that cleaved EpCAM (sEpCAM) stabilizes the oncogenic protein AXL, driving NF‐κB and STAT3‐mediated chemoresistance. This EpCAM‐AXL axis identifies a high‐risk patient subset with poor prognosis.
Alexa Guerrero‐Alba, Mark Shacker, Timothy P. Fleming, Michael A. Smith, Ross M. Bremner, Narendra V. Sankpal   +5 more
wiley   +1 more source

Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids

FEBS Open Bio, EarlyView.
Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão, Diogo M. Engrácia, Graça Soveral, Filipa Mendes   +3 more
wiley   +1 more source

Assessing the role of tacit knowledge in the management of state forest reserves of Namibia

Namibian Journal of Environment
Tacit knowledge is embedded in lived experience, cultural practice and social relations, and has long shaped forest use and stewardship in Namibia - yet it remains marginal in formal forest governance.
Michael S. David, Mechtilde Pinto, Tertu Iileka, Amon Andreas, Selma Lendelvo   +4 more
doaj   +1 more source

Teachers' tacit knowledge: A prolegomenic view [PDF]

Zbornik Radova Filozofskog Fakulteta u Prištini, 2013
We know the face of another person, and we can identify among thousands or even millions. Again, we are not able to speak and explain exactly how we recognize the person. We manage to bike, but it's hard to verbalize knowledge.
Živković Predrag Ž.
doaj