Results 91 to 100 of about 13,934 (307)

Energy‐Efficient and Sustainable Design Optimization for Ternary Mixture Separation: A Comparative Analysis of Sequential Iterative Optimization and Non‐Dominated Sorting Genetic Algorithm II

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study presents a comparative analysis of two optimization approaches: Sequential Iterative Optimization (SIO) and Non‐dominated Sorting Genetic Algorithm II (NSGA‐II) applied to the separation of ternary mixtures (1‐butanol, isobutanol, and 2‐butanol) using Dual‐Column Distillation (DCD) and Dividing‐Wall Column (DWC) processes. Through a
Ruijie Wang, Xinlan Weng, Xiaoxin Gao, Zhimeng Wang, Xiaoyu Kang, Zeyang Li   +5 more
wiley   +1 more source

Multi‐omic profiling reveals immune cell priming signature linked to lupus prognosis

Arthritis &Rheumatology, Accepted Article.
Objective Systemic lupus erythematosus (SLE) is a multi‐organ disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source

Mechanism‐informed machine learning for individualized tacrolimus dose adjustment in the early post‐kidney transplant period

British Journal of Clinical Pharmacology, EarlyView.
Abstract Aim Tacrolimus dosing in the early post‐kidney transplant period is challenging due to a narrow therapeutic index and substantial interindividual pharmacokinetic (PK) variability. This study aimed to develop and validate mechanism‐informed machine learning (ML) models to support individualized tacrolimus dosing during this critical period ...
Hui Yu, Zihan Qin, Logan S. Smith, Jeong M. Park, Hao‐Jie Zhu   +4 more
wiley   +1 more source

A novel molecular dynamics approach to simulate micromechanical behavior in characteristic crystallographic planes of transparent alumina ceramics

Journal of Materials Research and Technology
To investigate the anisotropic properties of brittle-prone transparent alumina ceramics (TACs) and guide the optimized design of material modification, this study employed a novel molecular dynamics (MD) approach to reproduce and analyze the anisotropic ...
Jiajun Chen, Meiqing Guo, Shaoying Zhang, Xinyue Wang, Xingming Zhu, Zhenhua Song, Zhiqiang Li   +6 more
doaj   +1 more source

Lack of Immediate Effects on Excitation and Interhemispheric Inhibition of the Human Motor Cortex [PDF]

, 2016
Transcranial alternating current stimulation (tACS) is a form of noninvasive brain stimulation and is capable of influencing brain oscillations and cortical networks.
Gundlach, Christopher, Hoff, Maike, Kaminski, Elisabeth, Ragert, Patrick, Rjosk, Viola, Sehm, Bernhard, Villringer, Arno   +6 more
core   +1 more source

New opportunities for bioscaffold‐enabled spinal cord injury repair

BMEMat, EarlyView.
Schematic illustration of bioscaffolds for spinal cord injury repair. We summarize the effects of bioscaffold properties on SCI repair, highlight different types of bioscaffolds, various fabrication strategies, and in vivo transformations for the clinical development of SCI‐repairing bioscaffolds.
Xiaoqing Qi, Yicheng Fu, Zhaoliang Su, Li Li, Subrata Chakrabarti, Peng Li, Yilun Wu, Fang Liu, Teng Gao, Zhifeng Dong, Lei Liu, Pei Cao   +11 more
wiley   +1 more source

Exploring the classical and numerical Delboeuf illusion: the impact of transcranial alternating current stimulation on magnitude processing [PDF]

PeerJ
Understanding cognitive and neural mechanisms underlying quantity processing is crucial for unraveling human cognition. The existence of a single magnitude system, encompassing non-symbolic number estimation alongside other magnitudes like time and space,
Maria Santacà, Francesco Carabba, Achini Mihindukulasooriya Fernando, Enrico Pitocco, Luca Battaglini, Umberto Granziol   +5 more
doaj   +2 more sources

Independent causal contributions of alpha- and beta-band oscillations during movement selection [PDF]

, 2016
To select a movement, specific neuronal populations controlling particular features of that movement need to be activated, whereas other populations are downregulated.
Brinkman, Loek, de Lange, Floris P., Dijkerman, H. Chris, Esterer, Sophie, Marshall, Tom R., Sharp, Poppy, Stolk, Arjen, Toni, Ivan   +7 more
core   +3 more sources

Improving Antioxidants and Physicochemical Properties of Wild Rice Noodles by Fortification With Carrot Powder

Cereal Chemistry, EarlyView.
ABSTRACT Background and Objectives Wild rice (WR), a nutritious cereal rich in phytochemicals, remains underutilized despite its health benefits. This study explored deep purple (DP), purple sun hybrid (PSH), purple haze (PH), cosmic purple (CP), and vistaric sky blue (VSB) carrot powders as fortificants in WR noodles at 10%, 20%, and 30% levels in ...
Beverly Cheruto Too, Daniel Zogona, Daniela Herrera Balandrano, Trust Beta   +3 more
wiley   +1 more source

Integration bile acid metabolomics and gut microbiome to study the anti-liver fibrosis effects of total alkaloids of Corydalis saxicola Bunting

Chinese Medicine
Background Bile acids and gut microbiota participate in the pathogenesis of liver fibrosis (LF). The total alkaloids of Corydalis saxicola Bunting (TACS) is a traditional Chinese medicine extract that has been used to treat LF, but the underlying ...
Qianyi Wang, MeiLing Zhang, Mingwei Meng, Zhuo Luo, Ziping Pan, Lijun Deng, Jinghua Qin, Bingjian Guo, Dan Zhu, Yanmin Zhang, Hongwei Guo, Yonghong Liang, Zhiheng Su   +12 more
doaj   +1 more source