Results 101 to 110 of about 14,076 (304)

Pharmacological treatment with inhibitors of nuclear export enhances the antitumor activity of docetaxel in human prostate cancer [PDF]

, 2017
Background and aims: Docetaxel (DTX) modestly increases patient survival of metastatic castration-resistant prostate cancer (mCRPC) due to insurgence of pharmacological resistance. Deregulation of Chromosome Region Maintenance (CRM-1)/ exportin-1 (XPO-1)-
Argueta, Christian, BIORDI, ASSUNTA LEDA, Biordi, Leda Assunta, Colapietro, Alessandro, Festuccia, Claudio, Flati, Vincenzo, Gravina, Giovanni Luca, Iorio, Roberto, Kauffman, Michael, Landesman, Yosef, Mancini, Andrea, Marampon, Francesco, Pompili, Simona, Sferra, Roberta, Shacham, Sharon   +14 more
core   +2 more sources

Design and Optimization of a Double‐Column Vapor Recompression Heat Pump Distillation Process via NSGA‐II for Separating Ternary Wide‐Boiling Mixtures

Asia-Pacific Journal of Chemical Engineering, EarlyView.
ABSTRACT This study proposes a novel double‐column vapor recompression heat pump (DCVRHP) distillation process for separating ternary wide‐boiling‐range mixtures under two different vapor conditions: n‐hexane/n‐heptane/n‐octane using low pressure steam and n‐hexanol/n‐octanol/n‐decanol using high pressure steam.
Zeyang Li, Xiaoxin Gao, Xiaoyu Kang, Ruijie Wang, Xiyuan Chen   +4 more
wiley   +1 more source

Phase-lagged tACS between executive and default mode networks modulates working memory

Scientific Reports
Transcranial alternating current stimulation (tACS) is an efficient neuromodulation technique to enhance cognitive function in a non-invasive manner.
Jeehye Seo, Dongha Lee, Dimitrios Pantazis, Byoung-Kyong Min   +3 more
doaj   +1 more source

Intervening Effects of Total Alkaloids of Corydalis saxicola Bunting on Rats With Antibiotic-Induced Gut Microbiota Dysbiosis Based on 16S rRNA Gene Sequencing and Untargeted Metabolomics Analyses

Frontiers in Microbiology, 2019
Gut microbiota dysbiosis induced by antibiotics is strongly connected with health concerns. Studying the mechanisms underlying antibiotic-induced gut microbiota dysbiosis could help to identify effective drugs and prevent many serious diseases.
Xi Liu, Hua Zheng, Rigang Lu, Huimin Huang, Hongjia Zhu, Chunli Yin, Yiyi Mo, Jinxia Wu, Xuwen Liu, Ming Deng, Danfeng Li, Bang Cheng, Fang Wu, Fang Wu, Yonghong Liang, Hongwei Guo, Hui Song, Zhiheng Su   +17 more
doaj   +1 more source

Modulation of speech-in-noise comprehension through transcranial current stimulation with the phase-shifted speech envelope [PDF]

, 2019
This work is licensed under a Creative Commons Attribution 4.0 License. For more information, see http://creativecommons.org/licenses/by/4.0/Neural activity tracks the envelope of a speech signal at latencies from 50 ms to 300 ms.
Kadir, Shabnam, Kaza, Chrysoula, Reichenbach, Tobias, Weissbart, Hugo   +3 more
core   +3 more sources

Material‐Driven Neuronal Oscillators and Filters via Active Reactance in CC‐NDR and VC‐NDR Electro‐Thermal Memristors

Advanced Physics Research, EarlyView.
Active reactance in electro‐thermal memristors emerges intrinsically from rapid thermal switching of device resistance, linking current‐controlled and voltage‐controlled negative differential resistance to neuronal spiking dynamics. Opposing temperature coefficients of resistance give rise to active inductive or capacitive responses, enabling tunable ...
Fatme Jardali, Gwyneth Svatek, R. Stanley Williams, Timothy D. Brown, Patrick J. Shamberger   +4 more
wiley   +1 more source

One Last Chance: The Economic Case for a New Approach to Fisheries Management in New England [PDF]

, 2009
Documents the decline of the New England fishing industry as a result of mismanagement, presents examples of successful and sustainable fisheries, and examines the viability of proposed community-based, fishermen-run cooperatives as a ...
Jon G. Sutinen, Robert J. Johnston
core  

The petrotympanic canal (Huguier canal): Evolutionary, anatomical, and medical perspectives

The Anatomical Record, EarlyView.
Abstract The petrotympanic canal, traditionally referred to as Civinini's or Huguier's canal, represents an anatomical passage connecting the middle ear and temporomandibular joint (TMJ). Despite its early description, its structural complexity and functional significance have often been underestimated. In this study, we combined historical, anatomical,
Andrea Papini, Nicola Montemurro, Ferdinando Paternostro, Immacolata Belviso, Massimo Galli, Petra Martini, Licia Uccelli, Jacopo Moggi‐Cecchi, Gregorio Oxilia   +8 more
wiley   +1 more source

Challenges of P300 Modulation Using Transcranial Alternating Current Stimulation (tACS)

Frontiers in Psychology, 2019
The P300 component of the event-related potential (ERP) is a well investigated phenomenon in the human electroencephalogram (EEG) and has been related to stimulus processing and attentional mechanisms.
Fabian Popp, Isa Dallmer-Zerbe, Alexandra Philipsen, Christoph S. Herrmann, Christoph S. Herrmann   +4 more
doaj   +1 more source

Multi‐Omic Profiling Reveals Immune Cell Priming Signature Linked to Lupus Prognosis

Arthritis &Rheumatology, EarlyView.
Objective Systemic lupus erythematosus (SLE) is a multiorgan disease with widespread immune dysregulation and significant unmet clinical need. Blood‐based gene expression studies have advanced our understanding of SLE pathogenesis but may overlook critical tissue‐specific mechanisms that drive disease heterogeneity and progression.
Michael A. Smith, Dominic Sinibaldi, Saifur Rahman, Chia‐Chien Chiang, Anna M. Hansen, Jill Henault, Carlos P. Roca, Shu Wang, Kamelia Zerrouki, Rebecca Filippi, Christopher Groves, Zerai Manna, Jun Chu, Michael Davis, Sarthak Gupta, Christopher Morehouse, Melissa de los Reyes, Rachel Ettinger, Roland Kolbeck, Mariana J. Kaplan, Miguel A. Sanjuan, Richard M. Siegel, Sarfaraz A. Hasni, Kerry A. Casey   +23 more
wiley   +1 more source