Results 121 to 130 of about 14,076 (304)

Coil-Tac: Coiled Capacitor Mechanism With Liquid Metal for Tactile Sensing

IEEE Robotics and Automation Letters
Exploiting the high conductivity and fluidity of liquid metal, Coil-Tac is a soft transduction mechanism based on measuring change in capacitance as a flowable liquid metal core moves within a conductive helical coil. Using finite difference methods, a model is derived that estimates the response of Coil-Tac with various coil pitches to within 0.0502 ...
George P. Jenkinson, Andrew T. Conn, Antonia Tzemanaki   +2 more
openaire   +1 more source

Clinical Model‐Informed Precision Dosing Consult Service for Accelerating Personalized Medication in Pediatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Traditional dosing strategies often rely on a “one‐size‐fits‐all” paradigm, assuming an “average” patient with typical demographic and pharmacological characteristics. In reality, this often overlooks existing between‐patient variability and can lead to suboptimal drug exposure or toxicity. This issue is especially pronounced in pediatric patients, who
Zachary L. Taylor, Takanobu Nadai, Kei Irie, Wen Rui Tan, Sanjana Parikh, Anhar Hosawi, Matthijs W. van Hoogdalem, Ronaldo Morales Junior, Sonya Tang Girdwood, Abbie D. Leino, Kana Mizuno, Alexander A. Vinks, Tomoyuki Mizuno   +12 more
wiley   +1 more source

An Experimental Analysis of a Points-Based System for Managing Multispecies Fisheries [PDF]

An industry group has proposed a novel system for managing the Northeast Multispecies Fishery. Each harvester would be endowed with a budget of points, and each species would have a “point price,†or number of points that must be paid out of his ...
Anderson, Christopher M.
core   +1 more source

Heterozygous Med13l mice recapitulate a developmental growth delay and craniofacial anomalies seen in MED13L syndrome

Developmental Dynamics, EarlyView.
Abstract Background Gene transcription is crucial for embryo and postnatal development and is regulated by the Mediator complex. Mediator is comprised of four submodules, including the kinase submodule (CKM). The CKM consists of MED13, MED12, CDK8, and CCNC.
Anna K. Leinheiser, Timothy T. Nguyen, Kayla M. Henry, Mariela Rosales, Eric Van Otterloo, Chad E. Grueter   +5 more
wiley   +1 more source

Role of SoxE transcription factors in development and disease

Developmental Dynamics, EarlyView.
Abstract Sox8, Sox9, and Sox10 arose by multiple rounds of genome duplications from a single SoxE gene in ancestral vertebrates. In this review, we will briefly discuss the molecular structure and function of SoxE transcription factors and their evolutionary origin. We will then discuss their expression, function, and developmental disorders.
Merin Lawrence, Gerhard Schlosser
wiley   +1 more source

Gut microbiota‐related modulation of immune mechanisms in post‐infarction remodelling and heart failure

ESC Heart Failure, Volume 12, Issue 2, Page 942-954, April 2025.
Abstract The immune system has long been recognized as a key driver in the progression of heart failure (HF). However, clinical trials targeting immune effectors have consistently failed to improve patient outcome across different HF aetiologies. The activation of the immune system in HF is complex, involving a broad network of pro‐inflammatory and ...
Johann Roessler, Friederike Zimmermann, Bettina Heidecker, Ulf Landmesser, Arash Haghikia   +4 more
wiley   +1 more source

CardiLect: A combined cross‐species lectin histochemistry protocol for the automated analysis of cardiac remodelling

ESC Heart Failure, Volume 12, Issue 2, Page 1398-1415, April 2025.
Abstract Background Cardiac remodelling, a crucial aspect of heart failure, is commonly investigated in preclinical models by quantifying cardiomyocyte cross‐sectional area (CSA) and microvascular density (MVD) via histological methods, such as immunohistochemistry.
Tamás G. Gergely, Tamás Kovács, Andrea Kovács, Viktória E. Tóth, Nabil V. Sayour, Gábor M. Mórotz, Csenger Kovácsházi, Gábor B. Brenner, Zsófia Onódi, Balázs Enyedi, Domokos Máthé, Przemyslaw Leszek, Zoltán Giricz, Péter Ferdinandy, Zoltán V. Varga   +14 more
wiley   +1 more source

Transcranial alternating current stimulation for neuropsychiatric disorders: a systematic review of treatment parameters and outcomes

Frontiers in Psychiatry
BackgroundTranscranial alternating current stimulation (tACS) alters cortical excitability with low-intensity alternating current and thereby modulates aberrant brain oscillations.
Fatemeh Gholamali Nezhad, Josh Martin, Vanessa K. Tassone, Vanessa K. Tassone, Alyssa Swiderski, Ilya Demchenko, Ilya Demchenko, Ilya Demchenko, Somieya Khan, Hamzah E. Chaudhry, Annalisa Palmisano, Annalisa Palmisano, Emiliano Santarnecchi, Venkat Bhat, Venkat Bhat, Venkat Bhat, Venkat Bhat, Venkat Bhat   +17 more
doaj   +1 more source

Application, Challenges, and Prospects of Non‐Thermal Processing Technologies for Seaweed Protein Extraction—A Review

Food Chemistry International, EarlyView.
This review highlights non‐thermal extraction technologies for seaweed proteins, emphasizing their mechanisms, impacts on protein structure and functionality, and sustainability potential. Key limitations related to species dependence, extract complexity, and scale‐up are discussed to guide future industrial and biorefinery applications.
Rahat Mahmud, Md Fuad Al Hasan, Shuvojit Roy, Tanvir Ahmed   +3 more
wiley   +1 more source

Modulating food craving-related neural oscillations using tACS: study protocol for a randomized sham-controlled trial

Frontiers in Human Neuroscience
IntroductionFood addiction is characterized by heightened craving and impaired inhibitory control, contributing to compulsive eating and obesity. Existing behavioral and pharmacological interventions often fail to achieve lasting effects.
Milos Ljubisavljevic, Milos Ljubisavljevic, Fransina C. King, Fransina C. King, Fatima Yousif Ismail, Yauhen Statsenko, Yauhen Statsenko, Shahid Bashir, Osama Abdullah, Osama Abdullah, Bas Rokers, Bas Rokers   +11 more
doaj   +1 more source