Results 161 to 170 of about 13,934 (307)

Gamma tACS over the prefrontal and parietal cortices enhances episodic memory performance. [PDF]

Front Hum Neurosci
Honma K, Nomura T.
europepmc   +1 more source

OSA Initiates Histone Lactylation That Drives PDE4B/FUS/AGT Axis to Pulmonary Hypertension

Cell Proliferation, EarlyView.
This study illustrates how chronic intermittent hypoxia (CIH) in obstructive sleep apnea (OSA) leads to hypertension via increased oxidative stress and mitochondrial dysfunction in pulmonary artery smooth muscle cells (PASMCs), causing glycolytic dysregulation. Lactate accumulation enhances histone lactylation, upregulating phosphodiesterase 4B (PDE4B),
Li Yang, Qing Ni, Yan He, Shijie Liu, Lulu Gan, Anni Dai, Yang Hu, Qian Liu, Xueling Yang, Jiqian Li, Yi Tao, Yunyu Li, Mingyue Xu   +12 more
wiley   +1 more source

Transcranial alternating current stimulation at 10 Hz promotes oligodendrogenesis and reduces g-ratio after cuprizone-induced demyelination. [PDF]

iScience
Scheinok TJ, Grognard M, D'Haeseleer M, Nagels G, De Bundel D, Van Schependom J.   +5 more
europepmc   +1 more source

AMSC‐sEVs Ameliorated Crohn's Disease by Inhibiting Macrophage‐Myofibroblast Transition Through the Delivery of MFGE8

Cell Proliferation, EarlyView.
Our study demonstrated that TGF‐β1 activated MAPK signalling pathway and promoted the MMT and secretion of CCL17 under CD‐associated intestinal inflammatory conditions. AMSC‐sEVs can deliver MFGE8, which inhibits MMT and CCL17‐mediated Treg recruitment by suppressing the MAPK signalling pathway, thereby alleviating intestinal fibrosis.
Minghao Xie, Qiang Liu, Zhizhong Xiong, Jian Li, Ruiri Jin, Lei Lian, Zhengrong Li   +6 more
wiley   +1 more source

Effects of 40 Hz transcranial alternating current stimulation on neural synchronization and cognitive correlates in schizophrenia: An EEG study. [PDF]

Transl Psychiatry
Liu Y, Cao X, Jin H, Li W, Yang F, Zhang T, Tang Y, Wang J, Davis JM, Hu S, Smith RC, Li C.   +11 more
europepmc   +1 more source

Further insights into the efficacy and moderators of transcranial alternating current stimulation for working memory. [PDF]

World J Psychiatry
Byeon H.
europepmc   +1 more source

The malate–aspartate shuttle supports thermogenic lipid mobilization in brown adipocytes

The FEBS Journal, EarlyView.
Brown fat cells burn lipids within their mitochondria to generate heat. This process involves two energy “shuttles,” one of which is naturally blocked during heat production. We found that the second shuttle (MASh) is not required to generate heat. However, when MASh is disabled, the fatty acids meant for fuel are instead converted back into stored fat.
Michaela Veliova, Caroline M. Ferreira, Katrina P. Montales, Francisco Villalobos, Alexandra J. Brownstein, Rebeca Acín‐Pérez, Gabrielly S. Ferreira, Anthony E. Jones, Linsey Stiles, Ajit S. Divakaruni, Marc Liesa, Orian S. Shirihai, Marcus F. Oliveira   +12 more
wiley   +1 more source

Transcranial Alternating Current Stimulation as an Adjuvant for Nonfluent Aphasia: A Proof-of-Concept Study. [PDF]

Bioengineering (Basel)
Keator LM, Johnson L, Newman-Norlund R, Spell K, Nemati S, Spell LA, den Ouden DB, Rorden C, Fridriksson J.   +8 more
europepmc   +1 more source

PET study of sphingosine-1-phosphate receptor 1 expression in response to vascular inflammation in a rat model of carotid injury [PDF]

, 2017
Abendschein, Dana R, Baum, Pamela, Han, Junbin, Jin, Hongjun, Liu, Hui, Tu, Zhude, Yue, Xuyi   +6 more
core   +2 more sources

Visual Modelling to Predict Behavioural Responses of Catsharks, Skates, and Plaice to Artificial Light for Use in Bycatch Reduction

Fisheries Management and Ecology, EarlyView.
ABSTRACT Light can be used to deter bycatch from fishing nets, but few studies have aimed to quantify how species view and respond to light. Here, we used visual models to predict how target (plaice Pleuronectes platessa) and bycatch (small‐spotted catshark Scyliorhinus canicular and undersized skates, Raja spp) species, captured in mixed demersal ...
Jasmine Somerville, Jon Blount, Martin Stevens   +2 more
wiley   +1 more source