Results 201 to 210 of about 14,076 (304)

Prediabetic cardiomyopathy is attenuated by hypothalamic PVN oxytocin neuron activation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend A long‐term high‐fat, high‐fructose diet induces prediabetes with insulin resistance, hyperinsulinaemia, elevated triglycerides and metabolic‐associated steatotic liver disease (MASLD) in male rats. Animals developed prediabetic cardiomyopathy characterized by diastolic dysfunction, interstitial fibrosis and tachycardia ...
Anna Nilsson   +7 more
wiley   +1 more source

Causal Evidence for Prefrontal-Motor Coupling in Reward-Responsive Goal-Directed Behavior. [PDF]

open access: yesJ Neurosci
Riddle J   +5 more
europepmc   +1 more source

Ro5‐4864, a ligand of the mitochondrial translocator protein, protects against heart failure in mice via regulation of the p62‐Keap1‐Nrf2 axis

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Graphical abstract of the proposed Ro5‐4864 mechanism of action via p62‐Keap1‐Nrf2 axis in heart failure. TSPO, the 18‐kDa mitochondrial translocator protein of the outer mitochondrial membrane, can directly interact with p62 (also known as SQSTM1), which is crucial for the degradation of damaged mitochondria by autophagy ...
Daphne A. Diloretto   +7 more
wiley   +1 more source

4D ultrasound reveals regional left atrial strain remodelling in a murine model of reversible pressure overload

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Traditional planar imaging approaches of the left atrium do not capture complex geometry. Four‐dimensional imaging allows the acquisition of 3D data + time to visualize left atrial geometry and kinematics. We designed an advanced analysis technique to investigate left atrial biomechanics in a model of pressure overload and ...
John P. Salvas   +3 more
wiley   +1 more source

Combined effects of prohexadione‐calcium and growing environment on sweet cherry fruit quality and postharvest performance

open access: yesJournal of the Science of Food and Agriculture, Volume 106, Issue 8, Page 4901-4912, June 2026.
Abstract BACKGROUND Sweet cherry (Prunus avium L.) is a high‐value fruit crop, but its commercial success is often limited by poor pigmentation, reduced firmness, and short shelf life. This study evaluated the effects of preharvest applications of prohexadione‐calcium (1.5 L ha−1) on fruit quality and storage performance in lowland and hilly orchards ...
Alice Varaldo   +3 more
wiley   +1 more source

Progress in non-invasive neuromodulation based on consciousness-related neural circuits: a narrative review. [PDF]

open access: yesFront Neurol
Wang Y   +14 more
europepmc   +1 more source

Detrimental Effect of Low‐Magnitude High‐Frequency Vibration in an Ex Vivo Model of Intervertebral Disc Degeneration Despite Estrogen Treatment

open access: yesJOR SPINE, Volume 9, Issue 2, June 2026.
Low‐magnitude high‐frequency vibration (LMHFV), with or without 17β‐oestradiol (E2), exacerbated papain‐induced bovine intervertebral disc degeneration, reducing cell viability, impairing matrix production, and increasing inflammation. E2 showed no protective effect against papain‐induced degeneration or LMHFV.
Jan Ulrich Jansen   +9 more
wiley   +1 more source

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