Results 61 to 70 of about 6,101 (214)

Phase-lagged tACS between executive and default mode networks modulates working memory

Scientific Reports
Transcranial alternating current stimulation (tACS) is an efficient neuromodulation technique to enhance cognitive function in a non-invasive manner.
Jeehye Seo, Dongha Lee, Dimitrios Pantazis, Byoung-Kyong Min   +3 more
doaj   +1 more source

Ilexoside K Ameliorates Atherosclerosis by Suppressing CD72hi Macrophages and Blocking CXCL12–CXCR4 Axis to Inhibit Endothelial Pyroptosis

Advanced Science, EarlyView.
CD72hi macrophages drive endothelial pyroptosis and accelerate atherosclerosis through CXCL12–CXCR4‐mediated immune–vascular crosstalk. Ilexoside K suppresses this pathogenic communication by modulating CXCR4‐dependent endothelial responses, reducing inflammation and plaque progression. These findings reveal a macrophage–endothelial regulatory axis and
Xingling He, Sijing Li, Jiahui Chen, Liyu Lin, Xinyu Li, Xiaojiao Zhang, Yihui Zhang, Xingling Chen, Jinjian Guo, Zhongqi Yang, Lu Lu, Shihao Ni   +11 more
wiley   +1 more source

Effectiveness and brain mechanism of multi-target transcranial alternating current stimulation (tACS) on motor learning in stroke patients: study protocol for a randomized controlled trial

Trials
Background Transcranial alternating current stimulation (tACS) has proven to be an effective treatment for improving cognition, a crucial factor in motor learning.
Ming-Hui Lai, Xiao-Ming Yu, Yan Lu, Hong-Lin Wang, Wang Fu, Huan-Xia Zhou, Yuan-Li Li, Jun Hu, Jiayi Xia, Zekai Hu, Chun-Lei Shan, Feng Wang, Cong Wang   +12 more
doaj   +1 more source

Single‐Nucleus Transcriptomic Atlas of Human Vellus Hair Pilosebaceous Units Reveals Age‐Associated Remodeling

Advanced Science, EarlyView.
Human vellus pilosebaceous units (PSUs) remain uncharted. This single‐nucleus atlas reveals coordinated remodeling of the aging PSU niche: reduced bulge stem cell representation with altered regenerative programs, increased representation of a stress‐responsive channel+ epithelial state, enhanced androgen‐responsive sebaceous programs, reduced ...
Ya'nan Li, Zhuoqiong Qiu, Xiaoyu Pan, Geyang Xu, Shanshan Peng, Ronghui Zhu, Qiuyang Luo, Xiaokai Fang, Xu Yao, Wei Li   +9 more
wiley   +1 more source

Mitochondrial Localization of Cx26 Promotes Colorectal Cancer Malignancy and Exposes a Fatal Vulnerability to Drug Targeting

Advanced Science, EarlyView.
Mitochondrial localization of Cx26 emerges as a double‐edged sword in colorectal cancer. PIMT‐mediated methylation of Cx26 promotes its mitochondrial localization and stability. Mitochondrial Cx26 then facilitates ER‐mitochondria communication and Ca2+ signaling, thereby promoting metastatic progression. Bortezomib exploits this malignant adaptation by
Jie Wang, Lu Chen, Jia Qin, Xiaoning Wang, Sunlan Ye, Ning An, Mei Bai, Yan Shen, Xuefeng Wu, Qiang Xu   +9 more
wiley   +1 more source

Drift Reduction in 2D PtSe2 Piezoresistive Pressure Sensors Through an On‐Chip Wheatstone Bridge

Advanced Electronic Materials, EarlyView.
Drift is a major source of error affecting the accuracy and repeatability of sensors. A Wheatstone bridge (WSB) enables high sensitivity, accuracy, and the elimination of common‐mode drift. We apply the WSB concept to highly sensitive piezoresistive pressure sensors made with two‐dimensional layered platinum diselenide transducers.
Ragini Gupta, Sebastian Lukas, Nico Rademacher, Michael Gross, Nikolas Dominik, Georg S. Duesberg, Max C. Lemme   +6 more
wiley   +1 more source

Intervening Effects of Total Alkaloids of Corydalis saxicola Bunting on Rats With Antibiotic-Induced Gut Microbiota Dysbiosis Based on 16S rRNA Gene Sequencing and Untargeted Metabolomics Analyses

Frontiers in Microbiology, 2019
Gut microbiota dysbiosis induced by antibiotics is strongly connected with health concerns. Studying the mechanisms underlying antibiotic-induced gut microbiota dysbiosis could help to identify effective drugs and prevent many serious diseases.
Xi Liu, Hua Zheng, Rigang Lu, Huimin Huang, Hongjia Zhu, Chunli Yin, Yiyi Mo, Jinxia Wu, Xuwen Liu, Ming Deng, Danfeng Li, Bang Cheng, Fang Wu, Fang Wu, Yonghong Liang, Hongwei Guo, Hui Song, Zhiheng Su   +17 more
doaj   +1 more source

Performance and Environmental Impact of Flexible Temperature Sensors on Cellulose‐Based Substrate

Advanced Electronic Materials, EarlyView.
Toward low‐environmental‐impact approach to thin‐film sensors fabrication using natural ingredient‐based triacetyl cellulose (TAC) substrate. Temperature sensors are fabricated and characterized based on thermal and mechanical performance. Substrate recovery is demonstrated by facile dissolution of a Mo‐based sensor in deionized water.
Dianne C. Corsino, Diego Ferri, Claudio Bonizzoni, Marco Affronte, Shuvaraj Ghosh, Stefania Benedetti, Alberto Rota, Antonio Ballestrazzi, Luca Pasquali, Ahmed Rasheed, Luisa Petti, Hafiza Faiqa Maqsood, Niko Münzenrieder, Roberto Rosa, Giuseppe Cantarella   +14 more
wiley   +1 more source

Integration bile acid metabolomics and gut microbiome to study the anti-liver fibrosis effects of total alkaloids of Corydalis saxicola Bunting

Chinese Medicine
Background Bile acids and gut microbiota participate in the pathogenesis of liver fibrosis (LF). The total alkaloids of Corydalis saxicola Bunting (TACS) is a traditional Chinese medicine extract that has been used to treat LF, but the underlying ...
Qianyi Wang, MeiLing Zhang, Mingwei Meng, Zhuo Luo, Ziping Pan, Lijun Deng, Jinghua Qin, Bingjian Guo, Dan Zhu, Yanmin Zhang, Hongwei Guo, Yonghong Liang, Zhiheng Su   +12 more
doaj   +1 more source

Majority‐Voting Overlapping Method for Error Correction in DNA Data Storage

Advanced Intelligent Discovery, EarlyView.
We propose an overlapping‐based majority‐voting method for DNA data storage error correction. By aligning multiple reads and choosing the most frequent base per position, it suppresses substitution errors without prior models. Validated on synthetic and real sequencing data, it achieves high‐fidelity, scalable, and cost‐effective reconstruction ...
Thi Bich Ngoc Nguyen, Seongjun Seo, Anshula Tandon, Nguyen Kim Uyen, Thi Hong Nhung Vu, Sung Ha Park   +5 more
wiley   +1 more source