Results 201 to 210 of about 48,744 (288)

Dose-dependent sensitivity of human three-dimensional chromatin to a heart disease-linked transcription factor. [PDF]

Science
Grant ZL, Kuang S, Zhang S, Horrillo AJ, Chen Z, Rao KS, Celen C, Kameswaran V, Joubran C, Lau PK, Dong K, Yang B, Bartosik WM, Zemke NR, Ren B, Srivastava D, Kathiriya IS, Pollard KS, Bruneau BG.   +18 more
europepmc   +1 more source

A quantitative dissection of the DNA‐binding properties of pathogenic GATA1 mutants

The FEBS Journal, Volume 293, Issue 17, Page 5140-5144, September 2026.
Transcription factor activity is influenced by cell context, accessibility of target sequences, and co‐factor recruitment. Quantitatively characterizing the consequences of individual mutations in the transcription factors or their target sequences remains technically challenging. Zambo et al. use mutant GATA1‐ATP2B4 binding to illustrate an innovation
Kaoru Takasaki
wiley   +1 more source

Success Rate of Immediately Loaded Orthodontic Temporary Anchorage Devices: A Retrospective Analysis of Patient- and Treatment-Related Factors. [PDF]

Bioengineering (Basel)
Martha K, Pop SI, Farczadi L, Pop RV, Dudás C, Jánosi KM.   +5 more
europepmc   +1 more source

Dolutegravir population pharmacokinetics in racially, sex‐ and age‐diverse and antiretroviral therapy‐experienced adults with HIV in the United States

HIV Medicine, Volume 27, Issue 9, Page 1517-1529, September 2026.
Abstract Objectives Dolutegravir (DTG) has been associated with weight gain in women with HIV, Black people with HIV and people with HIV60 years. This study aimed to characterise DTG population pharmacokinetics (PopPK) in a diverse population including these sub‐populations.
Adrian Khoei, Andrew Edmonds, Yen Chang, Catalina Ramirez, Mackenzie Vogan, Amanda Poliseno, Steven Wolinsky, Ken Ho, Todd T. Brown, Joseph B. Margolick, Jacquett Batson, Jennifer Hoffmann, Mark A. Marzinke, Mirjam‐Colette Kempf, Maria L. Alcaide, Joffi Effoe, Cecile D. Lahiri, Igho Ofotokun, Anandi N. Sheth, Stephen Gange, Audrey L. French, Bani Tamraz, Bradley E. Aouizerat, Phyllis C. Tien, Seble G. Kassaye, Jack DeHovitz, Kathryn Anastos, Kara W. Chew, Michelle Floris‐Moore, Julie B. Dumond   +29 more
wiley   +1 more source

Correlation between perioperative surgical factors and implant-related complications in the basicervical fractures of femoral neck treated with proximal femoral nail antirotation: a retrospective review study in 149 elderly patients. [PDF]

Eur J Orthop Surg Traumatol
Sa-Ngasoongsong P, Angkavanich N, Sabsuantang K, Sirisreetreerux N, Pengrung N, Kulachote N.   +5 more
europepmc   +1 more source

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

New Phytologist, Volume 251, Issue 5, Page 2799-2817, September 2026.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi, Jordana Oliveira, Franco Magurno, Alessandra Salvioli di Fossalunga, Mara Novero, Luisa Lanfranco, Stefano Ghignone, Gökalp Yildirir, Yan Wang, Paola Bonfante, Nicolas Corradi   +10 more
wiley   +1 more source

Targeted axillary dissection versus sentinel lymph node biopsy after neoadjuvant chemotherapy: are we underestimating the clinical significance of staging accuracy? [PDF]

Transl Breast Cancer Res
Venkataraman J, Mokbel K.
europepmc   +1 more source

The Role of Fat‐Free Mass in Weight‐Related Complications: A Rapid Review and Meta‐Analysis

Obesity Reviews, Volume 27, Issue 9, September 2026.
ABSTRACT Background This review synthesized evidence on the association between fat‐free mass (FFM) metrics and weight‐related metabolic complications in adults with overweight or obesity. Methods A systematic search of Medline, Embase, Web of Science, and Google Scholar (inception to October 2024) identified 32 observational studies involving 138,935 ...
Tadesse Asmamaw Dejenie, Paul P. Fahey, Haider Mannan, Mohammad Ariya, Evan Atlantis   +4 more
wiley   +1 more source

Axillary surgical de-escalation after neoadjuvant therapy in breast cancer: current evidence, clinical controversies, and future directions. [PDF]

Front Oncol
Ma J, Zhao G, Sun J, Guo H, Ding Y, Fan Z, Wang X.   +6 more
europepmc   +1 more source